Upstream Principal CQV Engineer Responsibilities:Upstream System Leadership * Serve as the ... Gain a thorough understanding of system design by reviewing engineering documentation, P&IDs, and ...
Upstream Principal CQV Engineer Responsibilities:Upstream System Leadership * Serve as the ... Gain a thorough understanding of system design by reviewing engineering documentation, P&IDs, and ...
Upstream Principal CQV Engineer Responsibilities:Upstream System Leadership * Serve as the ... Ensure alignment with quality, automation, and engineering teams on critical parameters and ...
Quick apply
Upstream Principal CQV Engineer Responsibilities:Upstream System Leadership * Serve as the ... Ensure alignment with quality, automation, and engineering teams on critical parameters and ...
6242 - Upstream Principal CQV Engineer / Lead Validation Engineer
Holly Springs, NC · On-site
$107K - $168K/yr
Upstream Principal CQV Engineer Responsibilities: Upstream System Leadership * Serve as the ... Ensure alignment with quality, automation, and engineering teams on critical parameters and ...
6242 - Upstream Principal CQV Engineer / Lead Validation Engineer
Holly Springs, NC · On-site
$107K - $168K/yr
Upstream Principal CQV Engineer Responsibilities: Upstream System Leadership * Serve as the ... Ensure alignment with quality, automation, and engineering teams on critical parameters and ...
CQV Lead, Upstream
Holly Springs, NC · On-site
$88K - $116K/yr
Title - CQV Lead, Upstream Location: Holly Springs, North Carolina Visa - OPEN NEED LEAD CANDIDATE ONLY WITH LINKEDIN PROFILE seeking a highly experienced CQV (Commissioning, Qualification, and ...
Quick apply
CQV Lead, Upstream
Holly Springs, NC · On-site
$88K - $116K/yr
Title - CQV Lead, Upstream Location: Holly Springs, North Carolina Visa - OPEN NEED LEAD CANDIDATE ONLY WITH LINKEDIN PROFILE seeking a highly experienced CQV (Commissioning, Qualification, and ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... Process Engineer - Solution Prep, Upstream, and Downstream What you will do In this vital role you ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... Process Engineer - Solution Prep, Upstream, and Downstream What you will do In this vital role you ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... ProcessEngineer-Solution Prep,Upstream, andDownstream What youwill do In this vital role you will ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... ProcessEngineer-Solution Prep,Upstream, andDownstream What youwill do In this vital role you will ...
Senior Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, NC · On-site
$90K - $116K/yr
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... Senior Process Engineer - Solution Prep, Upstream, and Downstream What you will do In this vital ...
Senior Process Engineer - Solution Prep, Upstream, and Downstream
Holly Springs, NC · On-site
$90K - $116K/yr
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... Senior Process Engineer - Solution Prep, Upstream, and Downstream What you will do In this vital ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... SeniorProcessEngineer-Solution Prep,Upstream,andDownstream What youwill do In this vital role you ...
Career Category Engineering Join Amgen's Mission of Serving Patients At Amgen, if you feel like you ... SeniorProcessEngineer-Solution Prep,Upstream,andDownstream What youwill do In this vital role you ...
Position Overview The Automation Engineer 3, DSM Upstream, will provide support to the Drug ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
Position Overview The Automation Engineer 3, DSM Upstream, will provide support to the Drug ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
Position Overview The Automation Engineer 3, DSM Upstream, will provide support to the Drug ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
Position Overview The Automation Engineer 3, DSM Upstream, will provide support to the Drug ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
The Automation Engineer 3, DSM Upstream, will provide support to the Drug Substance Manufacturing ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
The Automation Engineer 3, DSM Upstream, will provide support to the Drug Substance Manufacturing ... Bachelor's degree in Chemical, Electrical, or Mechanical Engineering or other relevant field * 5 ...
The Upstream Field Application Specialist is responsible for partnering with customers and sales ... Who you are * BS Degree in Life Science (Biology, Biochemistry, Chemistry) or Engineering and must ...
The Upstream Field Application Specialist is responsible for partnering with customers and sales ... Who you are * BS Degree in Life Science (Biology, Biochemistry, Chemistry) or Engineering and must ...
The Upstream Field Application Specialist is responsible for partnering with customers and sales ... Who you are * BS Degree in Life Science (Biology, Biochemistry, Chemistry) or Engineering and must ...
