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Senior Process Engineer Jobs in Upton, MA (NOW HIRING)

DPS Group

Process Engineer

Framingham, MA · On-site

The Process Engineer will contribute to the creation of design and technical documents to support our DPS client scope and objectives. Common work products will include generation of PFDs, P&IDs ...

FIBA Technologies, Inc.

Process Engineer

Littleton, MA · On-site

Process Engineer - Manufacturing Automation Position Summary The Process Engineer - Manufacturing Automation is responsible for developing, maintaining, troubleshooting, and improving automated ...

FIBA Technologies, Inc.

Process Engineer

Littleton, MA · On-site

Process Engineer - Manufacturing Automation Position Summary The Process Engineer - Manufacturing Automation is responsible for developing, maintaining, troubleshooting, and improving automated ...

FIBA Technologies, Inc.

Process Engineer

Littleton, MA · On-site

$90 - $120/hr

Process Engineer - Manufacturing Automation Position Summary The Process Engineer - Manufacturing Automation is responsible for developing, maintaining, troubleshooting, and improving automated ...

WhiteCap Search

Process Engineer

Framingham, MA · On-site

Our client is seeking an experienced Process Engineer to support a biopharmaceutical manufacturing facility. This individual will provide engineering support across manufacturing equipment, facility ...

Winchester Interconnect

Process Engineer

CT · On-site

$90K - $120K/yr

Process Engineer Job ID: # 360 Location: Dayville, CT Department: Engineering Reports To: Engineering Manager Job Type: Full-Time Compensation: $90,000 - $120,000 Summary: At Aptiv, we inspire the ...

Syner-G

Process Engineer

Plainville, MA

We are seeking an experienced Process Engineer to lead and support the successful transfer of manufacturing processes and technologies between development, clinical, and commercial manufacturing ...

Curaleaf

Process Engineer

Webster, MA · On-site

Process Engineer Location: Webster, MA The candidate must be able to travel 75% + of the time throughout the nation and will be working out of the Webster, MA location when not traveling. About the ...

Syner-G

Process Engineer

Plainville, MA · On-site

We are seeking an experienced Process Engineer to lead and support the successful transfer of manufacturing processes and technologies between development, clinical, and commercial manufacturing ...

Syner-G

Process Engineer

Plainville, MA

We are seeking an experienced Process Engineer to lead and support the successful transfer of manufacturing processes and technologies between development, clinical, and commercial manufacturing ...

Curaleaf

Process Engineer

Boston, MA

$90K - $110K/yr

Process Engineer Location: Webster, MA The candidate must be able to travel 75% + of the time throughout the nation and will be working out of the Webster, MA location when not traveling. About the ...

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Showing results 21-40

All JobsProcess Engineer JobsSenior Process Engineer JobsSenior Process Engineer Jobs in Upton, MA

Senior Process Engineer information

See Upton, MA salary details

$81.5K

$131.7K

$185.4K

How much do senior process engineer jobs pay per year?

As of Sep 6, 2026, the average yearly pay for senior process engineer in Upton, MA is $131,679.00, according to ZipRecruiter salary data. Most workers in this role earn between $113,100.00 and $146,200.00 per year, depending on experience, location, and employer.

What does a senior process engineer do?

A Senior Process Engineer is responsible for designing, optimizing, and overseeing processes within manufacturing or production environments. They analyze workflows, troubleshoot issues, and implement improvements to increase efficiency, safety, and product quality. Senior Process Engineers often lead projects, mentor junior engineers, and collaborate with cross-functional teams to ensure operational excellence. Their expertise is vital in industries like chemicals, pharmaceuticals, oil and gas, and food processing.

What are the key skills and qualifications needed to thrive as a senior process engineer?

To thrive as a Senior Process Engineer, you need a strong background in chemical or process engineering, problem-solving skills, and typically a bachelor's or master's degree in a relevant field. Expertise in process simulation software (such as Aspen Plus or HYSYS), Six Sigma or Lean certifications, and familiarity with process control systems are highly valued. Outstanding analytical abilities, leadership, and effective communication set top performers apart in this role. These skills and qualifications are crucial for optimizing processes, ensuring safety and compliance, and leading teams to achieve operational excellence.

What are some common challenges senior process engineers face when working on cross-functional teams?

Senior Process Engineers often collaborate with professionals from various departments, such as operations, quality, and maintenance. A common challenge is aligning diverse priorities and communication styles to achieve shared project goals. Successfully managing these differences requires strong interpersonal and project management skills, as well as the ability to translate technical concepts for non-engineering colleagues. Regular meetings and clear documentation can help ensure everyone stays informed and engaged throughout the process.

What is the difference between Senior Process Engineer vs Process Engineer?

AspectSenior Process EngineerProcess Engineer
QualificationsBachelor's or Master's in Engineering, often with 5+ years experienceBachelor's degree in Engineering or related field, typically 1-3 years experience
ResponsibilitiesLeading process improvements, mentoring, project managementSupporting process development, data analysis, assisting senior staff
Work EnvironmentDesign teams, manufacturing plants, R&D departmentsManufacturing facilities, engineering teams, operational support

Senior Process Engineers typically have more experience, leadership duties, and oversee complex projects, while Process Engineers focus on supporting process development and implementation. Both roles are essential in manufacturing and engineering industries, but the senior role involves greater responsibility and strategic planning.

