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Remote Senior Software Developer Jobs in Columbus, OH

Huntington

Senior Full Stack Developer

Columbus, OH · On-site +1

$70K - $140K/yr

  • Medical

  • Life

  • Retirement

  • PTO

Full SDLC experience with software development. * 3+ years of experience in developing REST APIs in ... Remote roles will also have the opportunity to come together in our offices for moments that matter.

Huntington

Senior Full Stack Developer

Columbus, OH · On-site +1

$70K - $140K/yr

  • Medical

  • Life

  • Retirement

  • PTO

Full SDLC experience with software development. * 3+ years of experience in developing REST APIs in ... Remote roles will also have the opportunity to come together in our offices for moments that matter.

Nationwide

Consultant, Software Engineer

Columbus, OH · On-site +1

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... developer productivity. The most important technical competencies for this role are hands-on ... OneNationwide Plaza, Columbus OH, 43215 Work schedule: 2 days in office, 3 days remote. This role ...

Wendy's

Sr Engineer - Platform

Dublin, OH · Remote

$93K - $158K/yr

  • Retirement

Work closely with operations and software engineering teams to design and implement scalable and ... Kubernetes administration experience a plus Expected Work Location (Remote) : It is expected that ...

The Wendy's Company

Sr Engineer - Platform

Dublin, OH · Remote

$93K - $158K/yr

  • Retirement

Work closely with operations and software engineering teams to design and implement scalable and ... Kubernetes administration experience a plus Expected Work Location (Remote) : It is expected that ...

Bread Financial

Senior Staff Agentic AI Engineer

Columbus, OH · On-site +1

$102K - $139K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Job Summary The Senior Staff Software Engineer - Agentic AI will design and deliver core agent ... Normal office environment. (Remote or Hybrid), 3 to 4 days per month are required in office if ...

SmartIPlace

.Net Developer[Hybrid]

Columbus, OH · Remote

Hybrid/remote Interview: Web Cam Interview Only Prior experience with HR applications Client is ... Senior Developer to refactor an existing custom .net/C# Human Resources software suite hosted on ...

Loop

Software Engineer

Columbus, OH · Remote

$125K - $165K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Loop is looking for a full-stack Software Engineer to contribute directly to the design ... Austin, TX; Los Angeles, CA; or fully remote. Our Tech Stack: PHP/Laravel, Vue.js, MySQL, DynamoDB ...

Loop

Software Engineer

Columbus, OH · Remote

$125K - $165K/yr

Loop is looking for a full-stack Software Engineer to contribute directly to the design ... Austin, TX; Los Angeles, CA; or fully remote. Our Tech Stack: PHP/Laravel, Vue.js, MySQL, DynamoDB ...

Path Robotics

Software Engineer, Fleet Platform

Columbus, OH · On-site +1

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

This role requires a unique blend of developer skills and platform operations experience to build ... You have hands-on experience or a strong interest in tools for remote robotics tooling (e.g ...

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Remote Senior Software Developer information

See Columbus, OH salary details

$14

$59

$84

How much do remote senior software developer jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for remote senior software developer in Columbus, OH is $59.63, according to ZipRecruiter salary data. Most workers in this role earn between $50.62 and $66.88 per hour, depending on experience, location, and employer.

What is a remote senior software developer?

Remote Senior Software Developers are experienced software engineers who work from locations outside of a traditional office, often from home or other remote settings. They design, develop, test, and maintain complex software systems, lead technical projects, and mentor junior developers. In addition to deep technical expertise, they are skilled in communication and collaboration tools to coordinate effectively with distributed teams. Their responsibilities also include making architectural decisions and ensuring best practices in software development. Remote work allows them flexibility in location and often in working hours.

How does a remote senior software developer maintain effective collaboration with distributed team members?

As a Remote Senior Software Developer, collaboration typically relies on a mix of asynchronous communication tools (like Slack, Jira, or Trello) and scheduled video meetings to align on project goals and progress. You'll need to proactively document your work, share updates, and participate in regular code reviews to keep everyone on the same page. Building trust and rapport with team members across different time zones is essential, so clear communication and flexibility are key. Many organizations also encourage virtual team-building activities to foster a sense of connection despite the physical distance.

What are the key skills and qualifications needed to thrive as a remote senior software developer, and why are they important?

To thrive as a Remote Senior Software Developer, you need advanced programming expertise, architectural knowledge, and a strong background in computer science or a related field, often supported by relevant degrees or certifications. Familiarity with development frameworks, version control systems like Git, cloud platforms such as AWS or Azure, and tools for remote collaboration are typically required. Excellent communication, self-motivation, and problem-solving skills set standout developers apart in distributed teams. These abilities ensure high-quality software delivery, effective remote teamwork, and adaptability in a fast-evolving technological landscape.

