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Weekend Rn Jobs in Saint Charles, MO (NOW HIRING)

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

Mercy

RN Weekend - Operating Room

Saint Louis, MO · On-site

$16K/mo

Louis Hospital Main Operating Room RN Weekend- Experienced OR RNs Only! $7,500 Sign On Bonus for Experienced OR RNs Who We Are: The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma ...

NHC

RN Registered Nurse

Saint Charles, MO · On-site

$41 - $47/hr

Ask about our Every Weekend Option! What You'll Do * Collaborate with the care team on assessments and care planning * Deliver skilled nursing care and treatments * Supervise LPNs and other nursing ...

Luxor Healthcare

Weekend Wound Nurse

Saint Louis, MO · On-site

$35 - $37/hr

We are looking for a Weekend Wound Care Nurse LPN / RN (WCC, WOCN) to join our team, providing support across multiple buildings in a flexible float-style role to assist with weekend wound care needs.

Luxor Healthcare

Weekend Wound Nurse

Saint Louis, MO · On-site

$35 - $37/hr

We are looking for a Weekend Wound Care Nurse LPN / RN (WCC, WOCN) to join our team, providing support across multiple buildings in a flexible float-style role to assist with weekend wound care needs.

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in Saint Charles, MO

Weekend Rn information

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs

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The most popular types of Rn jobs in Saint Charles, MO are:

What are popular job titles related to Weekend Rn jobs in Saint Charles, MO?

For Weekend Rn jobs in Saint Charles, MO, the most frequently searched job titles are:

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The top searched job categories for Weekend Rn jobs in Saint Charles, MO are:

What cities near Saint Charles, MO are hiring for Weekend Rn jobs?

Cities near Saint Charles, MO with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in Saint Charles, MO as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 28% Part Time, 2% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.

RN Weekend - Operating Room

Mercy

Saint Louis, MO • On-site

$16K/mo

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 9 days ago

Mercy rating

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

612th of 898 rated healthcare providers

Job description

Find your calling at Mercy! Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care. Evaluates the overall effectiveness of care provided by other direct caregivers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details: Join Mercy St. Louis HospitalMain Operating Room RN Weekend- Experienced OR RNs Only!

$7,500 Sign On Bonus for Experienced OR RNs

Who We Are:

The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center and Burn Center, delivering high-quality surgical care to patients of all ages, including pediatrics.

27 Operating Rooms

Breakdown of Teams:

  • General Surgery: general, burn, plastics, bariatric, colorectal

  • Gyn Service Line: GYN, urology, and robotics

  • Specialty Service Line: ortho & neuro

  • ENT Service Line: ENT, OMF, dental, peds, and ophthalmology

  • Off shift

At Mercy, we believe careers should align not only with your skills, but also with your heart. We support individuality, purpose, and professional growth—and we’re proud to be recognized by Modern Healthcare Magazine as one of the “Top 100 Places to Work.”

Qualifications:

Required Education:

  • Nursing degree from an accredited school

License:

  • Current Registered Nurse (RN) license in the State of Missouri

Certifications:

  • BLS required

We Offer Great Benefits!

Eligible coworkers enjoy an extensive benefits package, starting day one, including:

Financial & Career Support

  • Stay Pay Program

  • ASN to BSN Bridge Program – up to $16,000

  • BSN to MSN Bridge Program – up to $16,000

  • Tuition Reimbursement – up to $2,000 annually

  • Annual merit increases based on performance

  • Competitive salary

  • Future career growth opportunities

  • Relocation assistance available

Health & Wellness

  • Day-one medical, dental, and vision insurance

  • Paid parental leave

  • Generous PTO

  • 401(k) with employer match

  • $100/month annual contribution to eligible coworkers enrolled in the Dependent Care FSA

Questions or Interested in Learning More?

Please contact:
Stephanie Royer, Nurse Recruiter
📧 stephanie.royer@mercy.net

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.

What Mercy employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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