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Statistical Programming Jobs (NOW HIRING)

Ensure the statistical programming processes and deliverables are aligned with regulatory requirements and internal procedures. Interact with the study statisticians and study team regarding ...

ResponsibilitiesLead and execute statistical programming activities by developing and validating datasets and Tables, Listings, and Figures (TLFs) to ensure high-quality deliverables for pivotal ...

OR · On-site

This is an exciting opportunity to lead Natera's Statistical Programming team, specifically focused on advancing our oncology portfolio through high-impact, practice-changing clinical trials. As a ...

NC · On-site

$116K - $163K/yr

You will lead a study team of statistical programmers to accomplish tasks and communicate issues, as necessary, to line management. This includes communication and quality oversight of the vendor.

You will lead a study team of statistical programmers to accomplish tasks and communicate issues, as necessary, to line management. This includes communication and quality oversight of the vendor.

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Statistical Programming information

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$84.5K

$147.3K

$249K

How much do statistical programming jobs pay per year?

As of Jun 12, 2026, the average yearly pay for statistical programming in the United States is $147,292.00, according to ZipRecruiter salary data. Most workers in this role earn between $125,000.00 and $160,000.00 per year, depending on experience, location, and employer.

What are some common challenges faced by statistical programmers when collaborating with cross-functional teams in clinical research?

Statistical programmers in clinical research often work closely with biostatisticians, data managers, and clinical teams. A common challenge is ensuring clear communication regarding data requirements, analysis specifications, and timelines, as different teams may have varying priorities and technical backgrounds. Navigating frequent changes in study protocols or data standards can also require adaptability and strong project management skills. Building collaborative relationships and maintaining thorough documentation are key to overcoming these challenges and ensuring high-quality, reproducible results.

What is statistical programming?

Statistical programming involves using software tools and programming languages, such as R, SAS, or Python, to manage, analyze, and interpret large sets of data. Professionals in this field write code to perform statistical analyses, create data visualizations, and automate data processing tasks. Statistical programming is widely used in industries like pharmaceuticals, finance, public health, and research to support data-driven decision-making and ensure accurate results.

What are the key skills and qualifications needed to thrive as a Statistical Programmer, and why are they important?

To thrive as a Statistical Programmer, you need strong expertise in statistics, programming languages like SAS or R, and a background in mathematics or computer science. Familiarity with statistical software, clinical data management systems, and regulatory standards such as CDISC is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for collaborating with cross-functional teams. These skills ensure accurate data analysis, regulatory compliance, and successful project delivery in data-driven environments.

What is the difference between Statistical Programming vs Data Analysis?

AspectStatistical ProgrammingData Analysis
Primary FocusDeveloping and implementing statistical models and algorithmsInterpreting data to identify trends and insights
Skills & ToolsProgramming languages (SAS, R, Python), statistical methodsData visualization, descriptive statistics, Excel, SQL
Work EnvironmentPharmaceutical, biotech, or research settingsBusiness, marketing, healthcare sectors
CertificationsOften requires statistical or programming certificationsMay include data analysis or business analytics certifications

While both roles involve working with data, Statistical Programming primarily focuses on creating statistical models and algorithms using programming languages, often in research or clinical settings. Data Analysis emphasizes interpreting data to generate insights for decision-making across various industries. Understanding these differences helps professionals choose the right career path or job focus.

More about Statistical Programming jobs
What cities are hiring for Statistical Programming jobs? Cities with the most Statistical Programming job openings:
What are the most commonly searched types of Statistical Programming jobs? The most popular types of Statistical Programming jobs are:
What states have the most Statistical Programming jobs? States with the most job openings for Statistical Programming jobs include:
Infographic showing various Statistical Programming job openings in the United States as of June 2026, with employment types broken down into 92% Full Time, 4% Part Time, 1% Temporary, and 3% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $147,292 per year, or $70.8 per hour.

Senior Manager, Statistical Programming

Kardigan

South San Francisco, CA

Other

Posted 16 days ago


Job description

Position Title: Senior Manager, Statistical Programming

Department: Clinical Data Sciences & Analytics 

Reports To: Head of Statistical Programming

Location: South San Francisco, CA or Princeton, NJ - On-site 4 days per week (Mon to Thurs) 

Job Overview:

The Senior Manager of Statistical Programming will be responsible for leading Statistical Programming activities. It involves hands-on implementation of statistical analyses using SAS/R, as well as performing quality reviews of deliverables, both for in-house analyses and outsourced programming tasks.

This position serves as a critical bridge between Biostatistics and Clinical Data Management (CDM), ensuring the development of CRFs and the delivery of high-quality clinical data. Additionally, this position will play an important role in helping establish SOPs and programming standards and also build our SCE platform.

ESSENTIAL DUTIES AND RESPONSIBILITIES

Key Project Responsibilities:

  • Provides programming leadership and oversee study to compound-level programming deliverable in collaboration with the Stats lead and cross-functional teams.
  • Serve as the lead programmer to reviews SAP, Data Presentation Plan, Table Shell to align with project objectives and ensures clarity and completeness of programming assumptions and requirements.
  • Lead programming team to produce and/or validate SDTM, ADaM and TLF, for CSR and regulatory requests, publication needs, and ad-hoc analyses.
  • Manage CROs and contractors, ensuring compliance, quality of deliverables, timelines, and budget adherence.
  • Collaborate with biostatisticians and clinical development colleagues to develop/review TLF shells, SDTM, and ADaM specifications.
  • Work closely with Data Management and Biostatistics teams to ensure the accuracy of final databases, analyses, and reports.
  • Develop global tools, such as macros or graphical user interface applications, to enhance the efficiency and capacity of the Statistical Programming team.
  • Develops robust program to create define.xml, Leads the NDA eSubmission package preparation.
  • Assist Biometric in building the statistical computing environment (SCE) platform, including designing folder structure and managing access control.

Initiative Responsibilities:

  • Under guidance from Head of Statistical Programming and Compound PL, implement innovative strategies and technologies to enhance programming processes.
  • Working with manager, establish Statistical Programming standard and deploy programming strategies, specifications and programmed analysis.
  • Proactively plan, implement, and identify issues/risks and provide remediation strategies to improve programming capability.

Qualifications and Preferred Skills

Education:

  • Master's degree in Statistics/Biostatistics, Mathematics, Computer Science, or a related field.

Experience and Skill Set:

  • Minimum of 6 years statistical programming experience in the pharmaceutical, biotech or CRO clinical trial environment.
  • Advanced SAS programming skills. Extensive Hands-on experience with SDTM, ADaM, TLF programming
  • Proficient knowledge in the implementation of CDISC standards (SDTM, ADaM) and regulatory submission requirements.
  • Good knowledge of drug development process, study design, statistical methodology, regulatory guidance, statistical concepts, and medical terminology.
  • Broad expertise in statistical programming and in developing computing strategies.
  • In-depth understanding of CDISC standards including SDTM and ADaM models and extensive experience of their implementation in clinical trials.
  • Demonstrated proficiency in using SAS/R to produce analysis datasets and TFLs.
  • Knowledge of data validation, define.xml generation using Pinnacle 21.
  • Results orientated with proven problem-solving skills and a strong interest in ongoing learning.
  • Excellent communication and collaboration skills, with the ability to work closely with cross-functional teams
  • Experience managing outsourced programming activities and overseeing deliverables from CROs and contractors.
  • Adaptable and thrives in a fast-paced, startup environment while managing multiple priorities effectively.
  • Experience with regulatory audits and inspections and IR (e.g., FDA, PMDA, NMPA, EMA) is a strong advantage.