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Senior Computer Engineer Jobs in Ohio (NOW HIRING)

University of Dayton

Senior Alt-PNT Research Engineer

Dayton, OH · On-site

$101.60K - $139.50K/yr

Senior Alt-PNT Research Engineer Job No: 503563 Work Type: Staff Full Time (1500 hours or greater ... Minimum Qualifications: - Master's degree in Electrical Engineering, Computer Engineering, Computer ...

KBR, Inc.

Senior Reverse Engineer

Beavercreek, OH · On-site

$142K - $195K/yr

Senior Reverse Engineer Why Join Us? * Innovative Projects: KBR's work is at the forefront of ... Master's degree in Computer Engineering, Electrical Engineering, or a related field * Security ...

Waypoint Human Capital

Senior Software Engineer

Dayton, OH · On-site

$119.10K - $157K/yr

Senior Software Engineer Position Type: Full-time Location: Dayton, OH (Primary); Huntsville, AL ... Bachelor's degree in Computer Science, Computer Engineering, or related field * Minimum 5+ years of ...

Peerless Technologies

Senior Software Engineer

Dayton, OH

$115.70K - $152.60K/yr

Peerless is searching for an experienced Senior Software Engineer to design, develop, and maintain ... Bachelor's degree or higher in Computer Science, Computer Engineering, or related field * Minimum 5 ...

Waypoint Human Capital

Senior Software Engineer

Dayton, OH · On-site

$119.10K - $157K/yr

Senior Software Engineer Position Type: Full-time Location: Dayton, OH (Primary); Huntsville, AL ... Bachelor's degree in Computer Science, Computer Engineering, or related field * Minimum 5+ years of ...

Waypoint Human Capital

Senior Software Engineer

Dayton, OH

$119.10K - $157K/yr

Senior Software Engineer Position Type: Full-time Location: Dayton, OH (Primary); Huntsville, AL ... Bachelor's degree in Computer Science, Computer Engineering, or related field * Minimum 5+ years of ...

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Senior Computer Engineer information

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$56.6K

$120.3K

$174.5K

How much do senior computer engineer jobs pay per year?

As of May 29, 2026, the average yearly pay for senior computer engineer in Ohio is $120,317.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,300.00 and $136,400.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Computer Engineer, and why are they important?

To thrive as a Senior Computer Engineer, you need advanced knowledge of computer architecture, hardware and software integration, and a relevant degree in computer engineering or a related field. Familiarity with design tools like CAD software, programming languages (such as C/C++ or Python), and industry certifications (like Cisco or CompTIA) is highly beneficial. Leadership, problem-solving, and effective communication are crucial soft skills for managing projects and mentoring junior engineers. These competencies ensure the successful development, troubleshooting, and optimization of complex computing systems, driving innovation and efficiency in technology solutions.

What are some typical challenges faced by Senior Computer Engineers when leading project teams?

Senior Computer Engineers often encounter challenges such as balancing technical leadership with hands-on development work, managing cross-functional team communication, and ensuring that projects stay on schedule. They are responsible for translating high-level requirements into actionable tasks while mentoring junior engineers and resolving technical roadblocks. Effective time management and strong collaboration skills are key, as they frequently coordinate between engineering, product management, and other stakeholders to deliver complex systems on time.

What are Senior Computer Engineers?

Senior Computer Engineers are experienced professionals who design, develop, and maintain computer hardware and software systems. They often lead engineering teams, oversee complex projects, and ensure that systems meet organizational requirements for performance and security. Their work may include developing new technologies, optimizing existing systems, and mentoring junior engineers. Senior Computer Engineers typically have several years of experience and a strong background in computer science or engineering.

Is it possible to make 300K as a software engineer?

Senior computer engineers and experienced software engineers in high-demand industries or specialized fields can earn salaries of $300,000 or more, especially with advanced skills, certifications, and leadership roles. Achieving this level often requires extensive experience, working in high-paying sectors like finance or tech, and sometimes includes bonuses or stock options.
What are the most commonly searched types of Computer Engineer jobs in Ohio? The most popular types of Computer Engineer jobs in Ohio are:
What cities in Ohio are hiring for Senior Computer Engineer jobs? Cities in Ohio with the most Senior Computer Engineer job openings:
Senior Computer Engineer jobs near you
Infographic showing various Senior Computer Engineer job openings in Ohio as of May 2026, with employment types broken down into 74% Full Time, 24% Part Time, and 2% Contract. Highlights an 84% Physical, 8% Hybrid, and 8% Remote job distribution, with an average salary of $120,317 per year, or $57.8 per hour.
Sr. Engineer, Computer System Validation

Sr. Engineer, Computer System Validation

Axogen

Vandalia, OH • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 10 days ago

Job description

Axogen is committed to building and maintaining a strong and gratifying company culture that fosters professional growth. Our hands-on and personal approach makes transitioning to a new job a seamless and enjoyable process. Most benefits are effective on day one!
Axogen is an equal opportunity employer and does not discriminate against applicants on the basis of race, color, creed, religion, ancestry, age, sex, marital status, national origin, disability or veteran status.
Why you'll love working at Axogen:
  • Friendly, open, and fun team culture that values unique perspectives
  • Company-wide dedication to profoundly impacting patients' lives
  • Comprehensive, high-quality benefits package effective on date of hire
  • Educational assistance available for all employees
  • Matching 401(k) retirement plan
  • Paid holidays, including floating holidays, to be used at your discretion
  • Employee Stock Purchase Plan
  • Referral incentive program

