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Senior Clinical Trial Associate Jobs (NOW HIRING)

Ardelyx

Clinical Trial Associate

Newark, CA · On-site

$86K - $105K/yr

The Clinical Trial Associate (CTA) supports the Clinical Trial Management team in the execution of ... and other senior team members with day-to-day study activities to ensure study milestones and ...

Spyglass Pharma

Clinical Trial Associate

Aliso Viejo, CA · On-site

$35.50 - $48.50/hr

We are seeking a Clinical Trial Associate (CTA) / Senior CTA to join our team at SpyGlass Pharma. The CTA is responsible for executing the tasks on the clinical team throughout the clinical trial.

Ardelyx

Clinical Trial Associate

Newark, CA · On-site

$86K - $105K/yr

The Clinical Trial Associate (CTA) supports the Clinical Trial Management team in the execution of ... and other senior team members with day-to-day study activities to ensure study milestones and ...

Spyglass Pharma

Clinical Trial Associate

Aliso Viejo, CA · On-site

$35.50 - $48.50/hr

We are seeking a Clinical Trial Associate (CTA) / Senior CTA to join our team at SpyGlass Pharma. The CTA is responsible for executing the tasks on the clinical team throughout the clinical trial.

Spyglass Pharma

Clinical Trial Associate

Aliso Viejo, CA · On-site

$90K - $110K/yr

We are seeking a Clinical Trial Associate (CTA) / Senior CTA to join our team at SpyGlass Pharma. The CTA is responsible for executing the tasks on the clinical team throughout the clinical trial.

Cellectis

Clinical Trial Associate

Manhattan, NY · On-site

$36.75 - $50.25/hr

The Clinical Trial Associate (CTA) supports clinical study teams in the execution and oversight of clinical trials under the direction of the Vice President, Development Operations, with day-to-day ...

Cellectis

Clinical Trial Associate

Manhattan, NY · On-site

$36.75 - $50.25/hr

The Clinical Trial Associate (CTA) supports clinical study teams in the execution and oversight of clinical trials under the direction of the Vice President, Development Operations, with day-to-day ...

Spyglass Pharma

Clinical Trial Associate

Aliso Viejo, CA · On-site

$35.50 - $48.50/hr

We are seeking a Clinical Trial Associate (CTA) / Senior CTA to join our team at SpyGlass Pharma. The CTA is responsible for executing the tasks on the clinical team throughout the clinical trial.

Ardelyx

Clinical Trial Associate

Newark, CA

$86K - $105K/yr

The Clinical Trial Associate (CTA) supports the Clinical Trial Management team in the execution of ... and other senior team members with day-to-day study activities to ensure study milestones and ...

Kura Oncology

Clinical Trial Associate

Boston, MA

$36.50 - $49.75/hr

Job Summary: The Clinical Trial Associate (CTA) supports the operational execution of clinical ... Receives clear instruction, guidance and direction from more senior level roles or even solves ...

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How much do senior clinical trial associate jobs pay per hour?

As of Aug 10, 2026, the average hourly pay for senior clinical trial associate in the United States is $39.99, according to ZipRecruiter salary data. Most workers in this role earn between $32.21 and $43.99 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior clinical trial associate?

To thrive as a Senior Clinical Trial Associate, you need a solid understanding of clinical research processes, regulatory guidelines (such as GCP and ICH), and typically a bachelor's degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and relevant certifications like SOCRA or ACRP are commonly required. Attention to detail, strong organizational skills, and effective communication set high performers apart in this position. These skills ensure the accurate, compliant, and efficient execution of clinical trials, supporting successful study outcomes and regulatory submissions.

What is the difference between Senior Clinical Trial Associate vs Clinical Trial Associate?

AspectSenior Clinical Trial AssociateClinical Trial Associate
Required CredentialsBachelor's degree, experience in clinical trials, often some certificationBachelor's degree, entry-level experience, may have certification
Work EnvironmentLeads trial activities, mentors junior staff, manages complex tasksSupports trial activities, follows protocols, assists senior staff
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsPharmaceutical companies, CROs, biotech firms
Common Search & ComparisonMore experienced, leadership responsibilitiesEntry-level, support role

The main difference between a Senior Clinical Trial Associate and a Clinical Trial Associate lies in experience, responsibilities, and leadership. Senior associates typically lead trial activities and mentor others, while clinical trial associates support trial operations under supervision. Both roles are essential in clinical research and are commonly found in pharmaceutical and biotech industries.

What are some common challenges faced by senior clinical trial associates, and how can they be effectively managed?