What is the difference between Remote Senior Software Developer vs Remote Software Engineer?

AspectRemote Senior Software DeveloperRemote Software Engineer
CredentialsBachelor's degree in CS or related field; extensive experienceBachelor's degree in CS or related field; relevant experience
Work EnvironmentCollaborates on complex projects, often leads technical effortsDevelops software solutions, collaborates with teams
Industry UsageCommon in tech companies, startups, and enterprise firmsWidely used across tech, finance, healthcare, and more
Search & Comparison IntentOften compared for seniority, responsibilities, and experienceCompared for scope of work and technical skills

Remote Senior Software Developers typically have more experience and lead complex projects, while Remote Software Engineers focus on developing and implementing software solutions. Both roles require strong technical skills and are prevalent in various industries, but the senior role emphasizes leadership and strategic input.

What are popular job titles related to Remote Senior Software Developer jobs in Columbus, OH?

For Remote Senior Software Developer jobs in Columbus, OH, the most frequently searched job titles are:

What job categories do people searching Remote Senior Software Developer jobs in Columbus, OH look for?

The top searched job categories for Remote Senior Software Developer jobs in Columbus, OH are:

What cities near Columbus, OH are hiring for Remote Senior Software Developer jobs?

Cities near Columbus, OH with the most Remote Senior Software Developer job openings:

Remote Senior Software Developer jobs near you
Infographic showing various Remote Senior Software Developer job openings in Columbus, OH as of August 2026, with employment types broken down into 84% Full Time, 5% Part Time, and 11% Contract. Highlights an 5% Hybrid, and 95% Remote job distribution, with an average salary of $124,021 per year, or $59.6 per hour.

Senior AI Full stack Software Engineer

McKesson

Columbus, OH • Remote

$131K - $218K/yr

Full-time

This job post has expired today. Applications are no longer accepted.

McKesson rating

7.9

Company rating: 7.9 out of 10

Based on 210 frontline employees who took The Breakroom Quiz

47th of 86 rated pharmaceutical

Job description

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

We are seeking a highly skilled and experienced Senior AI Full Stack Software Engineer to join our innovative team at CMM. This role involves designing, developing, and deploying end-to-end AI-powered solutions, from robust backend services to intuitive user interfaces, to enhance our healthcare and decision-making platforms.

Key Responsibilities

  • Lead AI-Driven Healthcare Solutions: Design and deploy AI applications that support decision-making, patient engagement, and operational efficiency.

  • Integrate AI into EHRs and Clinical Systems: Build scalable systems that incorporate LLMs, voice/image recognition, and document parsing into existing healthcare IT infrastructure.

  • Develop and Optimize Data Pipelines: Ensure secure, HIPAA-compliant data pipelines for training and deploying AI models using structured and unstructured healthcare data (e.g., clinical notes, imaging, lab results).

  • Model Evaluation and Compliance: Apply rigorous evaluation metrics (e.g., sensitivity, specificity, AUC-ROC) and ensure models meet regulatory and ethical standards.

  • Mentor and Lead: Guide junior engineers and contribute to the strategic direction of AI initiatives within the organization.

  • Rapid AI prototyping and iteration with product representatives to vet multiple concepts

Minimum Qualifications

  • 10+ years of software engineering experience, with 4+ years in AI/ML development.

  • B.S. degree in Computer Science or related engineering discipline, or equivalent experience

Critical Skills

  • 2+ years of experience building AI solutions in healthcare or life sciences.

  • Deep understanding of healthcare data standards (e.g., HL7, FHIR) and compliance frameworks (e.g., HIPAA, GDPR).

  • Healthcare AI Expertise: Proven ability to build AI models for clinical NLP, medical imaging, patient risk stratification, and care personalization.

  • LLM & RAG Systems: Skilled in building retrieval-augmented generation systems using tools likePydantic, Semantic Kernel,LangChain,LlamaIndex, and vector databases.

  • Experienced in creating custom AI agents or spec-driven tools.

  • Experience writing skills for Claude, Copilot, Codex etc.

  • Prompt Engineering & Optimization: Advanced techniques for prompt tuning, caching, and benchmarking.

  • Full Stack Development: Proficiency in Python, Node.js, and modern web frameworks.

Preferred Skills

  • Cloud & DevOps: Experience with secure cloud environments (AWS/GCP/Azure), containerization (Docker, Kubernetes), and CI/CD pipelines.

  • AI Tooling: Familiarity with OpenAI, Hugging Face,PyDanticAI, TensorFlow,PyTorch, and healthcare-specific AI libraries.

  • Communication & Leadership: Ability to communicate complex AI concepts to clinical and executive stakeholders and lead cross-functional teams.

  • Experience mentoring and developing juniors in development an AI concepts/best practices.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$131,000 - $218,300

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

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