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Remote Software Engineer Startup Jobs in Colorado

Sr. Software Engineer - ML Systems

Denver, CO ยท On-site +1

$176K - $206K/yr

While we are mostly a remote company, travel is required for some team meetings and cross function ... About the Opportunity We are seeking a Senior Software Engineer to design, build, deploy, monitor ...

Senior Blockchain Engineer

Almont, CO ยท On-site +1

$157K - $178K/yr

... software development. Founded in 2020, the company helps startups, enterprises, and SMBs build ... UseBlocky combines deep technical expertise with a remote-first culture, empowering teams to ...

Software Engineer - Python / Django

Centennial, CO ยท On-site +1

$114K - $172K/yr

... remote option.) Job Summary This job involves collaborative design and development of software ... It also involves mentoring junior engineers, ensuring quality with Quality Assurance, and providing ...

Principal Software Development Engineer

Denver, CO ยท On-site +1

$139K - $186K/yr

PRINCIPAL SOFTWARE DEVELOPMENT ENGINEER- DEVOPS | REMOTE | US Travel obsessed? Big tech fan? Hey, you're in good company. If you want to be part of the industry that makes the world go round, then ...

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Remote Software Engineer Startup information

What is the difference between Remote Software Engineer Startup vs Remote Software Engineer Corporate?

AspectRemote Software Engineer StartupRemote Software Engineer Corporate
CredentialsBachelor's in CS or related field, coding skillsBachelor's in CS or related field, coding skills
Work EnvironmentFast-paced, flexible, small teamsStructured, larger teams, established processes
Employer & IndustryStartups, tech or innovative sectorsLarge corporations, diverse industries
Search & Comparison IntentFocus on startup culture, agilityFocus on stability, resources

Remote Software Engineer Startup roles typically involve working in dynamic, fast-growing environments with smaller teams, emphasizing innovation and flexibility. In contrast, Remote Software Engineer Corporate positions are more structured, with established processes and larger teams, offering stability and resources. Both roles require similar technical credentials but differ in work environment and company size.

What is a remote software engineer at a startup?

A remote software engineer at a startup is a professional who designs, develops, and maintains software applications while working from a location outside the company's physical office. These engineers use online collaboration tools to communicate with their team and contribute to fast-paced, innovative projects typical of startup environments. They are responsible for writing code, fixing bugs, and sometimes contributing to product design and strategy. Working remotely requires strong self-motivation, excellent communication skills, and the ability to adapt to rapidly changing situations common in startups.

What are some common challenges faced by remote software engineers working at startups, and how can they be addressed?

Remote software engineers at startups often encounter challenges such as navigating ambiguous requirements, adapting to fast-changing priorities, and maintaining effective communication across distributed teams. To address these, it's important to proactively seek clarification from product managers or team leads, embrace agile methodologies to stay flexible, and utilize collaboration tools like Slack, Jira, and GitHub for transparent communication. Building a habit of regular check-ins and documentation can also help ensure alignment and prevent misunderstandings in a dynamic startup environment.

What are the key skills and qualifications needed to thrive as a Remote Software Engineer at a startup, and why are they important?

To thrive as a Remote Software Engineer at a startup, you need strong programming skills (such as in Python, JavaScript, or Java), problem-solving abilities, and typically a degree in computer science or related experience. Familiarity with version control systems like Git, cloud platforms (e.g., AWS, Azure), and agile development tools is essential. Outstanding communication, self-motivation, and adaptability are vital soft skills for collaborating remotely and handling dynamic startup environments. These skills ensure you can deliver quality code, work effectively across distributed teams, and adapt quickly to changing priorities in a fast-paced startup setting.
What are the most commonly searched types of Software Engineer Startup jobs in Colorado? The most popular types of Software Engineer Startup jobs in Colorado are:
What job categories do people searching Remote Software Engineer Startup jobs in Colorado look for? The top searched job categories for Remote Software Engineer Startup jobs in Colorado are:
What cities in Colorado are hiring for Remote Software Engineer Startup jobs? Cities in Colorado with the most Remote Software Engineer Startup job openings:
Infographic showing various Remote Software Engineer Startup job openings in Colorado as of July 2026, with employment types broken down into 91% Full Time, 6% Part Time, and 3% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution.
Sr. Software Engineer - ML Systems

Sr. Software Engineer - ML Systems

Cleerly

Denver, CO โ€ข On-site, Remote

$176K - $206K/yr

Full-time

Posted 27 days ago


Job description

About Cleerly

We're Cleerly โ€“ a healthcare company that's revolutionizing how heart disease is diagnosed, treated, and tracked. We were founded in 2017 by one of the world's leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and sales leaders. We raised $223M in Series C funding in 2022 which has enabled rapid growth and continued support of our mission. In December 2024 we received an additional $106M in a Series C extension funding. Most of our teams work remotely and have access to our offices in Denver, Colorado, New, York, New York, Dallas, Texas, and Lisbon, Portugal with some roles requiring you to be on-site in a location.

