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Weekend Rn Jobs in O Fallon, MO (NOW HIRING)

Mercy

RN Weekend - Main Operating Room

Saint Louis, MO · On-site

Mercy St Louis Hospital Registered Nurse (RN) Weekend Option Seeking OR experience! Sign On Bonus Available! Who We Are The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center ...

Aveanna Healthcare

Registered Nurse (RN)

Saint Louis, MO · On-site

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (RN)

Wentzville, MO

$32 - $37/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Mercy

RN Weekend - Main Operating Room

Saint Louis, MO · On-site

Mercy St Louis Hospital Registered Nurse (RN) Weekend Option Seeking OR experience! Sign On Bonus Available! Who We Are The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center ...

Aveanna Healthcare

Registered Nurse (RN)

Fenton, MO · On-site

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (RN)

Saint Louis, MO · On-site

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (RN)

Florissant, MO

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Luxor Healthcare

Weekend Wound Nurse

Saint Louis, MO · On-site

$35 - $37/hr

We are looking for a Weekend Wound Care Nurse LPN / RN (WCC, WOCN) to join our team, providing support across multiple buildings in a flexible float-style role to assist with weekend wound care needs.

Aveanna Healthcare

Registered Nurse (RN)

Fenton, MO · On-site

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (RN)

Florissant, MO · On-site

$36 - $38/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Aveanna Healthcare

Registered Nurse (RN)

Saint Peters, MO · On-site

$32 - $37/hr

Registered Nurse - RN We are one of the largest private duty nursing companies in the nation and ... Days, nights, and weekend shifts-- we will work with your availability! * 24/7 Local support from ...

Luxor Healthcare

Weekend Wound Nurse

Saint Louis, MO

$35 - $37/hr

We are looking for a Weekend Wound Care Nurse LPN / RN (WCC, WOCN) to join our team, providing support across multiple buildings in a flexible float-style role to assist with weekend wound care needs.

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All JobsWeekend Rn JobsWeekend Rn Jobs in O'Fallon, MO

Weekend Rn information

See O Fallon, MO salary details

$25

$40

$68

How much do weekend rn jobs pay per hour?

As of Jun 28, 2026, the average hourly pay for weekend rn in O'Fallon, MO is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.01 per hour, depending on experience, location, and employer.

What Does a Weekend RN Do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What jobs pay 2000 a day?

Jobs that can pay $2,000 a day typically include high-level roles such as specialized medical professionals like surgeons or anesthesiologists, certain executive positions, or freelance consultants with in-demand expertise. These roles often require advanced skills, certifications, or significant experience, and may involve working long hours or on a contract basis. For example, some travel nurses or locum tenens physicians can reach this earning level with overtime or high-demand specialties.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

Can you make $50 an hour as a nurse?

Weekend RNs can potentially earn $50 an hour or more, especially with specialized skills, certifications, and experience. Pay rates vary by location, facility, and shift, with weekend and night shifts often offering higher compensation. However, achieving this rate depends on factors such as demand, employer policies, and individual qualifications.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

How to make an extra $1000 a month as a nurse?

Weekend RNs can increase their income by taking on additional shifts, working overtime, or picking up per diem assignments. Gaining specialized certifications in areas like IV therapy or wound care can also command higher pay rates, helping to reach the extra $1000 per month goal.

How to make $150,000 as a nurse?

To earn $150,000 as a Weekend RN, gaining experience in high-demand specialties like ICU or anesthesia, obtaining certifications such as CCRN or CRNA, and working overtime or in travel nursing roles can increase income. Working in regions with higher pay rates and taking on additional shifts also contribute to reaching this salary level.
More about Weekend Rn jobs
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What cities near O'Fallon, MO are hiring for Weekend Rn jobs? Cities near O'Fallon, MO with the most Weekend Rn job openings:
Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in O'Fallon, MO as of June 2026, with employment types broken down into 1% As Needed, 52% Full Time, 21% Part Time, and 26% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $84,714 per year, or $40.7 per hour.
RN Weekend - Main Operating Room

RN Weekend - Main Operating Room

Mercy

Saint Louis, MO

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 7 days ago

Mercy rating

6.4

Company rating: 6.4 out of 10

Based on 204 frontline employees who took The Breakroom Quiz

523rd of 877 rated healthcare providers

Job description

Find your calling at Mercy! Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care. Evaluates the overall effectiveness of care provided by other direct caregivers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details: Mercy St Louis Hospital

Registered Nurse (RN) Weekend Option

Seeking OR experience!

Sign On Bonus Available!

Who We Are

The Main Operating Room at Mercy St. Louis Hospital is a Level I Trauma Center and Burn Center , delivering high-quality surgical care to patients of all ages, including pediatrics.

  • 27 Operating Rooms

  • Seven specialty teams , including:

    • General Surgery

    • Gynecologic Surgery

    • Urologic Surgery

    • Robotic Surgery

    • Ear, Nose, and Throat (ENT)

    • Orthopedic Surgery

    • Neurosurgery

  • Four state-of-the-art surgical robots

At Mercy, we believe careers should align not only with your skills, but also with your heart. We support individuality, purpose, and professional growth—and we’re proud to be recognized by Modern Healthcare Magazine as one of the “Top 100 Places to Work.”

Education: Graduate of an accredited nursing program.
Licensure: Active RN licensure in the state of practice.
Experience: Must have Operating Room RN experience
Certifications: BLS through American Heart Association
 

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.

What Mercy employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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