The Upstream Field Application Specialist is responsible for partnering with customers and sales ... Who you are * BS Degree in Life Science (Biology, Biochemistry, Chemistry) or Engineering and must ...
Sr. Open-Source Software Engineer - Apache Cassandra
Morrisville, NC · On-site
$114K - $151K/yr
Our Cassandra engineering team leads active work on Cassandra 6.0, owns releases across core and ecosystem subprojects, and drives upstream contributions that directly address production-scale ...
Sr. Open-Source Software Engineer - Apache Cassandra
Morrisville, NC · On-site
$114K - $151K/yr
Our Cassandra engineering team leads active work on Cassandra 6.0, owns releases across core and ecosystem subprojects, and drives upstream contributions that directly address production-scale ...
Our Cassandra engineering team leads active work on Cassandra 6.0, owns releases across core and ecosystem subprojects, and drives upstream contributions that directly address production-scale ...
Our Cassandra engineering team leads active work on Cassandra 6.0, owns releases across core and ecosystem subprojects, and drives upstream contributions that directly address production-scale ...
Sr. Open Source Software Engineer (Kafka)
Morrisville, NC · On-site
$114K - $151K/yr
This role connects deep upstream work, including binding committer authority, KIP-level design, and protocol-aware engineering, directly to production-scale outcomes in enterprise Kafka deployments.
New
Sr. Open Source Software Engineer (Kafka)
Morrisville, NC · On-site
$114K - $151K/yr
This role connects deep upstream work, including binding committer authority, KIP-level design, and protocol-aware engineering, directly to production-scale outcomes in enterprise Kafka deployments.
New
Process Engineering team member on capital projects. * Makes independent decisions within defined areas of responsibility. * Advances technical project proposals to senior management, following ...
Process Engineering team member on capital projects. * Makes independent decisions within defined areas of responsibility. * Advances technical project proposals to senior management, following ...
Front Line Manufacturing Manager - Upstream Bulk Drug Substance - Days What you will do Let's do ... Partner with Quality, Engineering, NPI, Supply Chain, Validation, and Site Leadership to enable ...
Front Line Manufacturing Manager - Upstream Bulk Drug Substance - Days What you will do Let's do ... Partner with Quality, Engineering, NPI, Supply Chain, Validation, and Site Leadership to enable ...
KBI: US - Process Engineer III
Durham, NC · On-site
You will apply sound scientific and engineering principles to successfully define upstream and downstream process equipment requirements, specifications and standards for facility fit, and assess ...
KBI: US - Process Engineer III
Durham, NC · On-site
You will apply sound scientific and engineering principles to successfully define upstream and downstream process equipment requirements, specifications and standards for facility fit, and assess ...
KBI: US - Process Engineer III
Durham, NC · On-site
You will apply sound scientific and engineering principles to successfully define upstream and downstream process equipment requirements, specifications and standards for facility fit, and assess ...
KBI: US - Process Engineer III
Durham, NC · On-site
You will apply sound scientific and engineering principles to successfully define upstream and downstream process equipment requirements, specifications and standards for facility fit, and assess ...
Upstream Engineering information
See Raleigh, NC salary details
$31.6K - $37.2K
9% of jobs
$37.2K - $42.7K
6% of jobs
$46.8K is the 25th percentile. Wages below this are outliers.
$42.7K - $48.3K
14% of jobs
$48.3K - $53.9K
10% of jobs
The median wage is $59.4K / yr.
$53.9K - $59.4K
12% of jobs
$59.4K - $65K
9% of jobs
$69.3K is the 75th percentile. Wages above this are outliers.
$65K - $70.6K
21% of jobs
$70.6K - $76.1K
5% of jobs
$76.1K - $81.7K
6% of jobs
$81.7K - $87.3K
4% of jobs
$87.3K - $92.8K
4% of jobs
$31.6K
$61.2K
$92.8K
How much do upstream engineering jobs pay per year?
What are some common challenges faced by upstream engineers when working on oil and gas exploration projects?
