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Weekend Rn Jobs in Missouri (NOW HIRING)

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Weekend Rn information

See Missouri salary details

$24

$37

$63

How much do weekend rn jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for weekend rn in Missouri is $37.72, according to ZipRecruiter salary data. Most workers in this role earn between $29.94 and $43.54 per hour, depending on experience, location, and employer.

What is a Weekend RN?

A Weekend RN is a registered nurse who primarily works during the weekends, often covering shifts on Saturdays and Sundays. These nurses provide patient care, administer medications, monitor patient progress, and collaborate with doctors and other healthcare staff. Weekend RNs may work in hospitals, nursing homes, or other healthcare facilities, and their schedules are designed to ensure continuous high-quality care throughout the week. Weekend shifts can sometimes offer higher pay rates or shift differentials due to the non-traditional hours.

What does a Weekend RN do?

As a weekend RN, you take shifts on the weekend when other nurses are unavailable, allowing hospitals and other care facilities to provide continuity of care and remain open 24/7. This is usually a part-time position, with most weekend RN's working two 8-12 hour shifts Saturday-Sunday each week. Some facilities also count Friday as a weekend day and offer a three-shift schedule instead. In this role, you may make patient visits, answer telephone calls to provide remote healthcare and address any medical emergencies that occur during your shift as a weekend nurse. As an RN, weekend work usually focuses on hospitals and hospice facilities, but you may find positions that involve traveling to visit patients outside of a clinical setting.

What are the key skills and qualifications needed to thrive as a Weekend RN, and why are they important?

To thrive as a Weekend RN, you need current RN licensure, strong clinical assessment skills, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are often required. Excellent time management, adaptability, and communication skills are essential for managing patient care during typically higher-acuity weekend shifts. These competencies ensure patient safety, efficient care delivery, and effective teamwork when staffing levels and resources may be limited.

What are some unique challenges and rewards of working as a Weekend RN compared to a standard weekday nursing position?

Weekend RNs often face a distinct set of challenges, including managing higher patient-to-nurse ratios and handling more acute or urgent cases, as there may be fewer staff and support services available on weekends. However, this role also offers unique rewards, such as greater autonomy, opportunities to hone critical thinking and decision-making skills, and often a more flexible schedule or additional compensation. Weekend RNs typically collaborate closely with a dedicated core team, fostering strong teamwork and communication. This experience can be valuable for career advancement, as it demonstrates adaptability and strong clinical competence in a fast-paced environment.

What is the difference between Weekend Rn vs Weekend Lpn?

AspectWeekend RnWeekend Lpn
Required CredentialsRegistered Nurse license (RN)Licensed Practical Nurse license (LPN)
Work EnvironmentHospitals, clinics, long-term care facilitiesLong-term care, nursing homes, clinics
Employer & Industry UsageHospitals, healthcare agenciesLong-term care facilities, nursing homes
Common Search & Comparison IntentUnderstanding RN roles on weekendsUnderstanding LPN roles on weekends

Weekend Rn and Weekend Lpn roles differ mainly in credentials, with RNs holding a registered nurse license and LPNs holding a practical nurse license. RNs typically perform more complex medical tasks and have broader responsibilities, while LPNs focus on basic patient care. Both roles are common in healthcare settings that require weekend coverage, but RNs generally have more advanced training and scope of practice.

What are the most commonly searched types of Rn jobs in Missouri?

The most popular types of Rn jobs in Missouri are:

What cities in Missouri are hiring for Weekend Rn jobs?

Cities in Missouri with the most Weekend Rn job openings:

Infographic showing various Weekend Rn job openings in Missouri as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 25% Part Time, 5% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $78,464 per year, or $37.7 per hour.

Registered Nurse (RN)

Four Seasons Living Center

Sedalia, MO

$50/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 27 days ago


Job description

Weekend RN needed- $50/hr

Schedule (7p-7a) Rotate Friday, Saturday, and Sundays

$10,000 Bonus

We are seeking individuals with genuine empathy and patience to help care for our residents’ needs. Applicants must have a caring approach and be willing to care for the needs of patients and the team. Pillars for successful employment are work ethic, integrity, and competence.


Job Responsibilities and Duties:
  • Assess patients’ health needs and develop and implement care plans

  • Administer medications and treatments as prescribed

  • Monitor patients’ vital signs and report any changes to the appropriate staff member

  • Communicate with patients and families to provide education and support

  • Collaborate with other healthcare professionals to coordinate care and ensure continuity of treatment

  • Document patients’ progress and outcomes using electronic medical records

  • Stay up-to-date with current research and best practices in nursing

  • Participate in professional development opportunities to maintain and improve skills

  • Other duties as assigned

Requirements:
  • Current unencumbered state license as a Registered Nurse

  • Minimum of 1 year of experience as a Registered Nurse preferred

  • Excellent communication and interpersonal skills

  • Ability to work collaboratively with other healthcare professionals

  • Strong problem-solving and critical thinking skills

Benefits:
  • Health Insurance

  • Dental Insurance

  • Disability Insurance

  • Vision Insurance

  • Employee Assistance Program

  • 401(k)

  • Life Insurance

  • Paid Time Off

Additional Benefits:
  • Telemedicine: $0 co-pay for telemedicine appointments, providing easy access to medical consultations from the comfort of your home.

  • Unlimited Assistance: Receive unlimited support for legal, financial, childcare, elder care, and more—designed to support your personal and family well-being.

  • Mayo Clinic Programs: Access exclusive programs from the Mayo Clinic, including resources for workouts, lifestyle, mental health, and diet to promote a balanced and healthy lifestyle.

These additional benefits are available to you without reducing your take-home pay!

We only accept resumes and applications submitted directly through our Applicant Tracking System for posted positions. We do not accept unsolicited resumes from third-party agencies, recruiters, or staffing firms. Company employees and hiring managers are not authorized to enter into agreements or otherwise bind the company with respect to recruiting services. Any resumes submitted without a signed written agreement by the Executive Vice President of Recruitment will be considered unsolicited, and no fees will be owed.