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Weekend Nurse Practitioner Jobs in Iowa (NOW HIRING)

Matrix Providers

Nurse Practitioner (NP)

Cedar Rapids, IA · On-site

$54 - $58.59/hr

Nurse Practitioner (NP) Matrix Providers is hiring a Nurse Practitioner (NP) to join our team of talented medical professionals to conduct one-time, non-treatment Veteran Disability Exams in ...

ChildServe

Nurse Practitioner (PRN)

Johnston, IA · On-site

Nurse Practitioner (PRN) Nurse (ARNP, RN, LPN) Johnston, Iowa Apply Description Child Serve is ... C all rotation after hours and weekend s is not required for this PRN role, but there are ...

Matrix Providers

$54 - $58.59/hr

Matrix Providers is hiring a Nurse Practitioner (NP) to join our team of talented medical professionals to conduct one-time, non-treatment Veteran Disability Exams in Cedar Rapids, IA. * Employment ...

St Croix Hospice

Nurse Practitioner (NP)

Hiawatha, IA · On-site

The Nurse Practitioner plays a key role in supporting patients and their families during advanced illness by providing skilled medical care and calm, compassionate guidance. They help families ...

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Weekend Nurse Practitioner information

See Iowa salary details

$39K

$122.4K

$187.9K

How much do weekend nurse practitioner jobs pay per year?

As of Aug 26, 2026, the average yearly pay for weekend nurse practitioner in Iowa is $122,381.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,400.00 and $140,900.00 per year, depending on experience, location, and employer.

What is a weekend nurse practitioner?

Weekend Nurse Practitioners are advanced practice registered nurses (APRNs) who primarily work on weekends, providing healthcare services similar to those of physicians. They assess patients, diagnose illnesses, prescribe medications, and develop treatment plans during weekend shifts in settings like hospitals, urgent care centers, or clinics. Their role helps ensure continuous patient care outside of regular weekday hours, addressing urgent and routine health needs when other providers may be unavailable.

What does a weekend nurse practitioner do?

A weekend nurse practitioner, or weekend NP, provides healthcare services for patients during a weekend shift. Some weekend NPs only work on the weekends, while others have a varied schedule and work during the week depending on staffing needs. As a nurse practitioner, you provide primary care to patients. As part of your responsibilities, you may examine and diagnose patients, prescribe medication, and offer treatment. You may perform your duties independently or under the supervision of a physician. Weekend NP positions are available in hospitals, clinics, urgent care facilities, nursing homes, and other health care settings that operate during the weekends.

What are the key skills and qualifications needed to thrive as a weekend nurse practitioner?

To thrive as a Weekend Nurse Practitioner, you need advanced clinical skills, diagnostic abilities, and a master's or doctoral degree in nursing along with national certification and state licensure. Familiarity with electronic health records (EHRs), telehealth platforms, and point-of-care testing tools is often required. Outstanding communication, time management, and independent decision-making skills are crucial for providing care during off-hours with limited resources. These competencies ensure safe, efficient, and high-quality patient care when oversight may be reduced and urgent needs arise.

What are the typical responsibilities and work expectations for a weekend nurse practitioner?

As a Weekend Nurse Practitioner, you are often responsible for providing primary or urgent care services during weekends, which may include assessing patients, diagnosing conditions, prescribing medications, and coordinating care with physicians and other healthcare staff. You may also handle walk-in patients, manage acute cases, and ensure continuity of care for patients admitted over the weekend. The role often requires autonomy, adaptability, and strong decision-making skills, as weekend coverage may involve fewer on-site resources and increased reliance on your clinical judgment. Collaboration with nurses, support staff, and on-call physicians is common, and effective teamwork is essential for delivering quality patient care in this setting.

What is the difference between Weekend Nurse Practitioner vs Weekend Physician Assistant?

