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Remote Python Startup Jobs (NOW HIRING)

twenty80.io

Senior Full Stack Software Engineer

Boston, MA · On-site +1

$160K - $210K/yr

Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI) * Databases: PostgreSQL ... flexible PTO; standard startup benefits * Work Model: Hybrid or remote-friendly depending on ...

SmarterDx

Senior Software Engineer, Machine Learning

$190/hr

This role is fully remote within the US** What You'll Do * Build and scale machine-learning driven ... Strong proficiency in Python and SQL, with experience in machine learning libraries (Pytorch ...

Chasm Select

Senior Machine Learning Engineer

Manhattan, NY · On-site +1

$150K - $180K/yr

Remote (For Non-Local) or Hybrid (Local to NYC area) Position Summary: Join our mission to infuse ... Most importantly, we are a mission-oriented, high-growth startup and we are looking for folks that ...

ICONSTAFF

Senior Backend Engineer

Boston, MA · Remote

$160K - $240K/yr

Strong Python skills and experience with large-scale systems * Solid understanding of APIs ... Startup or full-stack experience Additional Info * Fully remote (U.S. only) * Competitive salary ...

New

OSI Engineering, Inc.

Senior AI Engineer

Cupertino, CA · On-site +1

$58 - $68/hr

Strong TypeScript development experience ( Python a plus) * Experience building AI-powered ... Startup or highly autonomous engineering experience preferred Education & Experience * Bachelor ...

Cypress HCM

Full Stack Developer

Atlanta, GA · On-site +1

$80K - $100K/yr

Remote from Atlanta, GA | In-office time (ATDC) will be available to you but isn't mandated ... Working in a highly autonomous environment at an early-stage startup with financial backing and ...

Pipe Technologies

Senior Software Engineer

$150K - $220K/yr

We are hiring a Senior Backend Engineer to work in our Go, Python, and Postgres stack. You'll work ... You want to join a remote-first startup and make an impact. * You want to be part of a team that ...

Hired Recruiters

Senior DevOps Engineer

Austin, TX · On-site +1

$128K - $165K/yr

Remote * Salary $150k - $200k * Seed Company * Skills: Ansible, Bash, Python, Terraform, Docker ... Experience working at a venture-backed early-stage startup * B.S., or M.S., in Computer Science or ...

SmarterDx

Staff Software Engineer, Full Stack

$230K - $250K/yr

This role is fully remote within the US** What You'll Do * Design, build and launch new multi ... Expertise in TypeScript, React, and Python * Experience working on software that aids in decision ...

Cloudacio

Data Engineer (Contract) (Remote)

Manhattan, NY · Remote

$126K - $151K/yr

Core Skills: * Strong proficiency in Python * Experience with SQL and NoSQL databases (e.g ... Previous consulting or startup environment experience. * Ability to independently handle customer ...

Miller Cooper

QA Automation Engineer

Chicago, IL · Remote

$85K - $95K/yr

Join a startup company with over 100 healthcare clients and growing! * Fully remote role that has a ... Experience with Python or JavaScript * Strong debugging skills * Legal authorization to work in the ...

Miller Cooper

Integrations Engineer

Chicago, IL · Remote

$85K - $95K/yr

Join a startup company with over 100 healthcare clients and growing! * Fully remote role that has a ... Python or scripting experience preferred * Azure or cloud platform experience preferred * SFTP and ...

Transparent Hiring

$106K - $128K/yr

... in startup environments (fast-moving, hands-on, limited resources) * Strong skills in Python and ... Remote-first across Germany and the US (offices available). * Relocation to Germany is supported by ...

W3 Global Sourcing

Lead Engineer

San Francisco, CA · On-site +1

$120K - $159K/yr

Open-source contributions in TypeScript, Node.js, Python, Go, or Rust. * Prior 0-1 startup ... USA remote. * US-based candidates only. * Visa sponsorship is not available. Apply Now!

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Remote Python Startup information

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How much do remote python startup jobs pay per hour?

As of Jun 13, 2026, the average hourly pay for remote python startup in the United States is $58.62, according to ZipRecruiter salary data. Most workers in this role earn between $48.32 and $66.59 per hour, depending on experience, location, and employer.

What is a Remote Python Startup?

A Remote Python Startup is a company or organization that is in its early stages of development and primarily operates remotely, with its team members working from different locations. The startup's core products or services are typically built using the Python programming language, which is known for its versatility and ease of use in web development, data science, automation, and more. Working at a remote Python startup often requires strong collaboration skills, self-motivation, and proficiency in Python and related technologies. Team members typically communicate through online tools and platforms to manage projects, build products, and solve problems together.

What are the key skills and qualifications needed to thrive as a Remote Python Developer at a startup, and why are they important?

