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Sr Process Engineer Jobs in Rochester, MN (NOW HIRING)

Sr VDC Engineer

Rochester, MN

$109K - $142K/yr

Gilbane is seeking a Senior VDC Engineer to lead constructability and coordination tasks on a project by using technology and processes. This role will sit in the office and on job sites as ...

Senior IT Cloud Engineer

Rochester, MN · On-site

$56.75 - $75.75/hr

The IT Senior Cloud Engineer ensures that enterprise cloud solutions are optimized for cost and ... Creates and determines Cloud systems specifications, input/output processes and working parameters ...

New

Quality Engineer I

Rochester, MN · On-site

$73K - $94K/yr

Monitors manufacturing process, fabrication, inspection, test and shipping activities. Recommends ... senior engineers. • Ensures that records/files are initiated and maintained in all relevant ...

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Showing results 1-20

Sr Process Engineer information

See Rochester, MN salary details

$76.2K

$123.1K

$173.3K

How much do sr process engineer jobs pay per year?

As of Jul 11, 2026, the average yearly pay for sr process engineer in Rochester, MN is $123,114.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,700.00 and $136,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Sr Process Engineer, and why are they important?

To thrive as a Sr Process Engineer, you need a solid background in chemical, mechanical, or industrial engineering, often with a bachelor's or master's degree and relevant industry experience. Familiarity with process simulation software (such as Aspen Plus or HYSYS), Six Sigma or Lean certifications, and knowledge of safety and regulatory standards are typically required. Strong problem-solving, project management, and communication skills help distinguish top performers in this role. These skills and qualifications are vital for optimizing processes, ensuring efficiency and safety, and driving continuous improvement in complex manufacturing environments.

What are Sr Process Engineers?

Senior Process Engineers are experienced professionals responsible for designing, optimizing, and overseeing the processes used in manufacturing or production environments. They analyze workflows, troubleshoot process issues, and implement improvements to increase efficiency, reduce costs, and ensure product quality. Sr Process Engineers often lead teams, manage projects, and work closely with other departments such as quality assurance, maintenance, and operations. Their expertise is crucial in industries like chemicals, pharmaceuticals, oil and gas, and food processing. They typically hold a degree in engineering and have several years of experience in process engineering roles.

How does a Sr Process Engineer typically collaborate with cross-functional teams to improve manufacturing efficiency?

Sr Process Engineers work closely with teams such as production, quality assurance, maintenance, and R&D to identify areas for process optimization. They often lead or participate in cross-functional meetings to gather data, analyze workflow bottlenecks, and implement solutions that enhance efficiency and product quality. Effective communication and project management skills are essential, as Sr Process Engineers must balance technical requirements with practical constraints while ensuring all stakeholders are aligned with proposed changes.

What is the difference between Sr Process Engineer vs Process Engineer?

AspectSr Process EngineerProcess Engineer
QualificationsBachelor's degree in engineering, 5+ years experience, certifications like Six SigmaBachelor's degree in engineering or related field, 1-3 years experience
ResponsibilitiesLead process improvements, optimize manufacturing processes, mentor junior staffAssist in process development, data collection, support process optimization
Work EnvironmentManufacturing plants, industrial facilities, cross-functional teamsManufacturing settings, engineering teams, project-based tasks

The main difference between a Sr Process Engineer and a Process Engineer lies in experience, responsibility level, and scope of work. The Sr Process Engineer typically leads projects, mentors others, and has more advanced qualifications, while the Process Engineer supports and executes process improvements under supervision.

What are popular job titles related to Sr Process Engineer jobs in Rochester, MN? For Sr Process Engineer jobs in Rochester, MN, the most frequently searched job titles are:
What cities near Rochester, MN are hiring for Sr Process Engineer jobs? Cities near Rochester, MN with the most Sr Process Engineer job openings:
Infographic showing various Sr Process Engineer job openings in Rochester, MN as of July 2026, with employment types broken down into 2% Locum Tenens, 90% Full Time, 5% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $123,114 per year, or $59.2 per hour.
Senior Engineer - Center of Regenerative Biotherapeutics

Senior Engineer - Center of Regenerative Biotherapeutics

Mayo Clinic

Rochester, MN • On-site

$148K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 4 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 688 frontline employees who took The Breakroom Quiz

105th of 881 rated healthcare providers


Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

For the Center of Regenerative Biotherapeutics, the Senior Engineer designs and develops components of biomedical-related engineering systems, applying knowledge of complex principles, theories, concepts, tools and techniques to the design challenges -- Essentially we engineer solutions to manufacturing problems in cutting edge science but also problem solve a plethora of issues. Our Senior Engineer: 

  • Serves as a Technical Lead for projects
  • Provides technical and work direction to project team members and completes technical work as needed
  • Mentors and coaches other staff as required
  • May lead in evaluating new technologies and capital equipment
  • Understands and complies with relevant portions of Quality Management System
  • Has unit-specific expertise in safety risk management and continues to work to develop expertise in regulatory requirements applicable to his/her unit

Necessary skills: Self-starter who functions effectively in a multi-disciplinary development environment. Demonstrated ability to effectively communicate with team members, physicians and health care providers. Possesses effective oral communication and presentation skills. Develops engineering and technical documentation.


Qualifications

BS in Engineering or a related field (Biomedical Engineering preferred) and 5 years of professional engineering experience; Or MS in Engineering or related field and 3 year of professional engineering experience; Or, PhD in Engineering or related field and 1 year of professional engineering experience. 

Masters or PhD preferred, as well as early-to-mid career level candidates. 


Exemption Status
Exempt
Compensation Detail
99,070.40 - $148,616.00 / year; Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Mostly standard business hours. Some after work or before work may be needed. On-call rotation required.
Weekend Schedule
Rarely weekends however some circumstances may call for limited weekend hours.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'.  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter
Stephanie BairdQualifications:

BS in Engineering or a related field (Biomedical Engineering preferred) and 5 years of professional engineering experience; Or MS in Engineering or related field and 3 year of professional engineering experience; Or, PhD in Engineering or related field and 1 year of professional engineering experience. 

Masters or PhD preferred, as well as early-to-mid career level candidates. 


What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Mayo Clinic logo

About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919