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Senior Cheminformatics Scientist Jobs (NOW HIRING)

Senior Computational Chemist

La Jolla, CA · On-site +1

$106K - $176K/yr

We are seeking a Senior Computational Chemist with a strong cheminformatics background and a proven track record of independent scientific delivery. The ideal candidate is expected to lead applied ...

$104 - $186/hr

Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a ... Senior Bioinformatics Research Scientist. Explore our exceptional benefits! St. Jude is an Equal ...

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Senior Cheminformatics Scientist information

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$66.5K

$110.5K

$164.5K

How much do senior cheminformatics scientist jobs pay per year?

As of Sep 5, 2026, the average yearly pay for senior cheminformatics scientist in the United States is $110,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,500.00 and $125,000.00 per year, depending on experience, location, and employer.

What is a senior cheminformatics scientist?

A Senior Cheminformatics Scientist is an experienced professional who applies computational and data analysis techniques to solve problems in chemistry, particularly in drug discovery and materials science. They work with large sets of chemical data, develop algorithms and models to predict molecular properties, and integrate informatics tools into research workflows. Typically, they collaborate with chemists, biologists, and IT specialists to manage data, design experiments, and optimize compounds for desired properties. Their work is crucial for accelerating scientific discoveries through the use of computational methods.

What are the key skills and qualifications needed to thrive as a senior cheminformatics scientist?

To thrive as a Senior Cheminformatics Scientist, you need a strong background in chemistry, data analysis, and computational methods, typically supported by a Ph.D. in chemistry, cheminformatics, or a related field. Expertise in programming languages such as Python or R, cheminformatics software (e.g., RDKit, OpenEye), and experience with chemical databases are essential. Strong problem-solving, collaboration, and communication skills help in translating complex data into actionable scientific insights and working effectively in multidisciplinary teams. These skills and qualifications are critical for driving innovative research, managing large chemical datasets, and supporting drug discovery or materials science projects.

What collaborative opportunities can a senior cheminformatics scientist expect when working with interdisciplinary teams?

As a Senior Cheminformatics Scientist, you'll frequently collaborate with medicinal chemists, biologists, data scientists, and software engineers to drive drug discovery projects. Your expertise bridges the gap between computational analysis and experimental science, often facilitating data-driven decision-making. Expect to participate in cross-functional meetings, contribute insights on molecular modeling, and support the integration of cheminformatics tools into research pipelines. This interdisciplinary environment fosters both scientific innovation and professional growth through continuous learning from diverse team members.

What is the difference between Senior Cheminformatics Scientist vs Chemoinformatics Analyst?

AspectSenior Cheminformatics ScientistChemoinformatics Analyst
Required CredentialsBachelor's/Master's/PhD in Chemistry, Bioinformatics, or related field; experience with cheminformatics toolsBachelor's/Master's in Chemistry, Bioinformatics, or related; focus on data analysis skills
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsData analysis teams, pharmaceutical R&D, biotech companies
Industry UsageUsed for drug discovery, compound management, and data interpretationUsed for data processing, chemical property analysis, and reporting

The Senior Cheminformatics Scientist typically has more advanced research responsibilities and leadership in chemical data analysis, while the Chemoinformatics Analyst focuses on data processing and reporting. Both roles require similar educational backgrounds but differ in scope and seniority.

More about Senior Cheminformatics Scientist jobs

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What are the most commonly searched types of Cheminformatics Scientist jobs?

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What states have the most Senior Cheminformatics Scientist jobs?

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What job categories do people searching Senior Cheminformatics Scientist jobs look for?

The top searched job categories for Senior Cheminformatics Scientist jobs are:

Infographic showing various Senior Cheminformatics Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 91% Full Time, 4% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $110,545 per year, or $53.1 per hour.

Senior Bioinformatics Research Scientist

St. Jude Children's Research Hospital

Memphis, TN • On-site

Full-time

Posted 19 days ago


St. Jude Children's Research Hospital rating

8.8

Company rating: 8.8 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

30th of 1,065 rated hospitals


Job description

St. Jude is seeking a Senior Bioinformatics Research Scientist for data science projects within the Center for Pharmacogenomics in the Department of Pharmacy and Pharmaceutical Sciences. In particular, this individual will focus on electronic health record (EHR)-driven phenotyping to support pharmacogenomics discovery research.
The successful candidate will be responsible for developing and implementing new informatics tools and resources to enhance phenotyping performance or enable deep phenotyping through terminology/ontology, natural language processing, and machine learning. The role involves working with large external biobank datasets such as All of US, eMERGE, TopMed, UK BioBank, as well internal EHR data.
This Bioinformatics Research Scientist will collaborate extensively with disease and/or drug experts (clinicians, clinician scientists, data scientists, and laboratory investigators) to co-develop phenotyping algorithms but is expected to serve as the domain expert in high-throughput phenotyping.
Demonstrated expertise in EHR-based phenotype extraction and curation are strongly preferred.
Responsibilities
oProvide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
oDeliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
oAssist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
oAssist in the evaluation and testing of new methods and technologies.
oContribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
oParticipate in the department's developmental projects and interdepartmental team projects.
Qualifications
oMinimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work experience in relevant area (e.g., bioinformatics, cheminformatics, statistics/computer science with a background in biological sciences or chemistry) (OR) Master's degree with 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
oSignificant experience in at least one programming or scripting language and at least one statistical package, with R preferred.
As one of the premier pediatric research institutions in the world, St. Jude Children's Research Hospital provides exceptional resources and a supportive environment for career development. In this position, the candidate will interact with leaders in pharmacogenomics and data science in general within and outside the institution and at national/international meetings. Innovation and independence are encouraged with the goal of providing flexibility and freedom in exploring new directions.
Job Responsibilities:
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Maintains regular and predictable attendance.
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.

Minimum Education and/or Training:
  • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
  • Master's degree or PhD preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
  • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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