Senior Clinical Trial Associates often encounter challenges such as managing multiple studies simultaneously, ensuring compliance with evolving regulatory requirements, and maintaining clear communication across cross-functional teams. Effectively managing these challenges involves strong organizational skills, up-to-date knowledge of regulatory guidelines like GCP and ICH, and proactive collaboration with project managers, data managers, and site coordinators. Utilizing project management tools and regularly scheduled team meetings can also help streamline workflows and address issues promptly.
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Senior Clinical Trial Associate jobs near you
Infographic showing various Senior Clinical Trial Associate job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 72% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $83,169 per year, or $40 per hour.

Clinical Trial Associate/Senior Clinical Trial Associate

Crescent Biopharma

Waltham, MA

$108K - $132K/yr

Full-time

Posted 12 days ago

Job description

Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies as single agents and as part of combination regimens to treat a range of solid tumors. For more information, visit www.crescentbiopharma.com and follow the Company on LinkedIn and X.

We are seeking a CTA/Senior CTA who will work with the Clinical Study Lead and Director of Clinical Operations to support the conduct of clinical trials. You will partner with the Clinical Study Lead to ensure studies are completed on time, within budget, and in compliance with SOPs, FDA regulations and ICH/GCP guidelines.

You may independently manage components of clinical studies, including but not limited to vendor oversight, budgets, responsibility for a subset of sites or countries, or phases of the trial (startup period, for example), with oversight. 

Responsibilities
  • Support the Clinical Study Lead and Clinical Operations team in the day-to-day operational activities of clinical trials to ensure study objectives, timelines, quality standards, and regulatory requirements are met.
  • Support oversight of CROs, vendors, and investigator sites, including review of monitoring visit reports, site communications, and follow-up on study-related actions and issues.
  • Maintain study tracking tools for key study documentation (e.g., Form FDA 1572) and operational activities, including site activation, enrollment, monitoring visit status, IRB/EC approvals, safety letter distribution, training compliance, and study milestones.
  • Support Trial Master File (eTMF) activities, including document collection, filing, reconciliation, quality control reviews, and inspection readiness efforts.
  • Support preparation of study agendas, meeting minutes, action item logs, and study status reports while ensuring effective communication across internal teams, CROs, vendors, and investigator sites.
  • Collaborate cross-functionally with Regulatory Affairs, Clinical Supplies, Data Management, Safety, Quality, and other functional areas to support study deliverables and timelines.
  • Manage study team training records and ensure compliance with applicable SOPs, regulations, study requirements, and company policies.
  • Manage system access requests for study team and site personnel, as needed.
  • Communicate and escalate study risks, protocol deviations, operational challenges, and other study-related issues as appropriate.
Education & Experience
  • Bachelor’s degree in scientific or related field with 2+ years of experience in Clinical Operations, clinical research or healthcare, or equivalent experience
  • Knowledge of FDA regulatory requirements and ICH/GCP guidelines essential
  • Demonstrated efficiency in partnering with CROs and vendors
  • Computer proficiency (Word, Excel, PowerPoint, Project)
  • Works proactively and efficiently in a fast-paced, high change environment
  • Must have excellent interpersonal, written and verbal communication skills
  • Ability to interact well with various team members and provide value added support to project
  • Outstanding organization skills
  • Strong analytical, strategic thinking, and problem-solving skills.
  • Ability to quickly learn new tools, systems, and processes to improve efficiency
What We Offer
  • Opportunity to join a mission-driven team where you'll contribute to impactful work, take on varied responsibilities, and grow quickly in a dynamic environment
  • Competitive compensation, including base salary, performance bonus, and equity
  • 100% employer-paid benefits package
  • Flexible PTO
  • Two, one-week company-wide shutdowns each year
  • A commitment to your professional development, with access to resources, mentorship, and growth opportunities
Salary Range
The anticipated salary range for this position is $108,000 to $132,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography. 
 
Additional Description for Pay Transparency:
The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography. Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation – Unlimited PTO; Sick time – 10 days per calendar year; Holiday pay, including two Company shut downs; Parental Leave – 16 weeks within one year of the birth/adoption/foster care of a child; FMLA; Military Leave. Additional information can be found - https://www.crescentbiopharma.com/careers/#benefits

Please note:

Crescent Biopharma is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status. 

Please note, Crescent does not accept unsolicited resumes from external agencies or recruiters. Submission of a resume without a prior written agreement does not create any express or implied contract between Crescent and the agency. Crescent will not pay any fees related to unsolicited resumes.

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