AspectWeekend Nurse PractitionerWeekend Physician Assistant
CredentialsMaster's or Doctoral degree in Nursing, Nurse Practitioner certificationMaster's degree in Physician Assistant Studies, PA certification
Work EnvironmentClinics, urgent care, primary care settings, often in outpatient facilitiesUrgent care, emergency departments, outpatient clinics, similar settings
Employer & IndustryHospitals, clinics, healthcare organizations, outpatient facilitiesHospitals, urgent care centers, clinics, healthcare organizations

Weekend Nurse Practitioners and Weekend Physician Assistants share similar work environments and employer types, often working in outpatient and urgent care settings. The main difference lies in their credentials and certification pathways, with NPs holding advanced nursing degrees and PAs completing physician assistant programs. Both roles are vital for providing healthcare services during weekends, offering flexibility and extended care hours.

Can a weekend nurse practitioner work 3 days a week?

A weekend nurse practitioner can work three days a week if the employer's schedule and state regulations permit it. Many nurse practitioners have flexible schedules, but they must meet licensing, credentialing, and practice scope requirements, which can vary by location and employer policies.

What is a good side hustle for a weekend nurse practitioner?

A weekend nurse practitioner can pursue telehealth consulting, providing virtual patient care or health advice outside regular hours. They can also offer health coaching, wellness assessments, or freelance medical writing, leveraging their clinical skills and certifications to generate additional income on weekends.
More about Weekend Nurse Practitioner jobs

What are the most commonly searched types of Nurse Practitioner jobs in Iowa?

The most popular types of Nurse Practitioner jobs in Iowa are:

What are popular job titles related to Weekend Nurse Practitioner jobs in Iowa?

For Weekend Nurse Practitioner jobs in Iowa, the most frequently searched job titles are:

What job categories do people searching Weekend Nurse Practitioner jobs in Iowa look for?

The top searched job categories for Weekend Nurse Practitioner jobs in Iowa are:

What cities in Iowa are hiring for Weekend Nurse Practitioner jobs?

Cities in Iowa with the most Weekend Nurse Practitioner job openings:

Weekend Nurse Practitioner jobs near you
Infographic showing various Weekend Nurse Practitioner job openings in Iowa as of August 2026, with employment types broken down into 80% Full Time, 10% Part Time, and 10% Temporary. Highlights an 100% In-person job distribution, with an average salary of $122,381 per year, or $58.8 per hour.

Locum Cardiothoracic Surgery Nurse Practitioner | Mason City, Iowa

NP Inc

Mason City, IA • On-site

Other

Posted 12 days ago

Job description

Locum Cardiothoracic Surgery Nurse Practitioner | Mason City, Iowa

We're seeking an experienced Cardiothoracic Surgery Nurse Practitioner for an exciting locum opportunity at a Level II Trauma Center in Mason City, Iowa. If you have CT surgery and endoscopic vein harvesting (EVH) experience, this is an outstanding opportunity with premium compensation and ongoing scheduling flexibility.

Location: Mason City, Iowa Position: Locum Nurse Practitioner – Cardiothoracic Surgery

Practice Highlights

Level II Trauma Center Cardiothoracic Surgery & EVH experience required Monday–Friday: Clinic (8 AM–5 PM) plus night call Weekend Coverage: 24-hour call Call Rotation: 1:2 Approximately 125 CABG cases annually Collaborative cardiovascular surgery team

Current Coverage Needs

September 7–11 (8 AM–5 PM)

September 28 – October 2 (8 AM–5 PM)

October 5–11 Day shifts (8 AM–5 PM) Night call 24-hour call October 10 & 11

November 23–28 Day shifts (8 AM–5 PM) Night call 24-hour call November 26 & 28

December 21–31 Day shifts (8 AM–5 PM) Night call 24-hour call December 26 & 27

Additional ongoing coverage available

Candidate Requirements

Board Certified Nurse Practitioner Active Iowa License ACLS & BLS Certifications Minimum 2 years of Cardiothoracic Surgery experience EVH experience required Ability to cover at least some of the requested dates Clean malpractice/background history Current NPDB Self-Query Report (within 30 days)

If you're an experienced CT Surgery NP looking for premium locum rates and ongoing opportunities, we'd love to speak with you!

Apply