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Senior Validation Engineer Jobs in California (NOW HIRING)

3B Staffing LLC

Senior Validation Engineer

Alameda, CA · On-site

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities: * Review/approve ...

New

3B Staffing LLC

Senior Validation Engineer

Alameda, CA · On-site

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities: * Review/approve ...

New

Syner-G

Sr. Validation Engineer

San Diego, CA · On-site

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Syner-G

Sr. Validation Engineer

San Diego, CA

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Syner-G

Sr. Validation Engineer

San Diego, CA · On-site

The Sr. Validation Engineer will serve as a subject matter expert, support complex technical projects, and provide guidance to junior team members. KEY RESPONSIBILITIES (This list is not exhaustive ...

Microsoft

Senior Validation Engineer

Mountain View, CA · On-site

$119K - $234K/yr

We are looking for a Senior Validation Engineer with expertise in one or more of the following validation domains : functional, electrical, high speed interfaces, memory, power/performance, debug/BU ...

New

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

Lonza

Senior Validation Engineer - CSV (OT)

Vacaville, CA · On-site

$93K - $155K/yr

Paid Time Off The Senior Validation Engineer - CSV at Lonza will be responsible for leading and executing validation activities for manufacturing processes, equipment, computerized systems, and ...

Lonza

Senior Validation Engineer - CSV (OT)

Vacaville, CA · On-site

$93K - $155K/yr

Paid Time Off The Senior Validation Engineer - CSV at Lonza will be responsible for leading and executing validation activities for manufacturing processes, equipment, computerized systems, and ...

Everpure

MTS - Senior Validation Engineer

Santa Clara, CA · On-site

$180K - $270K/yr

THE ROLE As a Validation Engineer (IC) on the Drive Qualification team, you will design and execute PCIe-focused validation and debug for Everpure SSDs. You'll own link and protocol test coverage ...

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

Alphatec Spine

Validation Engineer II

Carlsbad, CA · On-site

Seeks guidance from and collaborates with senior validation engineers; may informally assist with onboarding or knowledge sharing for newer team members. * Maintains regular and consistent attendance ...

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Senior Validation Engineer information

See California salary details

$34

$63

$97

How much do senior validation engineer jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for senior validation engineer in California is $63.92, according to ZipRecruiter salary data. Most workers in this role earn between $51.01 and $72.60 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior validation engineer, and why are they important?

To thrive as a Senior Validation Engineer, you need a solid background in engineering, quality assurance, and regulatory compliance, typically supported by a relevant degree and experience in validation within regulated industries. Familiarity with validation protocols (IQ, OQ, PQ), statistical analysis tools, and systems like FDA 21 CFR Part 11 is crucial. Strong problem-solving, attention to detail, and effective communication skills help ensure successful project outcomes and cross-functional collaboration. These skills and qualifications are essential to maintain product quality, meet regulatory standards, and drive continuous improvement.

What does a senior validation engineer do?

A Senior Validation Engineer is responsible for ensuring that products, systems, or processes meet regulatory standards and function as intended. They develop and execute validation protocols, analyze test data, and document results to confirm compliance with industry and company standards. Senior Validation Engineers often lead validation projects, collaborate with cross-functional teams, and mentor junior staff. Their work is critical in industries like pharmaceuticals, biotechnology, and manufacturing, where product safety and efficacy are essential.

What are some typical challenges faced by senior validation engineers when leading validation projects?

Senior Validation Engineers often encounter challenges such as managing tight project timelines, ensuring compliance with evolving regulatory standards, and coordinating cross-functional teams. Balancing the needs of production, quality assurance, and regulatory affairs requires strong communication and project management skills. Additionally, troubleshooting unexpected validation failures and documenting results thoroughly are key aspects that demand both technical expertise and attention to detail.

What is the difference between Senior Validation Engineer vs Validation Specialist?

AspectSenior Validation EngineerValidation Specialist
CredentialsBachelor's or Master's in Engineering, Life Sciences, or related fields; often with certifications like GxP or CSVSimilar educational background; certifications like GxP or CSV are common
Work EnvironmentDesigns and oversees validation protocols in manufacturing, biotech, or pharmaceutical settingsExecutes validation tasks, tests, and documentation in similar environments
Employer & IndustryPharmaceutical, biotech, medical device companiesSame industries, often working under validation teams
Search & ComparisonOften compared for experience level and responsibilitiesCommonly searched together for validation roles

The main difference is that a Senior Validation Engineer typically leads validation projects, designs protocols, and oversees validation activities, while a Validation Specialist focuses on executing validation tests and documentation. Both roles require similar credentials and work in comparable environments, but the Senior Validation Engineer has more responsibility for planning and oversight.

What are the most commonly searched types of Validation Engineer jobs in California?

The most popular types of Validation Engineer jobs in California are:

What are popular job titles related to Senior Validation Engineer jobs in California?

For Senior Validation Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Senior Validation Engineer jobs in California look for?

The top searched job categories for Senior Validation Engineer jobs in California are:

What cities in California are hiring for Senior Validation Engineer jobs?

Cities in California with the most Senior Validation Engineer job openings:

What are popular job titles related to Senior Validation Engineer jobs in CA?

For Senior Validation Engineer jobs in CA, the most frequently searched job titles are:

Senior Validation Engineer jobs near you
Infographic showing various Senior Validation Engineer job openings in California as of August 2026, with employment types broken down into 88% Full Time, 5% Part Time, 2% Temporary, and 5% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $132,962 per year, or $63.9 per hour.

Senior Validation Engineer

3B Staffing LLC

Alameda, CA • On-site

Full-time

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

Senior Validation Engineer Overview: Seeking an experienced SQA professional to ensure compliance and quality of SDLC deliverables for regulated IT applications. Responsibilities:
  • Review/approve SDLC deliverables: MVP testing, FMEA, IQ, OQ, PQ, trace matrices, system releases.
  • Provide validation expertise for IT applications and ensure compliance readiness.
  • Collaborate with development teams to align deliverables with business and compliance standards.
  • Oversee CAPAs, change controls, and defect management.
Qualifications:
  • 7+ years in software validation and QA.
  • Proficient in GxP regulations, validation principles, and automated testing.
  • Experience with Salesforce, Veeva, and tools like JIRA, Tosca, ALM, and Confluence.
  • Knowledge of Agile and Waterfall methodologies.

Apply