This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics ...
Downstream Development Associate II
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Downstream Development Associate II
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Downstream Development Associate II
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Downstream Development Associate II
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Downstream Development Associate II
Bothell, WA ยท On-site
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Downstream Development Associate II
Bothell, WA ยท On-site
$38 - $45/hr
Prepares purified protein product to support upstream process development and supply further downstream process development activities. * Performs analytical methods, such as UV-visible ...
Lead a diverse group of scientists responsible for the development of early and late-stage upstream perfusion and intensified processes for biotherapeutics manufacturing utilizing statistical ...
Lead a diverse group of scientists responsible for the development of early and late-stage upstream perfusion and intensified processes for biotherapeutics manufacturing utilizing statistical ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Senior Scientist I, Purification Process Development Location: Redmond, WA Reports to: Director ... areas (upstream and analytical sciences). * Experience working in a cGMP or clean room setting ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate cross-functionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate cross-functionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate cross-functionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate cross-functionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate crossfunctionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present findings ...
Associate Scientist, Cell Line Development
Seattle, WA ยท On-site
$78K - $82K/yr
Collaborate crossfunctionally with upstream process development, analytics, and data science teams to ensure seamless program execution. * Troubleshoot experiments, analyze data, and present findings ...
Senior Scientist, Cell Science
Redmond, WA ยท On-site
$90K - $140K/yr
Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred. * Demonstrated expertise in advanced ...
Senior Scientist, Cell Science
Redmond, WA ยท On-site
$90K - $140K/yr
Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred. * Demonstrated expertise in advanced ...
Senior Scientist, Cell Science
Redmond, WA ยท On-site
$90K - $140K/yr
Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred. * Demonstrated expertise in advanced ...
Quick apply
Senior Scientist, Cell Science
Redmond, WA ยท On-site
$90K - $140K/yr
Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred. * Demonstrated expertise in advanced ...
Experience with viral vector process development, including upstream production (e.g., suspension culture, transfection parameters, bioreactor scale-up) and downstream purification and concentration ...
Experience with viral vector process development, including upstream production (e.g., suspension culture, transfection parameters, bioreactor scale-up) and downstream purification and concentration ...
Experience with viral vector process development, including upstream production (e.g., suspension culture, transfection parameters, bioreactor scaleup) and downstream purification and concentration ...
Experience with viral vector process development, including upstream production (e.g., suspension culture, transfection parameters, bioreactor scaleup) and downstream purification and concentration ...
Director/Senior Director of Analytical
Redmond, WA ยท On-site
$190K - $280K/yr
... development and GMP manufacturing. The role is responsible for integration of analytical workflows with upstream and downstream processes and is accountable for analytical method transfer to the ...
Quick apply
Director/Senior Director of Analytical
Redmond, WA ยท On-site
$190K - $280K/yr
... development and GMP manufacturing. The role is responsible for integration of analytical workflows with upstream and downstream processes and is accountable for analytical method transfer to the ...
Upstream Process Development information
See Redmond, WA salary details
$21.27 - $23.15
4% of jobs
$23.15 - $25.04
5% of jobs
$26.27 is the 25th percentile. Wages below this are outliers.
$25.04 - $26.92
24% of jobs
The median wage is $28.08 / hr.
$26.92 - $28.81
27% of jobs
$30.69 is the 75th percentile. Wages above this are outliers.
$28.81 - $30.69
15% of jobs
$30.69 - $32.58
13% of jobs
$32.58 - $34.46
5% of jobs
$34.46 - $36.34
4% of jobs
$36.34 - $38.23
2% of jobs
$38.23 - $40.11
1% of jobs
$40.11 - $42
0% of jobs
$21
$29
$41
How much do upstream process development jobs pay per hour?
What are the key skills and qualifications needed to thrive in upstream process development?
What is the difference between Upstream Process Development vs Downstream Process Development?
| Aspect | Upstream Process Development | Downstream Process Development |
|---|---|---|
| Focus | Development of cell culture, fermentation, and bioreactor processes | Purification, filtration, and formulation of bioproducts |
| Skills & Credentials | Bioprocess engineering, molecular biology, biochemistry | Bioprocessing, chromatography, analytical chemistry |
| Work Environment | Laboratories, bioreactors, pilot plants | Purification facilities, labs, quality control |
| Industry Usage | Biotech, pharmaceutical manufacturing | Biotech, pharmaceutical manufacturing |
Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.
What are some common challenges faced in upstream process development and how do teams typically address them?