What is the difference between Upstream Engineering vs Reservoir Engineering?
| Aspect | Upstream Engineering | Reservoir Engineering |
|---|---|---|
| Required Credentials | Bachelor's in Petroleum Engineering or related field; often requires professional engineering license | Bachelor's in Petroleum Engineering, Reservoir Engineering, or Geosciences; often requires similar certifications |
| Work Environment | Field operations, drilling sites, and production facilities | Reservoir simulation labs, office-based analysis, and field data interpretation |
| Industry Usage | Exploration, drilling, and production of oil and gas | Reservoir performance analysis and recovery optimization |
Upstream Engineering focuses on the exploration, drilling, and production of oil and gas, involving field operations and equipment. Reservoir Engineering specializes in analyzing subsurface reservoirs to maximize hydrocarbon recovery through simulation and modeling. While both roles require similar educational backgrounds and certifications, their work environments and primary responsibilities differ significantly.
What is upstream engineering?
What are the key skills and qualifications needed to thrive as an Upstream Engineer, and why are they important?
- Aerospace Engineer Internship
- Chemical Engineering Intern
- Environmental Engineering Intern
- Biomedical Engineer Intern
- Internship Cosmetic Chemical Engineer
- Textile Engineering Internship
- Summer Autodesk Internships
- Quality Engineer Internship
- Environmental Engineer Internship
- Intern Assistant Orchestra Conductor
- Industrial Engineering Intern
- Part Time Mechanical Engineering Intern
- Internship Microchip Design Engineer
- Engineering Intern
- Part Time Engineering Internship
- Internship Microsoft Biomedical Engineering
- Intern Touring Sound Engineer
- Intern Web Developer Internship
- Internship Outdoor Industry Engineering
- Part Time Computational Chemical Engineering
$88K - $116K/yr
Other
Posted 26 days ago
Job description
We are seeking an Upstream Principal CQV Engineer is responsible for overseeing the commissioning and qualification of Upstream systems. This role ensures that all systems are designed, tested, and documented in alignment with project requirements and safety standards.
Upstream Principal CQV Engineer Responsibilities:Upstream System Leadership- Serve as the commissioning and qualification lead for Upstream systems (responsibilities described below).
- Specific experience with chromatography systems, TFF filtration systems, viral filtration systems, and UFDF filtration systems.
- Gain a thorough understanding of system design by reviewing engineering documentation, P&IDs, and design specifications.
- Develop User Requirement Specifications (URS) and Quality Risk Assessment for Equipment and Automated Systems (QRAES).
- Engage with design engineers and SMEs to clarify system intent and operational requirements.
- Ensure alignment with quality, automation, and engineering teams on critical parameters and documentation.
- Create Commissioning Test Plans that translate design intent into testable steps.
- Coordinate with the Automation Team to incorporate all automation functional testing.
- Collaborate with SMEs to ensure system requirements are accurately reflected in test plans.
- Develop Installation, Operational, and Qualification (IOQ) protocols.
- Prepare and submit summary reports documenting commissioning and qualification activities.
- Take custody of the system post-construction and maintain ownership through C&Q completion.
- Perform Lockout/Tagout (LOTO) for system safety.
- Conduct pre-startup safety checks and risk assessments.
- Prepare daily pre-task plans and verify team readiness for safe execution.
- Attend daily commissioning meetings to coordinate activities.
- Execute commissioning and IOQ protocols.
- Resolve issues arising during execution.
- Participate in Factory Acceptance Tests (FATs) and Site Acceptance Tests (SATs) as required.
- Bachelor's degree in Engineering, Life Sciences, Biotechnology, or related technical discipline
- 10+ years of role specific experience
- Experience supporting CQV activities in GMP-regulated pharmaceutical or biotechnology environments
- Hands-on experience with downstream bioprocess equipment and purification systems
- Strong understanding of validation lifecycle documentation (IQ/OQ/PQ, protocols, reports)
- Ability to work independently while collaborating with cross-functional teams
- Strong documentation, organizational, and communication skills
- Experience with digital validation systems such as Kneat
- Experience supporting FAT/SAT, commissioning, and equipment startup
- Familiarity with risk-based validation approaches
- Experience in biologics manufacturing or monoclonal antibody production environments
- Onsite job requirement in Holly Springs, NC
About Verista
Sourced by ZipRecruiter
Industry
Pharmaceutical and medicine manufacturing
Company size
201 - 500 Employees
Headquarters location
Fishers, IN, US
Year founded
2020