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Sr Clinical Data Manager Jobs (NOW HIRING)

Clinical Data Manager

San Diego, CA · On-site

$110K - $120K/yr

Exact title (Clinical Data Manager I, Clinical Data Manager II, or Senior Clinical Data Manager) will depend on experience and skill level. Essential Duties and Responsibilities The main ...

Clinical Data Manager

Durham, NC · On-site

$68K - $171K/yr

Responsible for providing data review training and guidance to Sr. Clinical Data Coordinators that ... Minimum of 5 years of data management experience is required. * Bachelor's degree OR certification ...

New

Clinical Data Manager The Clinical Data Manager performs activities pertaining to the conduct of ... Responsible for providing data review training and guidance to Sr. Clinical Data Coordinators that ...

New

Clinical Ink is seeking a Clinical Data Manager to join our Data Management team based remotely across the United States! This individual will design, implement and manage all data management ...

New

The Clinical Data Manager (CDM) handles project management documentation, clinical data management activities, and system implementations for EDETEK's eClinical, and may be assigned work on other ...

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Sr Clinical Data Manager information

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$123.1K

$184.5K

How much do sr clinical data manager jobs pay per year?

As of Aug 16, 2026, the average yearly pay for sr clinical data manager in the United States is $123,055.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $137,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Sr Clinical Data Manager?

To thrive as a Sr Clinical Data Manager, you need expertise in clinical data management, knowledge of regulatory requirements (such as GCP and FDA), and typically a degree in life sciences or related fields. Proficiency with data management systems like Medidata Rave, Oracle Clinical, and experience with CDISC standards or relevant certifications are commonly required. Strong project management, leadership, and communication skills help you effectively oversee teams and ensure data quality. These skills and qualifications are crucial for ensuring accurate, compliant, and timely clinical trial data that supports successful regulatory submissions.

What does a Sr Clinical Data Manager do?

A Sr Clinical Data Manager oversees the collection, management, and quality control of clinical trial data. Their responsibilities include designing data collection systems, ensuring data accuracy and integrity, managing databases, and coordinating with clinical research teams. They play a critical role in ensuring that clinical data meets regulatory standards and is ready for analysis and submission. Typically, Sr Clinical Data Managers also mentor junior staff and help develop data management protocols and best practices.

What are some typical challenges a Sr Clinical Data Manager might face when overseeing multiple clinical trials simultaneously?

A Sr Clinical Data Manager often manages several trials at once, which can lead to challenges such as coordinating data collection across diverse study sites, ensuring consistent data quality, and meeting tight regulatory deadlines. Balancing these demands requires strong organizational skills, proactive communication with cross-functional teams, and effective delegation of tasks to junior data managers. Staying updated on evolving data standards and regulatory requirements is also crucial to avoid delays or compliance issues.
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Infographic showing various Sr Clinical Data Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 6% Part Time, and 6% Contract. Highlights an 72% In-person, and 28% Remote job distribution, with an average salary of $123,055 per year, or $59.2 per hour.

Senior Clinical Data Manager

Supernus Pharmaceuticals, Inc.

Rockville, MD • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 17 days ago


Job description

Supernus Pharmaceuticals is an award-winning biopharmaceutical company with more than 30 years of experience in developing and commercializing products that treat central nervous system (CNS) diseases. At Supernus, we develop innovative products that help treat neurological and psychiatric conditions. At Supernus, we develop innovative products that help treat neurological and psychiatric conditions. We currently have 8 products in the market that are making a real impact on patient outcomes.
Job Summary:
To provide leadership, strategic direction, and oversight for end-to-end clinical data management activities throughout the lifecycle of clinical trials - from study start-up through trial execution and study closeout - ensuring quality, compliant, and timely clinical data delivery.
Essential Duties & Responsibilities:
  • Lead all data management (DM) activities for one or more clinical trials.
  • Contribute to developing study protocols, statistical analysis plans, and clinical study reports.
  • Collaborate with Database Development on study database, eCRF, and edit checks design.
  • Manage user acceptance testing (UAT) of study database with cross-functional team members (including Clinical Operations, Clinical Development, Drug Safety, and Biostatistics).
  • Manage cross-functional collaboration with internal team members (from Clinical Operations, Clinical Development, Drug Safety, and Biostatistics) and external vendors (for trial conduct).
  • Develop and enforce study timeline for all DM and/or DM-related milestones.
  • Develop and enforce all DM-related plans, agreements, and guidelines (e.g., data management plan [DMP], data quality plan [DQC], data transfer agreement [DTA], and electronic CRF completion guidelines [eCCG]).
  • Collaborate with Document Management team to archive DM-related documents in Trial Master File (TMF).
  • Write DM-related SOPs and/or Job aids and contribute to improving DM processes.

Non-Essential Duties & Responsibilities:
  • Attends and participates in internal and external training sessions.

Supervisory Responsibilities:
  • May supervise Clinical Data Associates as needed.
  • Provides leadership or management in an effective manner consistent with Company Values towards defined Corporate Objectives.
  • Understands Company Policy and procedure to be able to guide direct reports appropriately, if applicable.

Knowledge & Other Qualifications:
  • Master's degree with at least 6 years or Bachelor's degree with at least 8 years of in pharmaceutical, CRO, Biotech, or health related field or industry.
  • Strong experience in data captures systems and clinical data review.
  • Strong knowledge of industry standards such as GCP, GCDMP, and CDISC (CDASH and SDTM).
  • Working knowledge of medical terminology and coding (MedDRA/WHO-Drug).
  • Working knowledge of data privacy rules in relation to clinical data management.
  • Nursing/medical/biology background is a plus.
  • Strong project and risk management skills with great attention to detail.
  • Excellent interpersonal and communication skills in English language (writing, speaking, and comprehending).
  • Computer literate with proficiency of Microsoft Office package including Word, Outlook, and Excel.

Other Characteristics:
  • Ability to work independently and as part of a team.
  • Ability to maintain high ethical standards of integrity and quality.
  • Capable of performing other duties as assigned by management.
  • Capable of being innovative and dynamic in approach to work.
  • Authorized to legally work in the United States without visa sponsorship.

Physical Requirements / Work Environment:
  • Sedentary work. Exerting up to 10 pounds of force occasionally and/or carrying objects. Sedentary work involves sitting most of the time.
  • The worker is required to have close visual acuity to perform an activity such as: preparing and analyzing data and figures; transcribing; viewing a computer screen, iPad, or other electronic device; and extensive reading.
  • The worker is not substantially exposed to adverse environmental conditions.

Compensation:
At Supernus, we offer a competitive compensation package that reflects your experiences and contributions. The expected salary range for fully qualified candidates applying for this role is $145,000 to $160,000. This range is what the Company reasonably expects to offer for the position and is not reflective of the full compensation scale of the role. This range may be modified in the future. An individual's salary within the range is based on multiple factors, which may include and are not limited to education, relevant experience, knowledge, length of industry experience and organizational needs.
You also will be able to participate in a competitive benefits package, including but not limited to: health, dental, vision, paid time off, 401k company match, company paid life insurance and health and wellness benefits. The total compensation package for this position also includes other compensation elements such as stock equity awards, employee stock purchase programs and participation in our Company's discretionary annual bonus program.
Supernus Pharmaceuticals is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, national origin, disability, protected veteran status, age or any other characteristic protected by law.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.