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Trial Master File Manager Jobs in Missouri (NOW HIRING)

kindeva

Document Coordinator I

Maryland Heights, MO · On-site

Controlled document management: Create, format, revise, issue, reconcile, archive, and maintain GMP ... SOPs, master batch records, specifications, laboratory methods, protocols, Design History File ...

New

kindeva

Document Coordinator I

Maryland Heights, MO

Controlled document management: Create, format, revise, issue, reconcile, archive, and maintain GMP ... SOPs, master batch records, specifications, laboratory methods, protocols, Design History File ...

New

kindeva

Document Coordinator I

Maryland Heights, MO · On-site

Controlled document management: Create, format, revise, issue, reconcile, archive, and maintain GMP ... SOPs, master batch records, specifications, laboratory methods, protocols, Design History File ...

New

kindeva

Document Coordinator I

Maryland Heights, MO · On-site

Controlled document management: Create, format, revise, issue, reconcile, archive, and maintain GMP ... SOPs, master batch records, specifications, laboratory methods, protocols, Design History File ...

New

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All JobsTrial Master File JobsTrial Master File Manager JobsTrial Master File Manager Jobs in Missouri

Trial Master File Manager information

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$41.7K

$70.9K

$106.9K

How much do trial master file manager jobs pay per year?

As of Aug 21, 2026, the average yearly pay for trial master file manager in Missouri is $70,898.00, according to ZipRecruiter salary data. Most workers in this role earn between $52,100.00 and $87,700.00 per year, depending on experience, location, and employer.

What is a trial master file manager?

A Trial Master File Manager is a professional responsible for overseeing the creation, maintenance, and quality control of the Trial Master File (TMF) in clinical research. The TMF is a collection of essential documents that allow the conduct of a clinical trial to be reconstructed and evaluated. The manager ensures that all documents are complete, accurate, and compliant with regulatory requirements throughout the trial's lifecycle. They work closely with clinical teams, auditors, and regulatory authorities to guarantee readiness for inspections and audits. Their role is crucial for maintaining transparency and credibility in clinical research processes.

What are the key skills and qualifications needed to thrive as a trial master file manager?

To thrive as a Trial Master File Manager, you typically need a strong background in clinical research, regulatory requirements, and document management, often supported by a degree in life sciences or a related field. Familiarity with electronic Trial Master File (eTMF) systems, GCP guidelines, and relevant industry certifications like DIA's TMF Professional Certification is important. Attention to detail, organizational skills, and effective communication help ensure TMF integrity and coordination across cross-functional teams. These skills are crucial for maintaining regulatory compliance, audit readiness, and efficient clinical trial operations.

What are some common challenges faced by trial master file managers, and how can they be addressed?

Trial Master File Managers often encounter challenges such as ensuring TMF completeness, maintaining regulatory compliance, and coordinating document submissions across multiple stakeholders. Keeping documents up-to-date and audit-ready requires strong attention to detail and effective communication with clinical teams, vendors, and sponsors. Leveraging electronic TMF systems, implementing standardized processes, and promoting regular training can help address these challenges and ensure the integrity of the TMF throughout a study.

What are the most commonly searched types of Trial Master File jobs in Missouri?

The most popular types of Trial Master File jobs in Missouri are:

What are popular job titles related to Trial Master File Manager jobs in Missouri?

For Trial Master File Manager jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Trial Master File Manager jobs in Missouri look for?

The top searched job categories for Trial Master File Manager jobs in Missouri are:

What cities in Missouri are hiring for Trial Master File Manager jobs?

Cities in Missouri with the most Trial Master File Manager job openings:

Trial Master File Manager jobs near you
Infographic showing various Trial Master File Manager job openings in Missouri as of June 2026, with employment types broken down into 96% Full Time, and 4% Part Time. Highlights an 77% Physical, 5% Hybrid, and 18% Remote job distribution, with an average salary of $70,898 per year, or $34.1 per hour.

Paralegal - Litigation

UB Greensfelder LLP

Saint Louis, MO • On-site

$80K - $100K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 21 hours ago

Job description

UB Greensfelder is currently seeking a full-time Litigation Paralegal as part of our Business Litigation practice group. Under the direction of attorneys, the Litigation Paralegal will be responsible for assisting in matters resulting from financial services issues, including FINRA, SEC and other state regulatory matters.

UB Greensfelder LLP is an Am Law 200 law firm dedicated to exceeding client expectations and delivering superior, customized legal solutions. The firm's attorneys advise regional, national, and global businesses on a wide range of sophisticated legal matters across more than 25 specialized practice and industry groups. Renowned for its best-in-class client service and litigation excellence, UBG was named "2025 Ohio and Missouri Firm of the Year" by Benchmark Litigation and consistently earns top-tier accolades from Chambers and Partners. Established in 2024 through the merger of Ulmer & Berne LLP and Greensfelder, Hemker & Gale, P.C., UB Greensfelder has quickly emerged as a super-regional powerhouse firm in the Midwest and in top-tier business centers. For more information, please visit www.ubglaw.com. Our Business Begins With You®.

Position responsibilities include: 

  • Serve as the primary and/or lead paralegal on business litigation matters.
  • Assist with fact investigation and evidence development, including document collection, review, analysis, and production.
  • Prepare case summaries, reports, and court or agency filings.
  • Organize and manage deposition, motion, hearing, and trial materials, including exhibits and supporting documents.
  • Coordinate logistics for depositions, hearings, mediations, and trials with attorneys, clients, witnesses, vendors, agencies and courts.
  • Attend meetings, hearings, trials and other proceedings with attorneys, as needed, and utilize trial presentation software.
  • Conduct factual and legal research, including client and witness interviews.
  • Draft correspondence, pleadings, motions, briefs, and other case-related documents.
  • Track deadlines, maintain case calendars, and ensure timely compliance with court rules and applicable regulations.
  • Communicate with clients to gather information and provide case updates while maintaining confidentiality.
  • Create, maintain, and search case databases; manage document organization, chronologies, and production logs.
  • Assist with trial preparation and post-case file management, including records retention and file closure.


Qualified applicants will have:

  • Associate degree or Paralegal Certificate plus three to five years’ litigation experience required. 
  • Experience as a financial services paralegal is strongly preferred.
  • Experience with litigation software solutions, including e-discovery platforms and exhibit and trial organization and presentation software. 
  • Applicable knowledge of motions, discovery, evidence, litigation documentation, agency and court rules and procedures, practices, etc.
  • Strong written and verbal skills and the ability to communicate with all levels of personnel. 
  • Advanced knowledge of Microsoft Office products is a must.

UB Greensfelder provides top-quality, sophisticated legal services, serving business clients ranging from small entrepreneurs to international companies. Our work environment is business casual and we offer a competitive compensation and benefits package, which includes medical/dental/vision, 401(k) with employer contribution, short and long-term disability plans, life insurance, well-being initiatives, and paid parental leave programs.  If you desire to work in a truly people-focused environment for a firm that values its employees, then UB Greensfelder is the firm for you.

UB Greensfelder recognizes the importance of forming inclusive teams of attorneys and staff to foster an environment where creative solutions are made for our clients, and all have the opportunity to thrive and succeed. We encourage candidates from a variety of backgrounds to apply to be a part of our team.