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Weekend Rn Jobs in O Fallon, MO (NOW HIRING)

Mercy

RN Weekend - Main Operating Room

Saint Louis, MO · On-site

Mercy St Louis Hospital Registered Nurse (RN) Weekend Option Seeking OR experience! Sign On Bonus Available! Who We Are The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center ...

Aveanna Healthcare

Registered Nurse (RN)

Wentzville, MO · On-site

$32 - $37/hr

Caring In Action RN Responsibilities Include: * Execution of physician's prescribed plan of care ... Flexible shifts and scheduling (8, 12, or 16-hour shifts; days/nights/weekends available ...

Aveanna Healthcare

Registered Nurse (RN)

Florissant, MO · On-site

$36 - $38/hr

Caring In Action RN Responsibilities Include: * Execution of physician's prescribed plan of care ... Flexible shifts and scheduling (8, 12, or 16-hour shifts; days/nights/weekends available ...

Aveanna Healthcare

Registered Nurse (Rn)

Fenton, MO · On-site

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (Rn)

Wentzville, MO · On-site +1

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (Rn)

Florissant, MO · On-site +1

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts- we will work with your availability! * 24/7 Local support from ...

CNSCares

Registered Nurse (RN)

O Fallon, MO · On-site

$45 - $50/hr

Description Registered Nurse - RN Private Duty Caregiver Part-Time Hours Available Pay Rate: $45 ... Must have every other weekend availability (Saturday and Sunday) * Must be willing to travel up to ...

Benedictine

RN

Saint Louis, MO

$42 - $46/hr

Louis Campus Name Nazareth Living Center Category RN/LPN Position Type Full-Time Shift Days Specific Shift Times 645a-315p Scheduled Days of the Week varies Weekend Work Requirement Every Other ...

SSM Health

Registered Nurse

Saint Louis, MO · On-site

Every 3rd weekend **Sign-on bonuses are available to external, qualified candidates. Internal ... And * Registered Professional Nurse (RN) - Illinois Department of Financial and Professional ...

Benedictine

RN

Saint Louis, MO

$42 - $46/hr

Louis Campus Name Nazareth Living Center Category RN/LPN Position Type Full-Time Shift Days Specific Shift Times 645a-315p Scheduled Days of the Week varies Weekend Work Requirement Every Other ...

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Weekend Rn information

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$25

$40

$68

How much do weekend rn jobs pay per hour?

As of May 31, 2026, the average hourly pay for weekend rn in O'Fallon, MO is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.01 per hour, depending on experience, location, and employer.

What Does a Weekend RN Do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

How to make an extra $1000 a month as a nurse?

Weekend RNs can increase their income by taking on additional shifts, working overtime, or picking up per diem assignments. Gaining specialized certifications, such as in IV therapy or wound care, can also qualify you for higher-paying roles or agency work, helping you reach your income goal more quickly.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

More about Weekend Rn jobs
What are the most commonly searched types of Rn jobs in O'Fallon, MO? The most popular types of Rn jobs in O'Fallon, MO are:
What are popular job titles related to Weekend Rn jobs in O'Fallon, MO? For Weekend Rn jobs in O'Fallon, MO, the most frequently searched job titles are:
What job categories do people searching Weekend Rn jobs in O'Fallon, MO look for? The top searched job categories for Weekend Rn jobs in O'Fallon, MO are:
What cities near O'Fallon, MO are hiring for Weekend Rn jobs? Cities near O'Fallon, MO with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in O'Fallon, MO as of May 2026, with employment types broken down into 2% As Needed, 62% Full Time, 18% Part Time, 1% Temporary, 16% Contract, and 1% Nights. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $84,714 per year, or $40.7 per hour.
RN Weekend - Main Operating Room

RN Weekend - Main Operating Room

Mercy

Saint Louis, MO • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired 2 days ago. Applications are no longer accepted.

Mercy rating

6.6

Company rating: 6.6 out of 10

Based on 200 frontline employees who took The Breakroom Quiz

556th of 864 rated healthcare providers

Job description

Find your calling at Mercy!Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care. Evaluates the overall effectiveness of care provided by other direct caregivers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards.Position Details:Mercy St Louis Hospital

Registered Nurse (RN) Weekend Option

Seeking OR experience!

Sign On Bonus Available!

Who We Are

The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center and Burn Center, delivering high-quality surgical care to patients of all ages, including pediatrics.

  • 27 Operating Rooms

  • Seven specialty teams, including:

    • General Surgery

    • Gynecologic Surgery

    • Urologic Surgery

    • Robotic Surgery

    • Ear, Nose, and Throat (ENT)

    • Orthopedic Surgery

    • Neurosurgery

  • Four state-of-the-art surgical robots

At Mercy, we believe careers should align not only with your skills, but also with your heart. We support individuality, purpose, and professional growth—and we’re proud to be recognized by Modern Healthcare Magazine as one of the “Top 100 Places to Work.”

Education: Graduate of an accredited nursing program.
Licensure: Active RN licensure in the state of practice.
Experience: Must have Operating Room RN experience
Certifications: BLS through American Heart Association

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you‘ll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you‘ll grow with us.

What Mercy employees say

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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