How much does a senior process engineer earn?

A senior process engineer typically earns between $80,000 and $130,000 annually, depending on experience, industry, and location. They often have specialized skills in process optimization, project management, and may hold certifications like Six Sigma or PE licensure.

What are the most commonly searched types of Process Engineer jobs in Upton, MA?

The most popular types of Process Engineer jobs in Upton, MA are:

What cities near Upton, MA are hiring for Senior Process Engineer jobs?

Cities near Upton, MA with the most Senior Process Engineer job openings:

Senior Process Engineer jobs near you
Infographic showing various Senior Process Engineer job openings in Upton, MA as of August 2026, with employment types broken down into 1% As Needed, 73% Full Time, 22% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $131,679 per year, or $63.3 per hour.

Sr. Process Development Engineer - OSD

Alkermes

Waltham, MA • On-site

$140K - $154K/yr

Full-time

Re-posted 8 days ago

Job description


Join the Alkermes Process Development team as Senior Engineer, where you will provide technical leadership and support the development of innovative small molecule pharmaceutical dosage forms. You will operate within cross functional teams to ensure alignment during drug product development, join the CMC teams, and provide leadership for development teams. You will design and execute experimental studies to develop well understood, robust oral solid dosage manufacturing processes. Key duties are process design, equipment set-up, troubleshooting equipment, running experiments, collecting/evaluating data to identify and implement process/equipment improvements reducing waste and increasing process reliability. This position requires experience in oral solid dosage processing techniques used for manufacture of dosage forms (such as milling, blending, wet and dry granulation, compression, encapsulation and coating). You will also lead process development activities and clinical manufacturing in a GMP facility for oral solid dosage forms, maintaining GMP standards.
Responsibilities
  • Act as a subject matter expert in oral solid dosage processing, quickly adopt new technologies, and provide technical guidance, training, and direction to teams.
  • Lead lab-scale process development and ensure effective knowledge transfer to pilot-scale manufacturing through reports, presentations, and technical collaboration.
  • Design and execute experiments to deepen process knowledge, optimize performance, and improve product robustness.
  • Support the operation of a GMP clinical manufacturing facility, enabling diverse processing capabilities and supporting early-stage development activities.
  • Oversee batch manufacturing activities, ensuring adherence to safety, quality, and documentation standards while producing GMP batches at multiple scales.
  • Responsible for the creation of batch records, change controls and standard operating procedures for area of responsibility with a strong focus on efficiency and continuous improvement.
  • Author CMC sections for IND, NDA, and other regulatory filings.
  • Develop process trains and flows, ensuring scientifically driven, scalable, and reproducible processes with well-defined critical parameters.
  • Maintaining compliance with all aspects of cGMP, safety and environmental legislation and company policies.
  • Present technical data to stakeholders, communicate risks and solutions, and collaborate with formulators, engineers, safety, and quality teams.
  • Mentor and train junior staff.

Qualifications
  • Ph.D. and 3+ years in engineering/scientific discipline; M.S. and 10+ years of related experience; B.S. and 15+ years of related experience in pharmaceutical solid oral dosage processing
  • Subject matter proficiency across a range of processing techniques such as, powder blending, encapsulation, granulation, compression, and coating.
  • Demonstrated ability to work successfully in a fast-paced team/matrix environment as well as independently manage priorities and maintain timelines for multiple activities.
  • Demonstrated collaborative leadership, strong people skills, and excellent verbal and written communication skills.
  • Demonstrated experience in small molecule process development, scale up and technical transfer.

Preferred Requirements:
  • Knowledge of design of experiments, data analysis and data interpretation for process development studies.
  • Solid understanding of the drug development lifecycle and the critical role of process development, including its impact on product quality, scalability, and timelines.
  • Demonstrated expertise in mechanical and chemical engineering principles applied to general process systems and equipment, including specialized knowledge of oral solid dosage (OSD) drug manufacturing systems and associated equipment.
  • "Hands-on" ability to install and troubleshoot instrumentation and equipment. Strong knowledge of process safety and risk assessments.
  • Technical problem-solving ability utilizing current research and technologies.
  • Understanding of ICH, FDA, and USP guidelines and the ability to apply these guidelines in context of the stage of drug development.
  • Previous experience with Process Analytical Technology and drug product formulation is preferred.
  • Minimal travel required (10-15%) to visit manufacturing facilities.

The annual base salary for this position ranges from $140,000 to $154,000. In addition, this position is eligible for an annual performance pay bonus. Exact compensation may vary based on skills, training, knowledge, and experience. Alkermes offers a competitive benefits package. Additional details can be found on our careers website: www.alkermes.com/careers#working-here
#LI-MB1
About Us
Why join Team Alkermes?
Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.

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