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Weekend Rn Jobs in O Fallon, MO (NOW HIRING)

Mercy

RN, Weekend, Nights, FT

Saint Louis, MO

$5.0K/wk

... (RN) - Med Surg 5W New Grads and Experienced Nurses Welcome! Location: Mercy Hospital South - 10010 Kennerly Rd, St. Louis, Missouri 63128 Schedule: Full-Time | 36 hours/week Shift: Weekend, Night ...

New

Mercy

RN, Weekend, Nights, FT

Saint Louis, MO · On-site

$5.0K/wk

... (RN) - Med Surg 5W New Grads and Experienced Nurses Welcome! Location: Mercy Hospital South - 10010 Kennerly Rd, St. Louis, Missouri 63128 Schedule: Full-Time | 36 hours/week Shift: Weekend, Night ...

New

Mercy

RN, Weekend, Nights, FT

Saint Louis, MO · On-site

$5.0K/wk

... (RN) - Med Surg 5W New Grads and Experienced Nurses Welcome! Location: Mercy Hospital South - 10010 Kennerly Rd, St. Louis, Missouri 63128 Schedule: Full-Time | 36 hours/week Shift: Weekend, Night ...

New

TNAA TotalMed RN

Travel RN First Assist

Saint Louis, MO · On-site

TNAA TotalMed RN is seeking a travel nurse RN First Assist for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: First Assist * Discipline: RN * Duration: 13 weeks * 40 hours ...

TNAA TotalMed RN

Travel Pediatric OR RN

Saint Louis, MO · On-site

TNAA TotalMed RN is seeking a travel nurse RN Pediatrics OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: Pediatrics OR - Operating Room * Discipline ...

TNAA TotalMed RN

Travel Pediatric OR RN

Saint Louis, MO · On-site

TNAA TotalMed RN is seeking a travel nurse RN Pediatrics OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: Pediatrics OR - Operating Room * Discipline ...

TNAA TotalMed RN

Travel Pediatric OR RN

Saint Louis, MO · On-site

TNAA TotalMed RN is seeking a travel nurse RN Pediatrics OR - Operating Room for a travel nursing job in Saint Louis, Missouri. & Requirements * Specialty: Pediatrics OR - Operating Room * Discipline ...

Mercy

RN, Weekend, Nights, FT

Saint Louis, MO · On-site

$5.0K/wk

... (RN) - Med Surg 5W New Grads and Experienced Nurses Welcome! Location: Mercy Hospital South - 10010 Kennerly Rd, St. Louis, Missouri 63128 Schedule: Full-Time | 36 hours/week Shift: Weekend, Night ...

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All JobsRn JobsWeekend Rn JobsWeekend Rn Jobs in O'Fallon, MO

Weekend Rn information

See O Fallon, MO salary details

$25

$40

$68

How much do weekend rn jobs pay per hour?

As of Aug 16, 2026, the average hourly pay for weekend rn in O'Fallon, MO is $40.73, according to ZipRecruiter salary data. Most workers in this role earn between $32.32 and $47.01 per hour, depending on experience, location, and employer.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.
More about Weekend Rn jobs

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The most popular types of Rn jobs in O'Fallon, MO are:

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For Weekend Rn jobs in O'Fallon, MO, the most frequently searched job titles are:

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What cities near O'Fallon, MO are hiring for Weekend Rn jobs?

Cities near O'Fallon, MO with the most Weekend Rn job openings:

Weekend Rn jobs near you
Infographic showing various Weekend Rn job openings in O'Fallon, MO as of August 2026, with employment types broken down into 1% As Needed, 67% Full Time, 27% Part Time, 4% Contract, and 1% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $84,714 per year, or $40.7 per hour.

RN, Weekend, Nights, FT

Mercy

Saint Louis, MO

$5.0K/wk

Full-time, Other

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago

New

Mercy rating

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

605th of 887 rated healthcare providers

Job description

Find your calling at Mercy!Utilizes the Mercy Nursing Conceptual Framework and nursing process to provide patient care. Maintains professional accountability for provision of patient care for the assigned patients. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information.Position Details:
Registered Nurse (RN) – Med Surg 5W

New Grads and Experienced Nurses Welcome!

Location: Mercy Hospital South - 10010 Kennerly Rd, St. Louis, Missouri 63128

Schedule: Full-Time | 36 hours/week

Shift: Weekend, Night Shift | 7:00PM-7:30AM

Sign-On Bonus:

  • Experienced Nurses: Up to $10,000

  • New Graduate Nurses (less than 1 year of experience): Up to $5,000

About the Unit — Med Surg 5W

Med Surg 5W cares for adult medical patients with diagnoses such as small bowel obstructions, respiratory infections, cellulitis, diverticulitis, and pneumonia. This unit provides an excellent environment to strengthen core Med Surg skills, enhance assessment abilities, and manage patients with diverse medical needs.

Overview

Utilizes the nursing process to provide patient care. Maintains professional accountability for provision of patient care for the assigned patients. Evaluates the overall effectiveness of care provided by other direct care givers. Coordinates the patient care in conjunction with other departments. Maintains patient rights and confidentiality of patient information. Performs duties and responsibilities in a manner consistent with our mission, values, and mercy service standards.

Qualifications

Education: Graduate of an accredited school of nursing with one of the following:

  • Associate Degree in Nursing

  • Nursing Diploma

  • Bachelor of Science in Nursing (BSN)

Licensure: Must hold and maintain a current Registered Nurse (RN) license in the state of Missouri or possess compact licensure, in accordance with state board of nursing regulations.

Experience: Previous hospital experience is preferred and may be required depending on the unit.

Certifications:

  • Required: Basic Life Support (BLS) certification through the American Heart Association, or completion within 30 days of hire.

Preferred Qualifications

  • Education: BSN preferred

  • Licensure: Additional state licensure or specialty certifications preferred

  • Experience: Prior experience in specialty area or similar clinical setting

Physical Requirements

  • Ability to push, pull, and lift up to 50 lbs. regularly

  • Prolonged standing and walking throughout the shift

  • Ability to grip, reach, bend, kneel, twist, and squat as needed to perform nursing duties

Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.

Powered by SonicJobs (an advertiser on Veritone). By applying, you consent to share your data with SonicJobs and the employer. Veritone or SonicJobs does not store or use your application data beyond facilitating the application.
See Mercy Terms & Conditions at and Privacy Policy at and SonicJobs Privacy Policy at and Terms of Use at Category:Healthcare, Keywords:Registered Nurse (RN), Location:St. Louis, MO-63110

What Mercy employees say

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827

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