To thrive as a Remote Python Developer at a startup, you need strong proficiency in Python programming, problem-solving abilities, and experience with web frameworks or APIs, often supported by a degree in computer science or related field. Familiarity with tools like Git, Docker, cloud platforms (AWS, GCP), and continuous integration systems is typically required. Self-motivation, adaptability, and excellent written communication are crucial soft skills for collaborating within distributed, fast-paced startup teams. These skills ensure you can deliver effective solutions, adapt to evolving priorities, and contribute positively to the startup's growth and remote culture.

What is the difference between Remote Python Startup vs Remote Data Analyst?

AspectRemote Python StartupRemote Data Analyst
Required CredentialsPython programming skills, possibly some web frameworks, basic data handlingStatistical knowledge, data analysis tools, SQL, possibly some programming
Work EnvironmentTech startups, flexible remote settings, collaborative teamsBusiness or tech companies, remote or hybrid, focus on data insights
Industry UsageSoftware development, startups, tech industryFinance, marketing, healthcare, and other data-driven sectors

Remote Python Startup roles focus on software development using Python, often in startup environments, while Remote Data Analyst positions emphasize analyzing data to inform business decisions. Both roles require technical skills but differ in focus and industry application.

How does working at a remote Python startup typically differ from larger, more established companies in terms of daily responsibilities and team collaboration?

At a remote Python startup, you can expect to wear multiple hats, often taking on responsibilities beyond strict coding, such as contributing to product decisions or helping shape development processes. Daily tasks are usually fast-paced and can shift rapidly as priorities change, requiring adaptability and strong self-motivation. Team collaboration often relies on digital tools like Slack, GitHub, and video meetings, fostering a culture of frequent communication and autonomy. This environment provides unique opportunities for rapid skill growth, direct impact on the company's success, and close collaboration with founders and cross-functional teams.
More about Remote Python Startup jobs
What cities are hiring for Remote Python Startup jobs? Cities with the most Remote Python Startup job openings:
What are the most commonly searched types of Python Startup jobs? The most popular types of Python Startup jobs are:
What states have the most Remote Python Startup jobs? States with the most job openings for Remote Python Startup jobs include:
What job categories do people searching Remote Python Startup jobs look for? The top searched job categories for Remote Python Startup jobs are:
Remote Python Startup jobs near you
Infographic showing various Remote Python Startup job openings in the United States as of June 2026, with employment types broken down into 52% Full Time, 47% Part Time, and 1% Contract. Highlights an 81% Physical, 2% Hybrid, and 17% Remote job distribution, with an average salary of $121,932 per year, or $58.6 per hour.

Senior Full Stack Software Engineer

twenty80.io

Boston, MA • On-site, Remote

$160K - $210K/yr

Full-time

Medical, Dental, Vision, PTO

Posted 25 days ago

Job description

About the Role

A growing technology startup is hiring a Senior Full Stack Software Engineer to help build and scale its core product. This engineer will work across the frontend and backend, contributing directly to customer-facing features as well as internal systems. The role offers a high level of ownership and influence over technical decisions in a fast-paced environment.

This position is well-suited for an engineer who enjoys working closely with product and design, shipping quickly, and improving systems over time.

What You’ll Do

  • Build and maintain full stack web applications used by customers and internal teams

  • Develop scalable backend services and APIs to support product features

  • Implement modern, responsive frontend interfaces with a focus on usability and performance

  • Collaborate with product managers and designers to define requirements and deliver solutions

  • Contribute to architectural decisions and technical roadmap planning

  • Write high-quality, well-tested code and participate in code reviews

  • Help improve engineering processes, tooling, and system reliability

  • Mentor junior engineers and contribute to a strong engineering culture

Tech Environment

The engineering team works with a modern startup stack, including:

  • Frontend: React, TypeScript, Next.js

  • Backend: Node.js (Express or NestJS) and/or Python (Django or FastAPI)

  • Databases: PostgreSQL, Redis

  • Cloud & Infrastructure: AWS or GCP, Docker, CI/CD

  • APIs: REST and GraphQL

  • Tools: Git, GitHub, modern monitoring and logging tools

What We’re Looking For

  • 5+ years of professional software engineering experience

  • Strong full stack experience with modern JavaScript/TypeScript

  • Proven experience building and maintaining backend services and APIs

  • Solid understanding of relational databases and data modeling

  • Experience deploying and operating applications in cloud environments

  • Ability to work independently and take ownership of projects

  • Prior experience in a startup or fast-moving product team is a plus

Compensation & Benefits

  • Base Salary: $160,000 – $210,000 (San Francisco senior-level range)

  • Equity: Competitive equity package

  • Benefits: Medical, dental, vision coverage; flexible PTO; standard startup benefits

  • Work Model: Hybrid or remote-friendly depending on location and team needs

Equal Opportunity

This role is with an equal opportunity employer. Qualified applicants will be considered without regard to race, color, religion, gender, sexual orientation, gender identity, age, disability, or veteran status.