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Upstream Process Development Jobs in Raleigh, NC

Upstream Rehabilitation

Physical Therapist

Apex, NC · On-site

$1.2K - $1.6K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process.

Upstream Rehabilitation , Inc.

Physical Therapist

Apex, NC · On-site

$1.2K - $1.6K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

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All JobsUpstream Process Development JobsUpstream Process Development Jobs in Raleigh, NC

Upstream Process Development information

See Raleigh, NC salary details

$18

$25

$36

How much do upstream process development jobs pay per hour?

As of Jul 13, 2026, the average hourly pay for upstream process development in Raleigh, NC is $25.77, according to ZipRecruiter salary data. Most workers in this role earn between $22.88 and $27.12 per hour, depending on experience, location, and employer.

What jobs pay 500,000 a year in the US?

In the field of Upstream Process Development, senior roles such as Director or Vice President can reach or exceed $500,000 annually, especially with bonuses and stock options. These positions typically require extensive experience, advanced degrees, and leadership skills in biopharmaceutical or biotech industries. High compensation is often associated with managerial responsibilities, strategic decision-making, and overseeing large teams or projects.

What are the key skills and qualifications needed to thrive in Upstream Process Development, and why are they important?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are common upstream jobs?

Common upstream process development jobs include roles such as upstream process scientist, bioprocess engineer, and fermentation scientist. These positions focus on developing and optimizing the early stages of biopharmaceutical production, often requiring knowledge of cell culture, bioreactor operation, and process scale-up. Skills in laboratory techniques, process analytical technology, and regulatory compliance are also important in these roles.

What biology jobs pay over $100k?

In upstream process development, senior roles such as Process Development Managers, Principal Scientists, and Regulatory Affairs Directors often have salaries exceeding $100,000. These positions typically require advanced degrees, extensive industry experience, and expertise in bioprocessing, quality control, or regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What is upstream process development?

Upstream process development involves designing and optimizing the initial stages of biopharmaceutical production, such as cell culture and fermentation, to produce target biological products. It requires knowledge of bioprocessing, cell biology, and often involves working with bioreactors and process control systems to ensure consistent, high-quality output.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.
What are popular job titles related to Upstream Process Development jobs in Raleigh, NC? For Upstream Process Development jobs in Raleigh, NC, the most frequently searched job titles are:
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Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Raleigh, NC as of July 2026, with employment types broken down into 80% Full Time, and 20% Part Time. Highlights an 100% In-person job distribution, with an average salary of $53,611 per year, or $25.8 per hour.
Physical Therapist Assistant

Physical Therapist Assistant

Upstream Rehabilitation

Holly Springs, NC • On-site

$28 - $35/hr

Other

Medical, Dental, Vision, Retirement, PTO

Re-posted 12 days ago

Upstream Rehabilitation rating

6.3

Company rating: 6.3 out of 10

Based on 68 frontline employees who took The Breakroom Quiz

668th of 882 rated healthcare providers

Job description

Physical Therapist Assistant - Outpatient Orthopedics 

Grow Your Physical Therapist Assistant Career with Us! 

At Results Physiotherapy, part of the Upstream Rehabilitation network, you'll have the support, mentorship, and tools you need to thrive as a Physical Therapist Assistant (PTA) in a modern outpatient orthopedic setting. 

We're hiring full-time, part-time, and PRN PTAs who are passionate about helping patients recover movement and return to the activities they love. Whether you're a recent graduate or an experienced clinician, you'll find a collaborative environment, competitive pay, and a clear career path that grows with you. 

Why Clinicians Choose Results Physiotherapy: 

  • Competitive Physical Therapist Assistant rate: $28.00 - $35.00 / hour 
  • Achievable monthly clinical bonus program, over 90% of clinicians qualify 
  • 100% employer paid medical health insurance premium option available 
  • Dental and Vision insurance 
  • 401k with company match 
  • Generous PTO and paid holidays 
  • Structured onboarding and mentorship for new-grad PTAs  
  • Robust continuing education and CEU opportunities through Upstream - with annual allowance! 
  • Pathways for professional development and long-term career advancement 
  • Modern clinical technology that reduces documentation time so you can focus on patients 
  • A supportive team and leadership invested in your success 

What You'll Do as a Physical Therapist Assistant 

  • Deliver hands-on, evidence-based care under the supervision of a licensed Physical Therapist 
  • Help patients improve mobility, strength, and function through individualized treatment plans 
  • Track patient progress and collaborate closely with your clinical team 
  • Foster positive relationships with patients, providers, and your local community 
  • Continue your professional growth through Upstream's mentorship and learning programs 

Qualifications 

  • Graduate of an accredited Physical Therapist Assistant program 
  • Active North Carolina PTA license (or eligibility)  

A Better Place to Build Your PTA Career 

When you join Upstream Rehabilitation, you get the strength of a national network with the feel of a local clinic. 

Our central support teams handle the administrative work, so you can focus on what matters most - the patient in front of you. With a network of over 1,200 clinics coast-to-coast across 26 brand partners, we lead the industry in quality outcomes, leveraging data, technology, and innovation to reduce paperwork and give you more time for care. 

You'll be part of a fantastic group of clinicians who shape our culture, create a positive work environment, and know how to have fun along the way. It's easy to see why so many Physical Therapists choose to grow their careers with Upstream. 

Estimated pay ranges listed above are based on several factors including but not limited to your pay class, experience, background and geographic location of the clinic 

Benefits and eligibility are dependent on employment status and pay class (full-time, part-time, or PRN). Specific details will be provided during the hiring process. 

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