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Sr Program Manager Jobs in Massachusetts (NOW HIRING)

Landmark Bio

Senior Program Manager

Watertown, MA

$140K - $165K/yr

The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a ...

Landmark Bio

Senior Program Manager

Watertown, MA · On-site

$140K - $165K/yr

The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a ...

Landmark Bio

Senior Program Manager

Watertown, MA

$140K - $165K/yr

The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$145K - $155K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $145,000 - $155,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$140K - $150K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $140,000 -$150,000 annually *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$120K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$120,000-$130,000* *depending on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

$145K - $155K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $145,000 - $155,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Astrion

$140K - $150K/yr

Overview SENIOR PROGRAM MANAGER LOCATION: Hanscom AFB, MA SALARY RANGE : $140,000 -$150,000 annually *depending on experience, certifications, and qualifications JOB STATUS: Full-time;salaried ...

Astrion

$113K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

$115K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$120,000-$130,000* *depending on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

$113K - $145K/yr

Overview Senior Program Manager WORK LOCATION : Hanscom AFB, MA (5 days a week in the office) Salary Range : $130,000 - $145,000 annually* *depending on experience, certifications, and qualifications ...

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$115K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$115K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

$113K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

$113K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$115K - $130K/yr

Overview Senior Program Manager WORK LOCATION :Hanscom AFB, MA Salary Range :$115,000-$130,000* *depen ding on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance:

Astrion

Senior Program Manager

Hanscom Air Force Base, MA · On-site

$130K - $145K/yr

Overview Senior Program Manager WORK LOCATION : Hanscom AFB, MA (5 days a week in the office) Salary Range : $130,000 - $145,000 annually* *depending on experience, certifications, and qualifications ...

Harvard University

Senior Program Manager

Boston, MA

$126K - $126K/yr

The Senior Program Manager is a key administrative and strategic partner to the Principal Investigators in NSAPH focused on environmental and public health applications and state-of-the-art causal ...

Harvard University

Senior Program Manager

Boston, MA · On-site

$57/hr

The Senior Program Manager is a key administrative and strategic partner to the Principal Investigators in NSAPH focused on environmental and public health applications and state-of-the-art causal ...

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Showing results 1-20

All JobsSr Program JobsSr Program Manager JobsSr Program Manager Jobs in Massachusetts

Sr Program Manager information

See Massachusetts salary details

$42.6K

$125.8K

$169.8K

How much do sr program manager jobs pay per year?

As of Jul 30, 2026, the average yearly pay for sr program manager in Massachusetts is $125,762.00, according to ZipRecruiter salary data. Most workers in this role earn between $126,700.00 and $127,200.00 per year, depending on experience, location, and employer.

What is the difference between Sr Program Manager vs Program Manager?

AspectSr Program ManagerProgram Manager
CredentialsTypically requires 5+ years experience, PMP or similar certifications often preferredUsually 3-5 years experience, PMP certification beneficial but not mandatory
Work EnvironmentLeads multiple projects, strategic planning, cross-functional coordinationManages individual projects, focuses on project execution and delivery
Employer & Industry UsageCommon in tech, finance, healthcare, and large corporationsWidely used across industries for project oversight

The main difference between a Sr Program Manager and a Program Manager lies in scope and experience. Sr Program Managers oversee multiple projects and focus on strategic alignment, while Program Managers handle individual projects with a focus on execution. Both roles require strong project management skills, but Sr Program Managers typically have more experience and certifications, reflecting their leadership responsibilities.

How does a Sr Program Manager typically collaborate with cross-functional teams to drive project success?

A Sr Program Manager often acts as a central point of coordination among various cross-functional teams, such as engineering, product, marketing, and operations. They facilitate regular meetings, ensure clear communication of goals and timelines, and proactively identify and resolve potential roadblocks. By leveraging their leadership and organizational skills, Sr Program Managers align diverse teams towards shared objectives and maintain project momentum. This collaborative approach is essential for managing complex programs and delivering results on schedule.

What are the key skills and qualifications needed to thrive as a Sr Program Manager, and why are they important?

To thrive as a Sr Program Manager, you need expertise in project management methodologies, strategic planning, and cross-functional leadership, typically supported by a bachelor’s or master’s degree and several years of relevant experience. Familiarity with tools like Microsoft Project, Jira, and certifications such as PMP or Agile are often required. Exceptional communication, stakeholder management, and problem-solving abilities are standout soft skills in this role. These skills and qualifications are essential for successfully leading complex programs, driving organizational goals, and ensuring effective team collaboration.

Is being a Sr Program Manager stressful?

