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Trial Master File Associate Jobs in Missouri (NOW HIRING)

Jobgether

$25.75 - $35.25/hr

Our partner is looking for a Associate II, TMF Operations based in Netherlands. This role supports ... You will help ensure Trial Master File (TMF) records are processed, reviewed, maintained, and ...

IQVIA

CRA 2, Oncology, IQVIA

Kansas City, MO

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

CRA 2, Oncology, IQVIA

Kansas City, MO · On-site

$87K - $145K/yr

Ensure copies/originals (as required) site documents are available for filing in the Trial Master File (TMF) and verify that the Investigator's Site File (ISF) is maintained in accordance with GCP ...

IQVIA

CRA 1, IQVIA Biotech

Kansas City, MO

$71K - $145K/yr

Job Overview The Clinical Research Associate I (CRA I) plays a key role in supporting the ... the Trial Master File (TMF) and the Investigator Site File (ISF). A central part of this role ...

IQVIA

CRA 1, IQVIA Biotech

Kansas City, MO · On-site

$71K - $145K/yr

Job Overview The Clinical Research Associate I (CRA I) plays a key role in supporting the ... the Trial Master File (TMF) and the Investigator Site File (ISF). A central part of this role ...

Lunceford Law Firm

Be Seen First

Associate Attorney

Lees Summit, MO · On-site

$90K - $98K/yr

Associate Attorney - Employment Discrimination (Discovery to Trial Preparation) Lunceford Law Firm ... rule letters; filing motions to compel; taking and preparing for depositions; calling and ...

Credgeco

Associate Attorney

Kansas City, MO · Hybrid

Represent clients in court, including motion hearings, pre-trial conferences, and trials. * Engage ... Maintain and update client files, ensuring all case documents are properly organized and accessible.

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Trial Master File Associate information

What is a Trial Master File Associate?

A Trial Master File Associate is a clinical research professional responsible for managing and maintaining the Trial Master File (TMF), which is the collection of essential documents for a clinical trial. Their role ensures that all documentation is complete, accurate, and audit-ready throughout the study. TMF Associates support regulatory compliance by organizing, tracking, and archiving documents, often using electronic systems. They work closely with clinical teams and regulatory authorities to facilitate successful trial conduct and inspections.

What are the key skills and qualifications needed to thrive as a Trial Master File Associate?

To thrive as a Trial Master File (TMF) Associate, you need a solid understanding of clinical research processes, regulatory requirements, and document management, often supported by a degree in life sciences or a related field. Familiarity with electronic TMF (eTMF) systems and knowledge of industry standards like ICH-GCP are typically required. Strong attention to detail, organizational skills, and effective communication help ensure completeness and accuracy in documentation. These skills are crucial for maintaining compliance, supporting clinical trial integrity, and facilitating successful regulatory inspections.

What are some common challenges Trial Master File Associates face when managing clinical trial documentation?

Trial Master File Associates often encounter challenges such as maintaining completeness and accuracy of documentation, ensuring timely filing of essential documents, and staying updated with evolving regulatory requirements. Managing large volumes of documents across multiple studies and coordinating with cross-functional teams can also be demanding. Effective organization, attention to detail, and strong communication skills are essential to overcome these challenges and ensure compliance with Good Clinical Practice (GCP) guidelines.

What is the difference between Trial Master File Associate vs Clinical Trial Coordinator?

AspectTrial Master File AssociateClinical Trial Coordinator
CertificationsMay require GCP or regulatory document management certificationsOften requires GCP training, clinical research certifications
Work EnvironmentFocuses on document management within clinical trialsOversees trial operations, patient coordination, site management
Industry UsageCommonly used in pharmaceutical and biotech companiesUsed across clinical research sites and CROs

The Trial Master File Associate primarily manages and maintains essential trial documentation, ensuring compliance and readiness for audits. In contrast, the Clinical Trial Coordinator oversees the overall conduct of clinical trials, including site management and patient coordination. While both roles require knowledge of GCP and clinical research processes, the Associate focuses on document control, whereas the Coordinator handles broader trial operations.

What are the most commonly searched types of Trial Master File jobs in Missouri?

The most popular types of Trial Master File jobs in Missouri are:

What are popular job titles related to Trial Master File Associate jobs in Missouri?

For Trial Master File Associate jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Trial Master File Associate jobs in Missouri look for?