Full-time
Medical, Dental, Vision, Life, Retirement, PTO
Re-posted 14 hours ago
Job description
Location: Redmond, WA
Reports To: Director, Process Sciences
About Us:
At Just-Evotec, we believe that curiosity is the spark that drives innovation and success. As a forward-thinking team, we thrive on challenging the status quo, learning from each other, and pushing the boundaries of what's possible. We're on a mission to create a place where curiosity isn't just encouraged, it's celebrated.
Are you someone who asks questions, seeks answers, and isn't afraid to go deeper? #BeCureious with us and see where your curiosity can take you!
The Role:
We're seeking an enthusiastic and hardworking team member who is passionate about expanding worldwide access to biotherapeutics through the advancement of continuous bioprocessing technology and mammalian cell culture processes.
This person will join a fast-paced, collaborative, and multidisciplinary team to support upstream process development at the bench and pilot scale for the advancement of low-cost biotherapeutics manufacturing. This position will oversee upstream process optimization, technology transfer, and process characterization for hybrid and end-to-end continuous processes.
The successful candidate will be detail-oriented, self-motivated, and efficient in completing hands-on laboratory tasks, and experience with bioreactor equipment operation and maintenance, lab management, and organizing workspace and tasks are required. The ideal candidate will have strong scientific group management and leadership skills as well as a proven track record of a deep understanding of upstream process development for clinical and commercial therapeutic proteins. Strong written and verbal communication skills are required as well as experience in client and multi-site communication. Finally, the ideal candidate is curious, creative, engaged, and the type who works well independently and in teams while constantly looking for ways to advance scientific processes and improve technology.
What You'll Do:
- Leading a mammalian cell culture department with a diverse group of scientists encompassing all aspects of upstream process development, characterization, and validation as well as technology transfer to cGMP manufacturing for continuous processes.
- Leading highly complex projects and investigations by integrating deep knowledge of upstream process development and broad knowledge of project work with knowledge of multiple functional areas.
- Collaborating across the organization to accelerate clinical development timelines while reducing development costs.
- Driving technology development for process intensification and continuous manufacturing to reduce manufacturing costs and footprint through improvements in cell culture productivity, control of product quality, and data management while working with vendors and external partners as well as influencing the biologics industry.
- Serving as a Project Team Lead within the process development organization to execute on client projects that involve multiple functional areas and the full range of regulatory stages.
- Serving as an internal technical resource for cGMP manufacturing and Process Design as well as a resource and subject matter expert for external clients and partners for perfusion bioreactor processes (small scale models, process transfer, and scale up) and authoring CMC regulatory sections.
- Clearly and effectively communicating scientific information, experimental plans, and data to internal project teams, cross-functional area teams, senior management, external clients, vendors, and technology development collaborators as well as the external scientific community such as regulatory agencies, review boards, publications, and conferences.
- Managing staff, training, capital resources, and planning within the department while supporting multiple client projects at various stages of process development and characterization.
- Other tasks as assigned.
Who You Are:
- BS/MS in Engineering, Biochemistry, Biology, or related field with 15+ years of experience or Ph.D. in Engineering, Biochemistry, Biology, or related field with 9+ years of experience.
- Expertise in mammalian cell culture and perfusion bioreactor technology development, transfer to cGMP manufacturing plants, and authoring CMC sections of regulatory filings.
- Experience with commercial process development, process characterization, and validation.
- Expertise in design of experiments (DOE) and statistical analysis.
- Experience in training, mentoring, and supervising team members as well as leading upstream development teams for multiple external client projects and collaborations and internal technology development initiatives.
- Experience with high throughput cell culture (e.g. deep-well plate assays, robotic systems such as Ambr) as well as other functional areas (purification and analytical sciences) is a plus.
Pluses:
- Experience analyzing data in tools such as JMP, R, or Python.
- Experience working in a cGMP or clean room setting (this job is non-GMP but knowledge of GMP is helpful for process/tech transfer activities).
Why Join Us:
- Growth Opportunities: We're a company that believes in continuous learning and development. Whether it's professional courses, mentorship, or new projects, we'll help you grow.
- Inclusive Culture: We're committed to building a diverse and inclusive environment where everyone's voice is valued, and curiosity is encouraged.
- Innovative Projects: You'll have the chance to work on groundbreaking initiatives and cutting-edge technology in an atmosphere where your curiosity is the key to success.
- A Place for Big Ideas: We don't just talk about thinking outside the box, we throw the box away. If you've got ideas, we want to hear them.
Are You Still Curious?
If you've read this far, then chances are you've got a curious mind, just like us. So, what are you waiting for? Take the leap and apply today. We can't wait to see where your curiosity leads you and how it will shape the future of Just-Evotec.
The base pay range for this position at commencement of employment is expected to be $154,000 to $180,000; Base salary offered may vary depending on individual's skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.
Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.