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Remote Upstream Scientist Jobs (NOW HIRING)

2U

Data Scientist II

Washington, DC · On-site +1

Data modeling and validation Partner with Data Engineering to keep upstream sources trustworthy ... While this position is open to remote candidates across the U.S., we will prioritize those who live ...

2U

Data Scientist II

Crystal City, TX · On-site +1

Data modeling and validation Partner with Data Engineering to keep upstream sources trustworthy ... While this position is open to remote candidates across the U.S., we will prioritize those who live ...

Bayer

Associate Dir, Full Stack Data Scientist

Whippany, NJ · On-site +1

$59K - $59K/yr

Remote work arrangements will not be accommodated for this role. YOUR TASKS AND RESPONSIBILITIES ... Accountable to ensure process area capability issues are assessed upstream and downstream ...

Bayer

Associate Dir, Full Stack Data Scientist

Cambridge, MA · On-site +1

$64K - $65K/yr

Remote work arrangements will not be accommodated for this role. YOUR TASKS AND RESPONSIBILITIES ... Accountable to ensure process area capability issues are assessed upstream and downstream ...

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Remote Upstream Scientist information

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$83.5K

$127K

$171K

How much do remote upstream scientist jobs pay per year?

As of Jul 11, 2026, the average yearly pay for remote upstream scientist in the United States is $127,031.00, according to ZipRecruiter salary data. Most workers in this role earn between $109,000.00 and $143,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Upstream Scientist, and why are they important?

To thrive as a Remote Upstream Scientist, you need a strong background in biological sciences, process engineering, and data analysis, often supported by a relevant degree (such as biotechnology or chemical engineering) and experience in upstream bioprocessing. Familiarity with bioreactor systems, process control software, and data visualization tools is typically required, along with knowledge of industry standards like GMP. Strong problem-solving abilities, self-motivation, and effective virtual communication skills set top performers apart in remote environments. These competencies ensure precise experimental execution, robust data interpretation, and seamless collaboration with distributed teams, all critical for advancing biomanufacturing objectives.

What are some common challenges Remote Upstream Scientists face when collaborating with cross-functional teams?

Remote Upstream Scientists often work with process engineers, downstream scientists, and quality assurance teams spread across different locations and time zones. Effective communication and data sharing can be challenging, especially when troubleshooting experiments or scaling up processes. To overcome these hurdles, it's important to leverage collaborative digital tools, maintain detailed documentation, and schedule regular virtual meetings. Building strong relationships with team members and proactively addressing gaps in information flow can greatly enhance productivity and project outcomes.

What is the difference between Remote Upstream Scientist vs Remote Downstream Scientist?

AspectRemote Upstream ScientistRemote Downstream Scientist
CredentialsAdvanced degree in Geology, Petroleum Engineering, or related fieldDegree in Chemistry, Chemical Engineering, or related discipline
Work EnvironmentExploration, reservoir analysis, and resource assessmentRefining, product development, and marketing
Industry UsageOil & Gas exploration companies, energy firmsRefining companies, petrochemical industries
Search & Comparison IntentUnderstanding roles in exploration and resource extractionUnderstanding roles in product development and refining

The Remote Upstream Scientist focuses on exploration, reservoir analysis, and resource assessment within the oil and gas industry, requiring geoscience or engineering credentials. In contrast, the Remote Downstream Scientist works on refining processes, product development, and marketing, often with chemistry or chemical engineering backgrounds. Both roles are essential in the energy sector but differ in their focus areas and work environments.

What is a Remote Upstream Scientist?

A Remote Upstream Scientist is a professional who specializes in the early stages of biopharmaceutical or chemical production processes, known as upstream processing, and performs their duties remotely. Their work typically involves designing and optimizing cell culture or fermentation systems to produce desired biological products, such as proteins or vaccines. By working remotely, they leverage digital tools and data analysis to monitor, manage, and improve production processes without being physically present in the laboratory or manufacturing facility. This role requires strong technical expertise, communication skills, and the ability to collaborate with on-site teams.
More about Remote Upstream Scientist jobs
What cities are hiring for Remote Upstream Scientist jobs? Cities with the most Remote Upstream Scientist job openings:
What are the most commonly searched types of Upstream Scientist jobs? The most popular types of Upstream Scientist jobs are:
What states have the most Remote Upstream Scientist jobs? States with the most job openings for Remote Upstream Scientist jobs include:
What job categories do people searching Remote Upstream Scientist jobs look for? The top searched job categories for Remote Upstream Scientist jobs are:
Remote Upstream Scientist jobs near you
Infographic showing various Remote Upstream Scientist job openings in the United States as of July 2026, with employment types broken down into 33% Full Time, 33% Part Time, and 34% Contract. Highlights an 100% Remote job distribution, with an average salary of $127,031 per year, or $61.1 per hour.
Engineer, Biologics Purification, Upstream/Downstream/Tech Transfer - Remote (JP15407)