Cleerly has created a new standard of care for heart disease through value-based, AI-driven precision diagnostic solutions with the goal of helping prevent heart attacks. Our technology goes beyond traditional measures of heart disease by enabling comprehensive quantification and characterization of atherosclerosis, or plaque buildup, in each of the heart arteries. Cleerly's solutions are supported by more than a decade of performing some of the world's largest clinical trials to identify important findings beyond symptoms that increase a person's risk of heart attacks.

At Cleerly, we collaborate digitally and use a wide variety of systems. Our people use Google Workspace (GMail, Drive, Docs, Sheets, Slides), Slack, Confluence/Jira, and Zoom Video, prior experience in these areas is a plus. Role or department specific technology needs may vary and will be listed as requirements in the job description.

While we are mostly a remote company, travel is required for some team meetings and cross function projects typically once per month or once per quarter, for some roles like sales or external facing roles travel could be up to 90% of the time.
Cleerly is committed to providing safe and effective medical software that meets customer needs and our intended use. The adherence to all applicable regulatory and statutory requirements establishes a clear framework for setting measurable quality objectives. Our commitment to continually improving our products and processes proactively manages risks, ensuring ongoing compliance throughout the entire software lifecycle. Understanding this role's relevance and importance is critical to achieving Cleerly's quality objectives.

About the Opportunity

We are seeking a Senior Software Engineer to design, build, deploy, monitor, and optimize production-ready ML services in regulated healthcare. You will work hands-on to package, test, orchestrate, deploy, and maintain ML models, improve workflows, and implement CI/CD and automated testing to ensure reliability, performance, and faster delivery of business value.

Responsibilities
  • Design, build, and deploy scalable AI/ML services with clear service boundaries, making pragmatic trade-offs across performance, maintainability, security, and long-term extensibility.

  • Own full lifecycle delivery of complex features from architectural planning and API design to implementation and post-release observability.

  • Define and enforce robust verification and validation for AI services including unit, integration, and end-to-end testing to ensure reliability of code in production and compliance with our Quality Management System and regulatory standards.

  • Integrate CI/CD and MLOps practices for automated model builds, testing, and deployment.

  • Translate product requirements into well-defined technical designs proactively shaping implementation details.

  • Contribute to the necessary technical documentation required for regulatory submissions.

  • Collaborate cross functionally to reduce knowledge silos and ensure continuity in critical systems through cross-training and documentation.

Requirements
  • Bachelor's or Master's degree in Computer Science, Software Engineering, or related field

  • 7+ years of software engineering experience, with expertise in AI production systems (Python, PyTorch) and data services (SQL, Postgres, NoSQL, Redis or similar).

  • Experience with unit, integration testing for ML models, including data validation, correctness checks, and reproducibility.

  • Experience with CI/CD, Orchestration tools (Airflow, MLflow, Kubernetes, Terraform) and ML/data platforms(SageMaker, Databricks, Unity Catalog, Snowflake/Snowpark) to build scalable ML data pipelines and model workflows.

  • Strong collaboration skills to work effectively with ML scientists, engineers, and regulatory teams.

  • Comfortable operating in ambiguity and driving clarity across product, engineering, and business stakeholders.

This role is eligible for a 15% target annual bonus, resulting in the following base salary and Total Target Compensation (TTC) ranges:

  • Base Salary: $153,000 - $179,000
  • TTC: $176,000 - $206,000

*Total Target Compensation (TTC): Total Cash Compensation (including base pay, variable pay, commission, bonuses, etc.) Additionally, stock options, paid benefits, and employee perks are part of your total rewards.

Working at Cleerly takes HEART. Discover our Core Values:

  • H: Humility- be a servant leader
  • E: Excellence- deliver world-changing results
  • A: Accountability- do what you say; expect the same from others
  • R: Remarkable- inspire & innovate with impact
  • T: Teamwork- together we win

Don't meet 100 percent of the qualifications? Apply anyway and help us diversify our candidate pool and workforce. We value experience, whether gained formally or informally on the job or through other experiences. Job duties, activities and responsibilities are subject to change by our company.

OUR COMPANY IS AN EQUAL OPPORTUNITY EMPLOYER. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation.

For more information see our Privacy Policy (https://cleerlyhealth.com/privacy-policy). All official emails will come from @cleerlyhealth.com email accounts.

#Cleerly