Axogen Mission and Business Purpose
Our business purpose is to restore health and improve quality of life by making restoration of peripheral nerve function an expected standard of care. We aim to lead the markets we serve by always requiring the solutions we offer patients and caregivers provide an improved benefit-to-risk profile as compared to existing standards of care. To ensure we deliver improved benefit-to-risk solutions, we will guide and expect the market and design requirement specifications underlying our engineering, business development, and clinical research activities, objectively target advancements in standards of care.
Job Summary of the Sr. Engineer, Computer System Validation
The Sr. Engineer, Computer System Validation, will demonstrate strong expertise in Computer System Validation (CSV), data integrity, and periodic review of systems. This role will support validation and compliance efforts for computerized systems with GxP impact and coordinate between business units and IT, as needed. This position reports to the Supervisor, Quality Systems and will partner closely with IT, QA, and various business units (e.g., R&D, Clinical, Operations, and Finance). Occasional travel to other Axogen sites may be required.
Requirements of the Sr. Engineer, Computer System Validation
  • Bachelor's Degree in Biomedical Engineering, Information Technology, Pharmaceutical Sciences, or related field, along with 5 years of experience in the Software Industry, specializing in GxP and validated systems.
  • In-depth knowledge of GAMP 5 and 21 CFR Part 11 principles.
  • Strong track record in authoring, executing, and approving validation documentation across the full software development lifecycle (SDLC).
  • Strong understanding of QMS systems and document routing/tracking in a compliance-driven environment.
  • Experience managing change controls and periodic review processes.
  • Strong verbal and written communication skills - able to engage technical and non-technical audiences.
  • Familiarity with ERP, LIMS, MES, ELN, and SaaS-based GxP systems.
  • Formal training or certification in Computer System Validation (CSV), such as courses offered by ISPE, NSF, CfPIE, or equivalent recognized organizations preferred.
  • Knowledge of MasterControl or other E-QMS platforms.

Responsibilities of the Sr. Engineer, Computer System Validation
The specific duties of the Sr. Engineer, Computer System Validation include but are not limited to:
  • Develop, execute and review risk-based validation strategies aligned with GAMP 5, 21 CFR Part 11, EU Annex 11, and data integrity standards.
  • Co-author, review, and/or approve validation deliverables: URS, FRS, Risk Assessments, IQ/OQ/PQ Protocols, Summary Reports, Traceability Matrices, and Data Integrity Checklists.
  • Support validation efforts for new and upgraded GxP systems, including but not limited to SaaS, ERP, EBR, LIMS, MES, and QMS platforms.
  • Manage periodic review of computerized systems by collaborating with Business and System owners to execute the reviews, identify any gaps and plan corrective actions.
  • Maintain and improve the CSV program in alignment with regulatory guidance and regulations.
  • Support internal and external audits related to computerized systems and data integrity compliance.
  • Elicit, document, and manage business and user requirements through workshops, interviews, and process mapping.
  • Translate requirements into functional specifications, traceability matrices, and change controls.
  • Serve as a trusted liaison between business stakeholders, QA, technical teams, and external vendors to drive project milestones while ensuring seamless communication and compliance.
  • Route and track validation documents and project deliverables in the QMS for review and approval.
  • Create, manage and/or review change controls in the QMS for system updates or improvements and proactively drive them forward through the full approval lifecycle.
  • Ensure that document updates, system revisions, and process changes are appropriately documented and maintained according to regulatory expectations.
  • Ensure vendor deliverables meet Axogen's internal quality and regulatory standards.
  • Identify process gaps, propose improvements, and advocate for continuous enhancement of validation and compliance practices.

Location (any of these)
APC - 913 Industrial Drive Place, Vandalia, OH 45377
Tampa HQ - 111 West Oak Avenue, Tampa, FL 33602
Alachua HQ - 13631 Progress Boulevard #400, Alachua, FL 32615
Benefits/Compensation
This position is eligible for an annual bonus.
Benefits offered for this position include Health, Dental, Vision, Matching 401K, Paid Time Off, 9 Paid Holidays + 3 Floating Holidays, Dependent Care Flexible Spending Accounts, Medical Flexible Spending Accounts, Tuition Reimbursement, Paid Parental Leave, Paid Caregiver Leave, Basic Life Insurance, Supplemental Life Insurance, Employee Stock Purchase Plan, and Disability Insurance, as described in more detail in summary plan descriptions.
Salary Range
$92,293-$115,367 USD
Axogen follows healthcare system guidelines with respect to credentialing, vaccinations and other employment/compliance related requirements, as well as CDC guidance. Axogen reserves the right to amend its policies from time to time in its sole discretion.

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