The top searched job categories for Trial Master File Associate jobs in Missouri are:

What cities in Missouri are hiring for Trial Master File Associate jobs?

Cities in Missouri with the most Trial Master File Associate job openings:

Trial Master File Associate jobs near you
Infographic showing various Trial Master File Associate job openings in Missouri as of August 2026, with employment types broken down into 71% Full Time, and 29% Contract. Highlights an 73% In-person, and 27% Remote job distribution.

Associate II, TMF Operations

Jobgether

On-site

$25.75 - $35.25/hr

Full-time

Posted 11 days ago

Job description

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Associate II, TMF Operations based in Netherlands.

This role supports the accurate and compliant management of essential clinical trial documentation within a global Clinical Research Organization (CRO) environment.
You will help ensure Trial Master File (TMF) records are processed, reviewed, maintained, and archived according to established procedures and regulatory expectations.
The position combines document quality control, records management, and collaboration with international clinical project teams.
You will contribute directly to data integrity and inspection readiness across complex studies and sponsor portfolios.
The role offers exposure to electronic TMF and document management systems while developing your understanding of clinical research operations.
Success requires strong attention to detail, organization, and the ability to manage multiple deadline-driven activities with accuracy.
It is an excellent opportunity for an early-career professional seeking to build expertise in clinical documentation and TMF operations.

Accountabilities
  • Perform TMF Approver and/or TMF QC Reviewer activities in accordance with applicable Standard Operating Procedures (SOPs) and established working practices.
  • Process, review, classify, and resolve rejected Trial Master File documents across complex clinical studies and sponsor portfolios.
  • Manage essential documents in both electronic and hard-copy formats while maintaining accurate records and consistent document standards.
  • Prepare periodic TMF Quality Control checklists and coordinate their review with relevant project team members.
  • Conduct periodic TMF quality control activities to verify compliance with regulatory requirements, ICH GCP principles, sponsor expectations, SOPs, and industry best practices.
  • Work with electronic document management repositories and eTMF systems to review, index, process, and maintain essential clinical trial documentation.
  • Apply standardized document naming conventions and indexing requirements to ensure records are complete, accurate, searchable, and inspection-ready.
  • Collaborate regularly with project teams and colleagues across functions and geographies to resolve documentation issues and support efficient TMF processes.
  • Maintain high standards of accuracy while managing multiple detailed activities within established timelines.
Requirements:
  • University degree preferred, ideally in Life Sciences or a related discipline.
  • Up to 1-2 years of relevant experience in TMF operations, records management, clinical research, CRO, pharmaceutical, or a related environment.
  • General understanding of clinical research principles, clinical trial processes, and the purpose of Trial Master Files.
  • Experience or demonstrated ability in data collection, indexing, document editing, and applying standardized naming conventions.
  • Ability to work effectively with electronic document repositories, eTMF platforms, or similar document management systems, with willingness to develop further technical proficiency.
  • Strong written and verbal communication skills, with the ability to present information clearly, accurately, and concisely.
  • Exceptional attention to detail and accuracy when handling highly structured and sensitive documentation.
  • Strong planning, prioritization, and organizational skills, with the ability to manage multiple tasks in a deadline-driven environment.
  • Proficiency with Microsoft Word and Excel.
  • Strong interpersonal and collaboration skills, with the ability to work effectively in a fast-paced, changing, and globally distributed environment.
  • A proactive, reliable, and quality-focused approach to work, with a commitment to following procedures and maintaining compliance.
Benefits:
  • Opportunity to build specialized experience in TMF operations and clinical research within a global CRO environment.
  • Exposure to international clinical studies, sponsor portfolios, project teams, and industry best practices.
  • Hands-on experience with electronic TMF and document management technologies.
  • Opportunities to collaborate with experienced professionals across clinical research and project teams.
  • A supportive and inclusive working environment that values collaboration, creativity, and professional development.
  • Career development opportunities within a global organization focused on improving clinical research and patient outcomes.
  • An environment committed to equal opportunity, diversity, inclusion, and respectful collaboration.
  • Meaningful work contributing to the quality, compliance, and integrity of clinical trials that can ultimately improve patients' lives.
How Jobgether works:
We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.
We appreciate your interest and wish you the best!
 Why Apply Through Jobgether? 
 
Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.
 
 
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We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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