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Remote Senior Mes Engineer Jobs (NOW HIRING)

Inteldot

Sr MES Engineer - PAS-X (Remote)

Raritan, NJ · Remote

$106K - $137K/yr

Position Overview We are seeking an experienced Senior MES Engineer with extensive expertise in Werum PAS-X Manufacturing Execution System (MES) implementations within regulated pharmaceutical and ...

Inteldot

Sr MES Engineer - PAS-X

Raritan, NJ · On-site +1

$106K - $137K/yr

Position Overview We are seeking an experienced Senior MES Engineer with extensive expertise in Werum PAS-X Manufacturing Execution System (MES) implementations within regulated pharmaceutical and ...

Inteldot

Sr MES Engineer - PAS-X

Raritan, NJ · On-site +1

$106K - $137K/yr

Position Overview We are seeking an experienced Senior MES Engineer with extensive expertise in Werum PAS-X Manufacturing Execution System (MES) implementations within regulated pharmaceutical and ...

TEKsystems

MES Engineer

Boston, MA · Remote

$50 - $70/hr

We are seeking a MES Engineer to join our team remotely! Responsibilities: * Support and enhance ... remote position. Application Deadline This position is anticipated to close on Sep 9, 2026. About ...

Digital Links Inc

Senior Terraform Engineer

Springfield, MO · Remote

$111K - $151K/yr

Remote Senior Terraform Engineer who will lead the design, development, and governance of Infrastructure as Code (IaC) using Terraform in a cloud environment. This person will build and maintain ...

Harris

(Remote) Senior Software Engineer

Carolina, RI · Remote

$123K - $162K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$117K - $154K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$121K - $160K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$101K - $133K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

(Remote) Senior Software Engineer

Louisiana, MO · Remote

$108K - $142K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$107K - $142K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$116K - $152K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$104K - $138K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

(Remote) Senior Software Engineer

Florida, NY · Remote

$126K - $166K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

(Remote) Senior Software Engineer

Iowa, LA · Remote

$108K - $143K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

(Remote) Senior Software Engineer

Alabama, NY · Remote

$110K - $145K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

(Remote) Senior Software Engineer

Louisiana, MO · Remote

$108K - $142K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

Harris

$104K - $138K/yr

The Senior Software Engineer, RPG is a hands-on technical leader responsible for complex IBM i/RPG ... This remote role welcomes candidates anywhere in the US. Salary: 110K - 135K What your impact will ...

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How much do remote senior mes engineer jobs pay per year?

As of Aug 31, 2026, the average yearly pay for remote senior mes engineer in the United States is $126,557.00, according to ZipRecruiter salary data. Most workers in this role earn between $104,500.00 and $143,500.00 per year, depending on experience, location, and employer.
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Infographic showing various Remote Senior Mes Engineer job openings in the United States as of August 2026, with employment types broken down into 93% Full Time, 3% Part Time, and 4% Contract. Highlights an 86% Physical, 5% Hybrid, and 9% Remote job distribution, with an average salary of $126,557 per year, or $60.8 per hour.

Sr MES Engineer - PAS-X (Remote)

Inteldot

Raritan, NJ • Remote

$106K - $137K/yr

Full-time

This job post has expired today. Applications are no longer accepted.

Job description

Position Overview

We are seeking an experienced Senior MES Engineer with extensive expertise in Werum PAS-X Manufacturing Execution System (MES) implementations within regulated pharmaceutical and biotechnology manufacturing environments. This role will be responsible for designing, configuring, deploying, and supporting PAS-X solutions that enable digital manufacturing, electronic batch records (EBR), and compliant shop floor execution while ensuring alignment with business, manufacturing, and regulatory requirements.

Key Responsibilities
  • Lead the design, configuration, implementation, and support of Werum PAS-X MES solutions for pharmaceutical manufacturing operations.
  • Collaborate with Manufacturing, Process Engineering, Quality, Validation, Automation, and IT teams to translate business and process requirements into MES functional solutions.
  • Configure PAS-X Master Batch Records (MBRs), workflows, electronic forms, material management, equipment integration, and process parameters.
  • Support end-to-end MES deployment activities, including requirements gathering, solution design, configuration, testing, commissioning, and production support.
  • Develop and review functional specifications, design documents, configuration specifications, and technical documentation.
  • Troubleshoot MES issues, perform root cause analysis, and implement sustainable corrective actions.
  • Support system integration with ERP, LIMS, automation (PLC/SCADA), historians, and other manufacturing systems.
  • Participate in FAT, SAT, commissioning, qualification, and validation activities to ensure regulatory compliance.
  • Ensure MES solutions comply with GxP requirements, 21 CFR Part 11, Annex 11, and Data Integrity principles.
  • Lead change requests, system enhancements, software upgrades, and continuous improvement initiatives.
  • Provide technical leadership during technology transfers, new product introductions, and commercial manufacturing support.
  • Mentor junior engineers and provide technical guidance to project teams and business stakeholders.
Required Qualifications
  • Bachelor's degree in Engineering, Computer Science, Information Technology, or related technical discipline.
  • 7+ years of experience implementing and supporting Manufacturing Execution Systems within regulated pharmaceutical or biotechnology environments.
  • 5+ years of hands-on experience with Werum PAS-X MES, including system configuration and deployment.
  • Strong understanding of pharmaceutical manufacturing processes, electronic batch records (EBR), and digital manufacturing concepts.
  • Experience configuring PAS-X Master Batch Records (MBRs), workflows, process logic, and manufacturing recipes.
  • Working knowledge of GAMP 5, FDA 21 CFR Part 11, Annex 11, and Data Integrity requirements.
  • Experience supporting commissioning, qualification, validation, and production go-live activities.
  • Strong analytical and problem-solving skills with the ability to troubleshoot complex MES issues.
  • Excellent communication, documentation, and stakeholder management skills.
  • Ability to manage multiple priorities in a fast-paced manufacturing environment.
Preferred Qualifications
  • Experience supporting biologics, sterile manufacturing, cell & gene therapy, or vaccine production.
  • Experience integrating PAS-X with SAP ERP, LIMS, DeltaV, PI Historian, OPC, or other manufacturing systems.
  • Knowledge of ISA-95 manufacturing integration standards.
  • Experience with software development lifecycle (SDLC), Agile, Waterfall, or Hybrid project methodologies.
  • Previous participation in global or multi-site PAS-X implementations.
  • Experience supporting regulatory inspections and customer audits.
  • Knowledge of serialization, track-and-trace, and digital manufacturing initiatives.
  • Experience with cloud or hybrid manufacturing IT architectures is a plus.