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Entry Level Upstream Scientist Jobs (NOW HIRING)

... for life science researchers worldwide. All of our products are independently developed and ... This entry-level, hands-on role offers experience in both upstream bioprocessing and protein ...

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2026-2027 Petroleum Engineer - Full Time

Midland, TX ยท On-site +1

$118K - $138K/yr

... scientists, and / or software developers. Petroleum engineers develop technical skills in ... As a Petroleum Engineer, you could begin your career in Chevron's domestic Upstream operations or ...

2026-2027 Petroleum Engineer - Full Time

Minot, ND ยท On-site +1

$118K - $138K/yr

... scientists, and / or software developers. Petroleum engineers develop technical skills in ... As a Petroleum Engineer, you could begin your career in Chevron's domestic Upstream operations or ...

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Entry Level Upstream Scientist information

See salary details

$50.5K

$111.3K

$137.5K

How much do entry level upstream scientist jobs pay per year?

As of Jul 31, 2026, the average yearly pay for entry level upstream scientist in the United States is $111,343.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $137,000.00 per year, depending on experience, location, and employer.

What is the difference between Entry Level Upstream Scientist vs Entry Level Reservoir Engineer?

AspectEntry Level Upstream ScientistEntry Level Reservoir Engineer
Required CredentialsBachelor's degree in Geology, Geophysics, or related fieldBachelor's degree in Petroleum Engineering, Reservoir Engineering, or related field
Work EnvironmentLaboratories, field data analysis, seismic interpretationReservoir modeling, production optimization, field development planning
Industry UsageOil & gas exploration and production companies, geoscience firmsOil & gas operators, E&P companies, consulting firms

While both roles are entry-level positions in the upstream oil and gas sector, an Entry Level Upstream Scientist primarily focuses on geoscience data analysis and exploration, whereas an Entry Level Reservoir Engineer concentrates on reservoir performance and production optimization. Both require relevant degrees and are essential in the exploration and production process, but they differ in daily tasks and technical focus.

More about Entry Level Upstream Scientist jobs
What are the most commonly searched types of Upstream Scientist jobs? The most popular types of Upstream Scientist jobs are:
What job categories do people searching Entry Level Upstream Scientist jobs look for? The top searched job categories for Entry Level Upstream Scientist jobs are:
Infographic showing various Entry Level Upstream Scientist job openings in the United States as of July 2026, with employment types broken down into 87% Full Time, 10% Part Time, 1% Temporary, and 2% Contract. Highlights an 96% Physical, 1% Hybrid, and 3% Remote job distribution, with an average salary of $111,343 per year, or $53.5 per hour.

Upstream Associate

SIGNOBIO INC

Houston, TX โ€ข On-site

Full-time

Posted yesterday

New


Job description

About Us

Sino Biological is a world-renowned reagent supplier and contract research organization, listed on ChiNext of the Shenzhen Stock Exchange (301047 Sino Biological Inc.). Our core technology platform is an in-house-developed mammalian cell-based recombinant expression system that leverages proprietary reagents and processes for high-efficiency production of antigens and antibodies. We are headquartered in Beijing, China, with a U.S. base in the Greater Philadelphia area, an office and bioprocessing center in Houston, Texas, and subsidiaries in Frankfurt, Germany, and Kawasaki, Japan. Sino Biological is committed to providing high-quality recombinant protein and antibody reagents and to being a one-stop technical services shop for life science researchers worldwide. All of our products are independently developed and produced. In addition, we offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.


Job Description

This entry-level, hands-on role offers experience in both upstream bioprocessing and protein quality control (QC) for individuals looking to launch their industrial biotechnology career. As an Associate, Upstream, you’ll assist in recombinant protein and antibody expression using mammalian cell cultures, while also supporting QC testing to evaluate product quality. You’ll work closely with project scientists, contributing to aseptic cell culture, transfection, harvest, and analytical testing, all with an emphasis on accuracy, documentation, and collaboration across teams. Flexibility is key, including potential weekend work, early/late weekday shifts, and participation in essential lab maintenance or cross-functional support tasks as needed.


Responsibilities
  • Perform recombinant protein expression using mammalian systems such as HEK293 and CHO.

  • Execute upstream workflows including cell thawing, expansion, transfection, and harvesting.

  • Maintain lab cleanliness, including biosafety cabinets, incubators, and shared spaces.

  • Handle and maintain cell cultures using proper aseptic techniques.

  • Conduct protein quality control assays, including SDS-PAGE, HPLC-SEC, endotoxin testing, and UV-Vis measurements.

  • Record data and observations in electronic lab notebooks accurately and promptly.

  • Assist with media/reagent preparation, equipment setup, and maintenance tasks.

  • Support instrument calibration, troubleshooting, and lab upkeep.

  • Collaborate with downstream and cross-functional teams to ensure smooth project execution.

  • Conduct product aliquoting to meet delivery timelines.

  • Adhere to all safety and PPE protocols under federal, state, and local regulations.


Requirements
  • Bachelor’s degree (BA or BS) in Biology, Cell Biology, Biochemistry, Biotechnology, or a related field.

  • 0–3 years of lab experience with mammalian cell culture; HEK293 and CHO preferred.

  • Familiarity with suspension culture and aseptic techniques.

  • Basic experience with analytical assays such as SDS-PAGE, HPLC-SEC, UV-Vis, or endotoxin testing is a plus.

  • Strong attention to detail, documentation, and troubleshooting skills.

  • Flexible and adaptable to varying schedules or project demands.

  • Effective communication skills and the ability to work collaboratively in a team-oriented environment.

  • Must be able to lift and move 25–50 lbs as needed.


Why Join Us at C4B?

Working at Sino Biological’s C4B facility isn’t just another lab job, it’s a chance to be part of something bigger. Here are just a few of the unique benefits of our Houston site:

  • World-class location: Be part of the Texas Medical Center, the largest medical complex in the world, where biotech innovation thrives.

  • Beautiful work environment: Enjoy a brand-new, state-of-the-art facility designed for collaboration and scientific excellence.

  • Free onsite parking: Skip the hassle and expense of parking in the Medical Center, we’ve got you covered.

  • Free onsite gym: Stay active and energized with convenient access to fitness facilities right at work.

  • Career growth opportunities: Learn directly from industry professionals while growing your career at a global biotech company.

  • Supportive team culture: A welcoming, team-first workplace that values diversity, collaboration, and professional development.


Join Us in Advancing Scientific Innovation!

Be a part of Sino Biological and contribute to groundbreaking scientific advancements worldwide. Apply today to join our dynamic team!

Sino Biological is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.


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