Engineer, Biologics Purification, Upstream/Downstream/Tech Transfer - Remote (JP15407)

3 Key Consulting

Cambridge, MA • On-site, Remote

$34 - $37/hr

Full-time

Posted 20 days ago

Job description

Job Title: Engineer, Biologics Purification, Upstream/Downstream/Tech Transfer - Remote (JP15407)
Location: Cambridge MA, Remote
Employment Type: Contract
Business Unit: Drug Substance Technology Engineering Group
Duration: 1+ years with possible extensions and/or conversion to permanent
Posting Date: 5/21/2026
Pay Rate: $34 - $37/hour W2
Notes: Remote (Any TZ - Local to Cambridge, MA is highly preferred.
3 Key Consulting is hiring an Engineer for a consulting engagement with our direct client, a leading global biopharmaceutical company.
Job Description:
Seeking a Process Development Engineer to join the Drug Substance Technology Engineering team at our client Cambridge site. Providing strong process engineering/ technology transfer support of human therapeutic drug substance products in clinical development through commercial production. Our mission is to translate developmental processes to commercial reality for patients through scientific expertise and engineering innovation. Knowledge of processes/equipment; scale-up factors, process deviations, quality attributes. GMP experience is a plus.
The Engineer will apply upstream and downstream process engineering knowledge in support of technology transfer and clinical/commercial drug substance manufacturing in both stainless and single-use formats. Will partner with manufacturing, quality, analytical, and bench scientists to support a highly dynamic technology transfer.
JOB RESPONSIBILITIES:
Under guidance of senior staff, the Engineer will perform the following:
  • Transfer processes for drug substance manufacturing and translate process improvements from the laboratory into manufacturing facilities
  • Provide technical support for successful scale-up, transfer of process technology, and for clinical and/or commercial manufacturing operation. Experience is technical report writing an expectation.
  • Assist in troubleshooting clinical and commercial runs
  • Execute data trending and statistical process analysis
  • Support technical direction for process-related deviations, CAPAs, and change controls
  • Identify and support process-related operational excellence opportunities
  • Represent process development and collaborates with other functions such as Manufacturing, Quality, and Regulatory.
  • Experience related to Process characterization for manufacturing of biologics highly preferred. This includes technical support for authoring and review of process characterization reports.

Why is the Position Open?
Supplement additional workload on team.
BASIC QUALIFICATIONS:
Master’s degree and 2 years of Engineering or Operations experience
Bachelor’s degree and 4 years of Engineering or Operations experience
Associate’s degree and 7 years of Engineering or Operations experience
High school diploma / GED and 8 years of Engineering or Operations experience
PREFERRED QUALIFICATIONS:
  • Master’s Degree in Chemical or Biochemical Engineering
  • 2+ years of Process Engineering experience preferably related to downstream/ purification of commercial cGMP manufacturing facilities
  • Background in biologics technology transfer into commercial facilities, new product introductions (NPIs)
  • Biologics purification process knowledge: Knowledge of upstream ( cell culture/bioreactor operations) or purification processes (chromatography, viral filtration/inactivation, ultrafiltration/diafiltration, and final fill. )/ equipment; scale-up factors, process deviations, quality attributes
  • Strong analytical capability, troubleshooting, and problem solving
  • Independently motivated with ability to multi-task and work in teams, especially if remote or hybrid.
  • Excellent written and verbal communication skills with technical writing and presentation experience. Experience in PC documentation, report reviews and technical writing preferred.
     
Top Must Have Skills:
  • Cell culture experience, Purification /downstream experience, process characterization experience
  • Nice to have:
    Monoclonal antibodies or mAbs 
    manufacturing or on floor support 

Day to Day Responsibilities:
Assist senior staff in technical writing, process tech transfer, data monitoring
Red Flags:
No experience, not enough experience in biopharma or biotech, no experience in cell culture/upstream, purification/downstream or technical report writing
Interview process:
Teams interview. Screening 30 minute Microsoft team's interview with me. Second round- Team's interview 30 minute each approximately with 3 other team members.
We invite qualified candidates to send your resume to resumes@3keyconsulting.com.  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.