ZipRecruiter

Log In

1

Senior Principal Engineer Jobs in Oregon (NOW HIRING)

Nike

Senior Principal Software Engineer

Beaverton, OR · On-site

$130K - $180K/yr

Sr. Principal Engineer CONSUMER PRODUCT AND INNOVATION , PHK-BEAVERTON WHO YOU WILL WORK WITH You will report to the Sr. Director, Reporting & Intelligence Engineering and be part of the Engineering ...

Waymark

Senior/Principal Data Engineer

OR · On-site +1

$125K - $172K/yr

This is a senior to principal-level individual contributor role who combines deep backend engineering fundamentals with specialized expertise in Electronic Health Record (EHR) data integration. You ...

CSC Generation

Principal Engineer

OR · On-site +1

Reports to: Sr. Director of IT Location: Cottonwood Heights, Utah (Hybrid - 3x/week in-office) or ... As Principal Engineer, Application Development , you will lead a team of developers building the ...

next page

Showing results 1-20

All JobsPrincipal Engineer JobsSenior Principal Engineer JobsSenior Principal Engineer Jobs in Oregon

Senior Principal Engineer information

See Oregon salary details

$86.7K

$164.3K

$226.8K

How much do senior principal engineer jobs pay per year?

As of Aug 16, 2026, the average yearly pay for senior principal engineer in Oregon is $164,334.00, according to ZipRecruiter salary data. Most workers in this role earn between $132,700.00 and $182,900.00 per year, depending on experience, location, and employer.

What is a senior principal engineer?

A Senior Principal Engineer is a highly experienced technical leader who is responsible for guiding the overall engineering direction and strategy within an organization. They typically possess deep expertise in their field, provide mentorship to other engineers, and influence major architectural and technical decisions. Senior Principal Engineers often collaborate with cross-functional teams, ensure best practices are followed, and play a critical role in driving innovation. Their work has a significant impact on the company's products and technical vision.

What are the key skills and qualifications needed to thrive as a senior principal engineer?

To excel as a Senior Principal Engineer, you need deep technical expertise in your engineering discipline, advanced problem-solving abilities, and typically a bachelor's or master's degree in engineering or a related field. Proficiency with industry-standard design and simulation software, project management tools, and relevant certifications (such as PMP or PE) are often required. Exceptional leadership, strategic thinking, and strong communication skills distinguish top performers in this role. These competencies are vital for leading complex projects, driving innovation, and effectively guiding engineering teams to achieve organizational goals.

What does a senior principal engineer do?

Senior Principal Engineers often serve as technical leaders on cross-functional projects, collaborating closely with product managers, architects, and development teams to define technical direction and ensure architectural consistency. They provide deep expertise to solve complex engineering challenges, mentor other engineers, and help align project goals with the organization's strategic vision. Their role frequently involves facilitating communication between different departments and ensuring technical decisions support both immediate project needs and long-term scalability.

What is the difference between Senior Principal Engineer vs Lead Engineer?

AspectSenior Principal EngineerLead Engineer
CredentialsTypically requires a bachelor's or master's degree in engineering, with extensive industry experienceSimilar educational background, often with additional certifications or specialized training
Work EnvironmentFocuses on high-level technical strategy, innovation, and mentorship across projectsLeads specific projects or teams, overseeing technical execution and coordination
Industry UsageCommon in large corporations and R&D settingsFound in both startups and established companies, often in project-based roles

While both roles require strong technical expertise, the Senior Principal Engineer typically focuses on strategic technical leadership and innovation at an organizational level, whereas the Lead Engineer manages project execution and team coordination. The Senior Principal Engineer often operates at a higher, more strategic level within the engineering hierarchy.

What are the most commonly searched types of Principal Engineer jobs in Oregon?

The most popular types of Principal Engineer jobs in Oregon are:

What are popular job titles related to Senior Principal Engineer jobs in Oregon?

For Senior Principal Engineer jobs in Oregon, the most frequently searched job titles are:

What job categories do people searching Senior Principal Engineer jobs in Oregon look for?

The top searched job categories for Senior Principal Engineer jobs in Oregon are:

What cities in Oregon are hiring for Senior Principal Engineer jobs?

Cities in Oregon with the most Senior Principal Engineer job openings:

What are popular job titles related to Senior Principal Engineer jobs in OR?

For Senior Principal Engineer jobs in OR, the most frequently searched job titles are:

Senior Principal Engineer jobs near you
Infographic showing various Senior Principal Engineer job openings in Oregon as of August 2026, with employment types broken down into 87% Full Time, 6% Part Time, 6% Contract, and 1% Nights. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $164,334 per year, or $79 per hour.

Principal/Senior Principal Process Engineer, Aseptic Operations/Filling

F. Hoffmann-La Roche AG

Hillsboro, OR • On-site

$114.38 - $256.75/hr

Other

Posted 11 days ago

Job description

Overview

Genentech's Hillsboro Technical Operations (HTO) in Hillsboro, Oregon focuses on drug product manufacturing across Component Prep & Compounding, Liquid/Lyophilized Filling, Automated/Manual Inspection, Packaging/Finished Products, and Distribution. The site is expanding and seeks a Principal or Senior Principal Process Engineer to lead product technology transfers, optimize processes, and deploy new technologies while maintaining the highest quality standards.

Key Responsibilities
  • Lead and support product technology transfers to the HTO site.
  • Collaborate with cross‑functional teams, including Manufacturing, Quality Assurance, and Engineering Science & Technology, to ensure regulatory compliance.
  • Provide guidance to Process Engineering – Filling group engineers on operations.
  • Plan and execute technology transfers and process validation activities; manage projects, develop protocols, conduct execution, and produce reports.
  • Support equipment qualification and commissioning for new manufacturing equipment and processes.
  • Prepare and present rationale for tech transfer activities during periodic audits and regulatory inspections.
  • Author, review, and approve relevant sections of regulatory submissions.
  • Represent the site on cross‑functional and multi‑site teams for tech transfers and new technologies.
  • Lead and facilitate Gap Assessments, Risk Assessments, and other deliverables for tech transfers and NME launches.
  • Mentor and train junior level engineers.
  • Maintain expertise in aseptic processing and stay abreast of technical and industry advancements.
Qualifications
  • Bachelor’s or Master’s degree in Engineering, Pharmaceutical Sciences, or a related field.
  • Minimum 8 years of relevant experience for Principal Engineer, 12 years for Senior Principal Engineer.
  • Experience in the pharma/biotech industry.
  • Strong knowledge of pharmaceutical/biologics processing principles, cGMP regulations, and regulatory requirements (FDA, EMA).
  • In‑depth knowledge of formulation, component preparation, and/or filling process development and characterization.
  • Proficiency in data analysis and statistical tools for process monitoring and optimization.
  • Excellent problem‑solving, troubleshooting, and root cause analysis skills.
  • Professional communication and collaboration skills with a cross‑functional team orientation.
  • Detail‑oriented with a commitment to compliance and high‑quality results.
Compensation and Benefits

Salary ranges for Hillsboro, OR: $114,380 – $212,420 for Principal level and $138,000 – $256,750 for Senior Principal level. Actual pay is based on experience, level, qualifications, geographic location, and other factors permitted by law. A discretionary annual bonus may be available. Relocation benefits are also provided.

Equal Opportunity Employer

Genentech is an equal opportunity employer. We employ, promote, and otherwise treat all employees and applicants on the basis of merit, qualifications, and competence. Our policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of protected veteran status, disability status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please complete the Accommodations for Applicants form.

#J-18808-Ljbffr

Apply