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Upstream Process Development Jobs in Bothell, WA

Just - Evotec Biologics

Process Engineer II

Seattle, WA · On-site

$86K - $90K/yr

The PE II will then execute upstream and/or downstream manufacturing operations they had a hand in ... Growth Opportunities : We're a company that believes in continuous learning and development.

Evotec

Process Engineer II

Seattle, WA · On-site

$86K - $90K/yr

The PE II will then execute upstream and/or downstream manufacturing operations they had a hand in ... Growth Opportunities : We're a company that believes in continuous learning and development.

Evotecgroup

Process Engineer II

Seattle, WA · On-site

$86K - $90K/yr

The PE II will then execute upstream and/or downstream manufacturing operations they had a hand in ... Growth Opportunities : We're a company that believes in continuous learning and development.

Evotec

Process Engineer II

Seattle, WA

$86K - $90K/yr

The PE II will then execute upstream and/or downstream manufacturing operations they had a hand in ... Growth Opportunities : We're a company that believes in continuous learning and development.

Evotec

Principal Process Engineer

Redmond, WA

What You'll Do: * Develop strategies for the design and development of new and existing ... Understanding of upstream cell culture expansion and processing operations, including perfusion ...

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Upstream Process Development information

See Bothell, WA salary details

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How much do upstream process development jobs pay per hour?

As of Jul 14, 2026, the average hourly pay for upstream process development in Bothell, WA is $29.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.35 and $31.15 per hour, depending on experience, location, and employer.

What jobs pay 500,000 a year in the US?

In the field of Upstream Process Development, senior roles such as Director or Vice President can reach or exceed $500,000 annually, especially with bonuses and stock options. These positions typically require extensive experience, advanced degrees, and leadership skills in biopharmaceutical or biotech industries. High compensation is often associated with managerial responsibilities, strategic decision-making, and overseeing large teams or projects.

What are the key skills and qualifications needed to thrive in Upstream Process Development, and why are they important?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are common upstream jobs?

Common upstream process development jobs include roles such as upstream process scientist, bioprocess engineer, and fermentation scientist. These positions focus on developing and optimizing the early stages of biopharmaceutical production, often requiring knowledge of cell culture, bioreactor operation, and process scale-up. Skills in laboratory techniques, process analytical technology, and regulatory compliance are also important in these roles.

What biology jobs pay over $100k?

In upstream process development, senior roles such as Process Development Managers, Principal Scientists, and Regulatory Affairs Directors often have salaries exceeding $100,000. These positions typically require advanced degrees, extensive industry experience, and expertise in bioprocessing, quality control, or regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What is upstream process development?

Upstream process development involves designing and optimizing the initial stages of biopharmaceutical production, such as cell culture and fermentation, to produce target biological products. It requires knowledge of bioprocessing, cell biology, and often involves working with bioreactors and process control systems to ensure consistent, high-quality output.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.
What are popular job titles related to Upstream Process Development jobs in Bothell, WA? For Upstream Process Development jobs in Bothell, WA, the most frequently searched job titles are:
What job categories do people searching Upstream Process Development jobs in Bothell, WA look for? The top searched job categories for Upstream Process Development jobs in Bothell, WA are:
What cities near Bothell, WA are hiring for Upstream Process Development jobs? Cities near Bothell, WA with the most Upstream Process Development job openings:
Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Bothell, WA as of July 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $61,652 per year, or $29.6 per hour.
Process Engineer II

Process Engineer II

Just - Evotec Biologics

Seattle, WA • On-site

$86K - $90K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 6 days ago

Job description

Job Title: Process Engineer II
Location: Seattle, WA
About Us:
At Just-Evotec, we believe that curiosity is the spark that drives innovation and success. As a forward-thinking team, we thrive on challenging the status quo, learning from each other, and pushing the boundaries of what's possible. We're on a mission to create a place where curiosity isn't just encouraged, it's celebrated.
Are you someone who asks questions, seeks answers, and isn't afraid to go deeper? #BeCureious with us and see where your curiosity can take you!
The Role:
This role requires close collaboration with multi-disciplinary project/technical teams as we work together to define the future of biotherapeutics and embrace the challenge of innovation.
Under direct/moderate supervision, job responsibilities encompass the transfer of novel purification processes from model to manufacturing scale. Process engineers will work closely with scientists and engineers to develop manufacturing processes for novel biotherapeutics. The PE II will then execute upstream and/or downstream manufacturing operations they had a hand in building. The role will work with disposable based manufacturing equipment and be involved in upstream manufacturing operations including performing aseptic operations, shake flask cell expansion process, bioreactor operations and media preparation; and downstream manufacturing operations including continuous protein capture, chromatography polishing steps, and drug formulation and fill. The staff member may also participate in technology transfer, troubleshooting, GMP documentation revision and deviation investigations.
The staff member is expected to comply and follow written procedures for safety requirements, cGMP Practices, Standard Operating Procedures, and manufacturing documentation.
Who You Are:
  • Bachelor's degree in biological science or engineering with 3-5 years of relevant experience.
  • Candidate must possess strong focus on quality and attention to detail.
  • Possess effective task/time management organizational skills.
  • Capacity to develop solutions to technical issues of moderate scope.
  • Ability to organize, analyze/interpret, and effectively communicate individual results.
  • Motivated, self-starter with strong mechanical aptitude.
  • Good interpersonal, team, and communication skills are a must.
  • Excellent oral and written communication skills.

Preferred Qualifications:
  • Knowledge of cGMP requirements to ensure compliance.
  • Understanding of equipment, operations, and engineering principles used to manufacture biotherapeutics.
  • Experience in cell culture principles and aseptic technique.
  • Experience in purification principles and operations.
  • Experience with disposable-based processing equipment is a plus.
  • Experience in technology and/or process transfer for early-stage clinical manufacturing.
  • Ability to solve technical problems of moderate scope.

Why Join Us:
  • Growth Opportunities: We're a company that believes in continuous learning and development. Whether it's professional courses, mentorship, or new projects, we'll help you grow.
  • Inclusive Culture: We're committed to building a diverse and inclusive environment where everyone's voice is valued, and curiosity is encouraged.
  • Innovative Projects: You'll have the chance to work on groundbreaking initiatives and cutting-edge technology in an atmosphere where your curiosity is the key to success.
  • A Place for Big Ideas: We don't just talk about thinking outside the box-we throw the box away. If you've got ideas, we want to hear them.

Are You Still Curious?
If you've read this far, then chances are you've got a curious mind, just like us. So, what are you waiting for? Take the leap and apply today. We can't wait to see where your curiosity leads you and how it will shape the future of Just-Evotec.
Let your curiosity guide your career #BeCurious and explore the endless possibilities at Just-Evotec!
The base pay range for this position at commencement of employment is expected to be $86,250 to $90,000; Base salary offered may vary depending on individual's skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.
Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

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