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Senior Clinical Bioinformatics Jobs (NOW HIRING)

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

... and clinical production. * Collaborates effectively to design and implement bioinformatics ... solutions. Gathers requirements and reports on progress to key stakeholders. * Leads statistical ...

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

Senior Scientist, Oncology

Menlo Park, CA · On-site

$107K - $147K/yr

... clinical, bioinformatics, and product groups. Preferred : • Experience working with oncology real-world datasets. • Experience applying large language models (LLMs) or retrieval-based AI systems ...

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation ... This role will report directly to a Senior Bioinformatics Scientist. What You'll Do: * Work with ...

... clinical microbiology. Today, worldwide more than 11000 employees are working on this permanent ... This role reports to our Senior Bioinformatician and does not include management of direct reports.

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Senior Clinical Bioinformatics information

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$84.5K

$102.3K

$119.5K

How much do senior clinical bioinformatics jobs pay per year?

As of Jun 13, 2026, the average yearly pay for senior clinical bioinformatics in the United States is $102,271.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $110,000.00 per year, depending on experience, location, and employer.

What is the highest paying job in bioinformatics?

Senior clinical bioinformatics roles, especially those involving leadership, data science, or specialized skills in genomics and machine learning, tend to be among the highest paying in the field. These positions often require advanced degrees, certifications, and experience with large datasets and bioinformatics tools, leading to higher salaries compared to entry-level roles.

What is the difference between Senior Clinical Bioinformatics vs Clinical Bioinformatics Specialist?

AspectSenior Clinical BioinformaticsClinical Bioinformatics Specialist
CredentialsTypically requires advanced degrees (Master's or PhD) and experienceUsually requires a relevant bachelor's or master's degree, with less emphasis on extensive experience
Work EnvironmentOften involved in leadership, project management, and strategic planning within healthcare or biotech companiesPrimarily focused on data analysis, pipeline development, and supporting clinical research teams
Employer & Industry UsageUsed in hospitals, biotech firms, and research institutions for overseeing clinical genomics projectsCommonly employed in clinical laboratories, research institutions, and healthcare settings for data processing

The main difference between Senior Clinical Bioinformatics and Clinical Bioinformatics Specialist lies in experience level, responsibilities, and scope. Senior roles typically involve leadership and strategic planning, while specialists focus on data analysis and technical support. Both roles require strong bioinformatics skills, but senior positions demand more extensive experience and often involve managing projects or teams.

What is the salary of a senior bioinformatician?

The salary of a senior clinical bioinformatician typically ranges from $90,000 to $130,000 annually, depending on experience, location, and employer. Professionals in this role often have strong skills in genomics, programming, and data analysis, and may work in healthcare, research institutions, or biotech companies.

What biology jobs pay over $100k?

Senior Clinical Bioinformatics roles often pay over $100,000 annually, especially with advanced skills in genomics, data analysis, and experience with tools like R or Python. Other high-paying biology-related jobs include biotech project managers, pharmaceutical scientists, and research directors, typically requiring advanced degrees and industry experience.

Is AI going to replace bioinformatics?

As a Senior Clinical Bioinformatics professional, AI is a tool that enhances data analysis and interpretation but is unlikely to fully replace the expertise required for designing experiments, validating results, and understanding complex biological systems. AI automates routine tasks and accelerates data processing, allowing bioinformaticians to focus on more complex problem-solving and interpretation. Continuous learning of programming skills and familiarity with AI tools are important for staying current in the field.
More about Senior Clinical Bioinformatics jobs
What cities are hiring for Senior Clinical Bioinformatics jobs? Cities with the most Senior Clinical Bioinformatics job openings:
What are the most commonly searched types of Clinical Bioinformatics jobs? The most popular types of Clinical Bioinformatics jobs are:
What states have the most Senior Clinical Bioinformatics jobs? States with the most job openings for Senior Clinical Bioinformatics jobs include:
Infographic showing various Senior Clinical Bioinformatics job openings in the United States as of June 2026, with employment types broken down into 1% Locum Tenens, 5% As Needed, 93% Full Time, and 1% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $102,271 per year, or $49.2 per hour.
Principal Scientist, Bioinformatics

Principal Scientist, Bioinformatics

Nkarta, Inc.

South San Francisco, CA • Hybrid

Other

Posted 28 days ago


Job description

Overview

Nkarta is seeking a highly motivated, collaborative, detail-oriented Principal Scientist to join our Translational Medicine team. This is a high-impact, hands-on leadership role for a senior bioinformatics scientist. The successful candidate will have deep expertise in single-cell and spatial omics technologies, along with experience in functional genomics and leading computational biology and/or bioinformatics programs in a biotech or pharmaceutical setting.

This individual will work collaboratively within Translational Medicine and cross-functionally to advance, support, and execute biomarker discovery, mechanism-of-action (MOA) investigations, and translational data analysis from clinical samples. A central focus of this role is to drive and execute on Nkarta's strategy for single-cell and spatial transcriptomics, leveraging scRNA-seq, spatial, and functional genomics approaches to drive translational insights, biomarker development, and clinical decision-making in early development.

Responsibilities

  • Lead and actively participate in the design and execution of computational strategies and hands-on analysis of clinical and biological datasets to support go/no-go decisions
  • Hands-on development and application of computational methods for single-cell and spatial transcriptomics to generate actionable translational insights from clinical samples
  • Establish scalable pipelines for multi-modal data integration across programs
  • Integrate and analyze functional genomics datasets (e.g., bulk RNA-seq) to generate mechanistic insights that inform translational and clinical strategies
  • Provide high-impact analyses with direct influence on clinical decision-making and visibility to senior leadership
  • Collaborate with senior leadership to define priorities, allocate resouces, and establish timelines aligned with company objectives
  • Partner with experimental scientists to design studies leveraging advanced omics approaches and interpret results
  • Ensure reproducibility, scalability, and data quality across bioinformatics pipelines
  • Communicate complex findings effectively to scientific and non-scientific stakeholders, including senior leadership

Qualifications

  • Deep expertise in single-cell and spatial transcriptomics analysis, including scRNA-seq and related high-dimensional omics datasets
  • Strong experience analyzing functional genomics and transcriptomic data (e.g., bulk RNA-seq, WES) to derive biological and translational insights
  • Strong foundation in biological sciences, with experience or interest in immunology and disease biology
  • Deep understanding of modern statistical and computational methods for high-dimensional data analysis
  • Proficiency in Python and/or R, with experience using relevant bioinformatics frameworks
  • Experience developing and maintaining scalable data analysis pipelines and working with cloud-based infrastructure (e.g., AWS)
  • Excellent communication and presentation skills, with the ability to influence cross-functional stakeholders and translate complex data into clear, actionable insights
  • Demonstrated experience managing external CROs and bioinformatics vendors
  • Proven leadership experience, including mentoring and developing scientific teams
  • Strong cross-functional collaboration skills and ability to translate computational insights into biological and clinical impact
  • Ability to work both independently and collaboratively in a fast-paced environment, with strong organizational skills and attention to detail

Education/Background

  • PhD in Biological Sciences, Computational Biology, Biostatistics, Bioinformatics, Genomics, or a closely related discipline with 5+ years of industry experience.

The common requirements of an office environment (computers, computer screens, workstations, etc.) apply. This role is based in the South San Francisco office, with hybrid work arrangements possible.