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Senior Statistical Programmer Jobs in Missouri (NOW HIRING)

Jobgether

This is a senior statistical leadership opportunity supporting clinical development programs in ... You will work closely with clinical, programming, regulatory, and sponsor teams to ensure robust ...

Ra

Marketing Analytics Manager

Saint Louis, MO

Mid - Senior Level This is what you will do.. You will be using quantitative methods to assess the ... Who is proficient in Applied Statistics/Econometrics, Statistical Programming, Database Marketing ...

Ra

Marketing Analytics Manager

Buffalo, MO

Mid - Senior Level This is what you will do.. You will be using quantitative methods to assess the ... Who is proficient in Applied Statistics/Econometrics, Statistical Programming, Database Marketing ...

Leonardo DRS

Senior Quality Engineer

West Plains, MO · On-site

$95 - $125/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Location: West Plains, MO 65775 Job ID:114905 Senior Quality Engineer Job Responsibilities ... Develop and generate statistical reports on inspection activities and results, new product or ...

Jobtailor

Decision Scientist Lead

California, MO · On-site

$140 - $240/hr

... statistics, engineering, or other quantitative field) * Proven experience working directly with senior executive leadership * Expert communicator in written and verbal form * Proven experience ...

New

MasterCard

Senior AI Engineer

O Fallon, MO · Hybrid

$97K - $134K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Title and Summary Senior AI Engineer Mastercard's Business & Market Insights (B&MI) group empowers ... Apply traditional ML and statistical modeling (regression, clustering, forecasting, ensemble ...

Socket.dev

Senior Algorithm Engineer

California, MO · On-site

$186 - $317/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... and senior product technology process engineers. The Film and Scatterometry Technology (FaST ... Apply computational imaging, computer vision, signal processing, and statistical analysis ...

watlow

Sr. Financial Analyst

Saint Louis, MO · On-site

$81K - $101K/yr

Senior Financial Analyst (FP&A - Business Partnering & Strategic Projects) St. Louis, Missouri ... Bachelor's degree in Finance, Accounting, Economics, Statistics, Engineering or a related field ...

Mastercard, Inc.

Senior AI Engineer

O Fallon, MO · On-site

$97K - $134K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Title and Summary Senior AI Engineer Mastercard's Business & Market Insights (B&MI) group empowers ... statistical modeling (regression, clustering, forecasting, ensemble methods) in hybrid ...

Walmart

(USA) Senior, Data Scientist

Noel, MO · On-site

$90K - $180K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

You will be a great fit if: - You architect end-to-end ML/AI systems -- from feature engineering ... Solid understanding of statistics, experimental design, and causal/measurement thinking.

Walmart

(USA) Senior, Data Scientist

Anderson, MO · On-site

$90K - $180K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

You will be a great fit if: - You architect end-to-end ML/AI systems -- from feature engineering ... Solid understanding of statistics, experimental design, and causal/measurement thinking.

Walmart

(USA) Senior, Data Scientist

Noel, MO · On-site

$90K - $180K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

You will be a great fit if: - You architect end-to-end ML/AI systems -- from feature engineering ... Solid understanding of statistics, experimental design, and causal/measurement thinking.

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All JobsStatistical Programmer JobsSenior Statistical Programmer JobsSenior Statistical Programmer Jobs in Missouri

Senior Statistical Programmer information

See Missouri salary details

$77.4K

$120.3K

$157.1K

How much do senior statistical programmer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for senior statistical programmer in Missouri is $120,340.00, according to ZipRecruiter salary data. Most workers in this role earn between $100,400.00 and $138,800.00 per year, depending on experience, location, and employer.

What is a senior statistical programmer?

A Senior Statistical Programmer is responsible for developing, testing, and validating statistical programs used for clinical trial data analysis. They work primarily with statistical software like SAS to generate tables, listings, and figures (TLFs) for regulatory submissions and research studies. This role requires strong programming skills, knowledge of statistical methodologies, and an understanding of clinical trial processes. Senior Statistical Programmers also collaborate with statisticians, data managers, and regulatory teams to ensure data integrity and compliance with industry standards.

What are the typical responsibilities and team dynamics for a senior statistical programmer?

As a Senior Statistical Programmer, you will typically be responsible for designing, developing, and validating statistical programs for clinical trial data analysis and reporting. You’ll work closely with biostatisticians, data managers, and clinical project teams to ensure data quality and regulatory compliance, often contributing to the creation of submission datasets and study reports. The role usually involves both independent work and active collaboration, with seasoned programmers frequently mentoring junior staff and participating in process improvement initiatives. This team-oriented structure offers exposure to a variety of projects and stakeholders, making it a dynamic environment ideal for those who enjoy both analytical tasks and cross-functional teamwork.

What are the key skills and qualifications needed to thrive as a senior statistical programmer, and why are they important?

To thrive as a Senior Statistical Programmer, a strong background in statistical analysis, programming (often in SAS and R), and a relevant degree such as in statistics, mathematics, or computer science is essential. Experience with regulatory submission standards (like CDISC SDTM/ADaM), clinical trial software, and certifications such as SAS Certified Advanced Programmer are highly valued. Outstanding attention to detail, problem-solving abilities, and effective communication skills help individuals excel in this collaborative and deadline-driven role. These skills are crucial for ensuring accurate data analysis, regulatory compliance, and successful teamwork in high-stakes research environments.

What are the most commonly searched types of Statistical Programmer jobs in Missouri?

The most popular types of Statistical Programmer jobs in Missouri are:

What are popular job titles related to Senior Statistical Programmer jobs in Missouri?