Being a Sr Program Manager can be stressful due to managing multiple projects, deadlines, and stakeholder expectations. The role often requires strong organizational skills, problem-solving, and the ability to handle high-pressure situations, but it also offers opportunities for leadership and strategic impact.

What job makes $1,000,000 a year?

Senior Program Managers in large technology companies or executive-level roles such as Chief Operating Officers can earn $1,000,000 or more annually, often through base salary, bonuses, and stock options. High compensation typically requires extensive experience, leadership skills, and often involves managing large teams or strategic initiatives.

What jobs pay 500,000 a year in the US?

Senior Program Managers in large corporations or technology firms can earn around $500,000 annually, especially with bonuses and stock options. High-level executive roles such as CEOs, CFOs, and other C-suite positions also often reach or exceed this salary level, typically requiring extensive experience, leadership skills, and advanced certifications. Compensation varies widely based on industry, company size, and geographic location.

What is a Sr Program Manager?

A Senior Program Manager is a professional responsible for overseeing multiple related projects within an organization, ensuring they align with strategic goals. They coordinate teams, manage budgets, and communicate progress to stakeholders, often requiring strong leadership, organizational, and communication skills. This role typically involves strategic planning, risk management, and the use of project management tools like MS Project or Jira.
What are the most commonly searched types of Sr Program jobs in Massachusetts? The most popular types of Sr Program jobs in Massachusetts are:
What cities in Massachusetts are hiring for Sr Program Manager jobs? Cities in Massachusetts with the most Sr Program Manager job openings:
Sr Program Manager jobs near you
Infographic showing various Sr Program Manager job openings in Massachusetts as of July 2026, with employment types broken down into 83% Full Time, 15% Part Time, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $125,762 per year, or $60.5 per hour.

Senior Program Manager

Landmark Bio

Watertown, MA

$140K - $165K/yr

Full-time

Re-posted 11 days ago

Job description

We are seeking a self-driven, team-oriented, and entrepreneurial-minded Senior Program Manager to join Landmark Bio. The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a functional understanding of the technical aspects of cell and gene therapy programs and awareness of Landmark Bio's business objectives.

The Senior Program Manager will support cross-functional program execution by driving operational coordination, maintaining program management tools and documentation, and serving as a key liaison between internal teams and external clients. This role is responsible for managing timelines, dashboards, communications, and process improvements while ensuring programs are executed efficiently and effectively.

Responsibilities
  • Support the planning, coordination, and execution of internal and client-facing programs
  • Develop and maintain program timelines, schedules, dashboards, and risk registers with support from senior program managers
  • Coordinate program materials and shared resources, escalating constraints and risks as appropriate
  • Generate and maintain documentation for program scope changes and client communications
  • Assist with capturing and sharing lessons learned across programs to improve operational efficiency
  • Create and update presentations for team meetings, leadership reviews, and client discussions
  • Serve as a Smartsheet super user for the organization, creating, managing, and optimizing complex workflows, automations, dashboards, and reporting tools
  • Develop and maintain program management resources including trackers, templates, dashboards, presentation materials, and other operational tools
  • Evaluate and recommend process improvements to enhance team collaboration, visibility, and efficiency
  • Collaborate cross-functionally on new system evaluations, tool implementations, and training initiatives
  • Maintain internal Microsoft Teams sites and external SharePoint client sites to ensure documentation is organized, current, and accessible
  • Archive program documentation at the close of programs in accordance with internal procedures
  • Own and maintain program management documentation including:
    • Program charters
    • Program plans and schedules
    • RACI matrices
    • Risk registers
    • Business requirements
    • Policies and procedures
    • Training materials
  • Ensure all documentation is accurate, complete, version-controlled, and properly stored
  • Serve as the primary point of contact for assigned clients
  • Coordinate and manage client meetings, teleconferences, and onsite visits
  • Prepare agendas, meeting minutes, action items, and follow-up communications
  • Build collaborative relationships with internal stakeholders and external partners to support successful program delivery
  • Assist in training personnel on evolving program management tools and systems
  • Develop training materials including slide decks, guides, and reference documentation
Qualifications
  • BS degree with 7+ years relevant experience (GMP pharmaceutical, biologics, and/or cell and gene therapy field) is required
  • PMP certification desired
  • High degree of proficiency in Smartsheet is required, including advanced skills in workflow design and implementation, template creation and management, user training and support, and reporting and analytics
  • Strong communication, problem solving, planning, and project management skills
  • Ability to support more than one project of a reasonable size simultaneously
$140,000 - $165,000 a year
Landmark Bio is dedicated to translating cutting-edge research into life-changing therapies. The company provides CMC development and GMP manufacturing capabilities for cell and gene therapies and other novel modalities, and partners with academic, biotech, and industry collaborators to advance next-generation manufacturing technologies.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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