For Senior Statistical Programmer jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Senior Statistical Programmer jobs in Missouri look for?

The top searched job categories for Senior Statistical Programmer jobs in Missouri are:

What cities in Missouri are hiring for Senior Statistical Programmer jobs?

Cities in Missouri with the most Senior Statistical Programmer job openings:

What are popular job titles related to Senior Statistical Programmer jobs in MO?

For Senior Statistical Programmer jobs in MO, the most frequently searched job titles are:

Senior Statistical Programmer jobs near you
Infographic showing various Senior Statistical Programmer job openings in Missouri as of August 2026, with employment types broken down into 57% Full Time, and 43% Contract. Highlights an 100% In-person job distribution, with an average salary of $120,340 per year, or $57.9 per hour.

Principal Statistician - Ophthalmology

Jobgether

Remote

Full-time

Posted 9 days ago

Job description

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Principal Statistician - Ophthalmology based in Netherlands.

This is a senior statistical leadership opportunity supporting clinical development programs in ophthalmology within a fully remote European environment. You will provide statistical expertise across the full clinical trial lifecycle, from protocol development through clinical study reporting and regulatory activities. The role combines hands-on statistical work with project leadership, mentoring, quality oversight, and cross-functional collaboration. You will work closely with clinical, programming, regulatory, and sponsor teams to ensure robust study design and high-quality analyses. You will also contribute to complex projects, integrated analyses, submissions, and potentially regulatory agency interactions. With significant responsibility and autonomy, you will help translate complex statistical concepts into clear insights that support critical healthcare decisions.

Accountabilities
  • Serve as a senior statistical resource across clinical development projects, providing expertise throughout the study lifecycle from protocol development through the Clinical Study Report (CSR).
  • Lead or oversee statistical activities for assigned projects, ensuring high-quality deliverables are completed within agreed timelines and according to applicable standards.
  • Develop, review, and oversee Statistical Analysis Plans (SAPs), including well-structured mock-ups for tables, listings, and figures, and collaborate with sponsors as required.
  • Act as Lead Biostatistician when assigned, supporting statistical aspects of protocols, randomization schedules, analyses, and clinical study reports.
  • Provide statistical input into database design, annotated case report forms, analysis datasets, tables, listings, figures, and related programming specifications.
  • Conduct independent review and quality control of statistical deliverables, ensuring analyses are consistent with approved SAPs, specifications, protocols, and expected results.
  • Direct and mentor other biostatistics professionals, contribute to training programs, and support the development of statistical capabilities across the department.
  • Lead complex or multiple projects, including submissions and integrated analyses, and support regulatory agency meetings or responses to statistical questions when needed.
  • Monitor project milestones, workload, timelines, and resource requirements, proactively communicating risks, scope changes, or delivery challenges to management.
  • Represent biostatistics on cross-functional project teams, contributing to internal meetings, strategic discussions, and project decision-making.
  • Participate in Data Safety Monitoring Board (DSMB) and Data Monitoring Committee (DMC) activities, including charter development and independent statistical oversight, with the potential to serve as a voting statistician.
  • Support statistical programming activities as required, including R-based analyses and related statistical deliverables.
  • Ensure project documentation, quality-control records, and statistical programs remain complete, organized, current, and inspection-ready.
  • Contribute to business development activities, including proposals, budgets, and sponsor bid defense meetings.
  • Apply relevant SOPs, work instructions, ICH guidelines, and other applicable regulatory requirements throughout project execution.
Requirements
  • Graduate degree in biostatistics, statistics, or a closely related quantitative discipline.
  • Extensive experience in clinical trials or an equivalent combination of education and professional experience, with a demonstrated ability to lead multiple projects or programs of studies.
  • Strong proficiency in R programming and practical experience applying statistical programming techniques in clinical research.
  • Extensive knowledge of statistical study design, analysis methodologies, clinical research practices, and relevant regulatory requirements.
  • End-to-end experience supporting clinical trials across the lifecycle, from protocol development and study design through analysis and CSR preparation.
  • Experience preparing or reviewing Statistical Analysis Plans, statistical specifications, analysis datasets, tables, listings, figures, and related clinical documentation.
  • Experience with regulatory submissions and interactions with regulatory agencies is highly desirable.
  • Strong leadership and mentoring capabilities, with the ability to guide biostatisticians and contribute to training and professional development.
  • Excellent written and verbal communication skills, with the ability to explain complex statistical concepts clearly to technical and non-technical stakeholders.
  • Strong organizational and prioritization skills, with the ability to manage multiple projects, shifting priorities, deadlines, and competing demands.
  • Collaborative and proactive approach, with the confidence to contribute ideas, challenge assumptions constructively, and work effectively across multidisciplinary and international teams.
  • Fluent in English, with strong reading, writing, speaking, and comprehension skills.
Benefits
  • Fully remote working opportunity within Europe.
  • Flexible environment designed to support collaboration across distributed international teams.
  • Competitive compensation and comprehensive total rewards.
  • Opportunities for career development and professional progression.
  • Supportive and engaged line management.
  • Access to technical and therapeutic-area training.
  • Peer recognition and employee reward programs.
  • Opportunity to work on complex clinical development programs with a meaningful impact on healthcare and patient outcomes.
  • Exposure to multidisciplinary teams, global sponsors, and a broad range of clinical research projects.
  • Opportunities to contribute to innovative statistical approaches, regulatory submissions, and high-impact clinical programs.
  • An inclusive and collaborative working culture that encourages employees to bring their authentic selves to work.
How Jobgether works:
We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team.
We appreciate your interest and wish you the best!
 Why Apply Through Jobgether? 
 
Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.
 
 
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