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Remote Prompt Engineering Jobs in Boston, MA (NOW HIRING)

AI Engineer

Beverly, MA · On-site +1

$119K - $179K/yr

This is a hybrid in office / remote role. Job Summary We are seeking a highly skilled Artificial ... Enhance AI agent effectiveness through techniques such as prompt engineering, retrieval-augmented ...

Deep AI expertise, especially in prompt engineering, orchestration layers, or verticalized AI ... In addition, we also have remote opportunities in China and India. More Than Just a Job Everyone ...

Agent Product Manager

Boston, MA · On-site +1

$150K - $190K/yr

Familiarity with prompt engineering or agent-based AI systems * Background in product design ... Flexible work environment with remote work options * Collaborative and innovative company culture

AI Product Manager

Boston, MA · On-site +1

$150K - $200K/yr

Familiarity with prompt engineering or agent-based AI systems * Background in product design ... Flexible work environment with remote work options * Collaborative and innovative company culture

Senior Applied Data Scientist

Boston, MA · On-site +1

$150K - $180K/yr

Experience using third-party generative AI systems, including prompt engineering and fine-tuning ... Remote -- United States Employment type: Full-time About 3Play Media 3Play Media is a technology ...

Advisory Solution Consultant - East

Boston, MA · On-site +1

$179K - $295K/yr

Working knowledge of GenAI , LLMs , Prompt Engineering , or Conversational UX design. * Strong ... Work personas (flexible, remote, or required in office) are categories that are assigned to ...

Backend Engineer/FullStack

Cambridge, MA · On-site +1

$140K - $220K/yr

You'll work at the intersection of engineering and applied ML, building systems that process real ... Exposure to LLM-driven systems (prompt management, caching, streaming) * Experience with Docker;

Data Engineer with AI - Remote

Boston, MA · On-site +1

$124K - $149K/yr

You'll design robust ETL/ELT, enable feature engineering for ML/LLM use cases , and drive best ... prompt/response logging). * Cloud proficiency on AWS/Azure/GCP (object storage, IAM, networking)

Senior Project Engineer

Weston, MA · On-site +1

$75K - $182K/yr

Provide accurate and prompt responses to RFIs and submittal reviews. * Support continuous ... Bachelor's degree in engineering (mechanical, civil, chemical, environmental, Geotech) * 7-12 years ...

Principal Software Engineer

Boston, MA · On-site +1

$151K - $249K/yr

Engineering Excellence: Drive AI integration within the software development lifecycle (SDLC ... For positions with Remote-US locations, the actual salary range for the position may differ based ...

Senior Machine Learning Engineer

Boston, MA · On-site +1

$174K - $287K/yr

Give thoughtful and prompt code reviews * Mentor and guide other engineers and foster a culture of ... For positions with Remote-US locations, the actual salary range for the position may differ based ...

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Remote Prompt Engineering information

See Boston, MA salary details

$18

$35

$51

How much do remote prompt engineering jobs pay per hour?

As of Jun 15, 2026, the average hourly pay for remote prompt engineering in Boston, MA is $35.91, according to ZipRecruiter salary data. Most workers in this role earn between $28.75 and $41.54 per hour, depending on experience, location, and employer.

How can I make 2000 a week working from home?

Remote prompt engineering is a freelance or contract role that can generate significant income if you have strong skills in AI, natural language processing, and prompt design. Earning $2000 weekly typically requires multiple clients, high-quality work, and efficient time management, often involving project-based tasks or retainer agreements. Building a portfolio and gaining experience with tools like GPT models can help increase earning potential.

What engineers make $500,000?

Senior engineers in specialized fields such as software engineering, data engineering, or machine learning engineering can earn $500,000 or more annually, especially with extensive experience, advanced skills, and in high-demand industries. Compensation often includes base salary, bonuses, and stock options, particularly at large tech companies or startups with significant funding.

What is the difference between Remote Prompt Engineering vs Remote Data Annotation Specialist?

AspectRemote Prompt EngineeringRemote Data Annotation Specialist
Required CredentialsBasic understanding of AI, NLP, and scripting skillsAttention to detail, familiarity with annotation tools, no formal certifications required
Work EnvironmentCollaborative with AI/ML teams, remote setupIndependent annotation tasks, remote or on-site
Industry UsageAI development, NLP projects, machine learningData labeling for AI training datasets
Search & Comparison IntentUnderstanding roles in AI development, job requirementsData labeling jobs, annotation tasks, related roles

Remote Prompt Engineering involves designing and refining prompts for AI models, requiring some technical skills and collaboration with AI teams. In contrast, Remote Data Annotation Specialists focus on labeling data to train AI systems, emphasizing attention to detail. Both roles are essential in AI development but differ in skills and daily tasks.

What are some common challenges faced by remote prompt engineers, and how can they be addressed?

Remote prompt engineers often face challenges related to communication and collaboration, especially when working across time zones and with interdisciplinary teams. Staying updated on rapidly evolving AI technologies and understanding nuanced user requirements can also be demanding. To address these, prompt engineers can leverage collaborative tools, maintain clear documentation, and participate in regular team syncs. Building a habit of continuous learning and engaging in knowledge-sharing sessions helps keep skills relevant and fosters a sense of connection despite remote work.

What are the key skills and qualifications needed to thrive as a Remote Prompt Engineer, and why are they important?

To thrive as a Remote Prompt Engineer, you need a strong background in natural language processing, programming (often Python), and an understanding of AI/ML concepts, typically supported by a relevant degree or industry experience. Familiarity with large language models (like OpenAI's GPT), prompt optimization tools, and version control systems such as Git is common. Creativity, problem-solving, and strong written communication are vital soft skills for designing effective prompts and collaborating remotely. These skills ensure the development of high-performing AI solutions and seamless teamwork in distributed environments.

Are prompt engineers still in demand?

Prompt engineering is a growing field as organizations seek to optimize AI language models for various applications. Demand for prompt engineers is increasing, especially for roles involving natural language processing, AI model tuning, and familiarity with tools like GPT and other large language models.

How to make $1000 a week remote?

Remote prompt engineering involves creating and refining prompts for AI models, and experienced professionals can earn around $20 to $50 per hour. To make $1000 weekly, one would need to work approximately 20 to 50 hours at this rate, often requiring strong language skills, familiarity with AI tools, and consistent project availability. Building a portfolio and gaining certifications can help increase earning potential in this field.

What is remote prompt engineering?

Remote prompt engineering is the practice of designing and refining prompts for AI language models, such as ChatGPT, while working from a remote location. Prompt engineers craft instructions or questions to optimize the model’s responses for specific tasks or applications. This role typically involves understanding both the capabilities and limitations of AI systems, as well as the needs of end users or clients. Remote prompt engineers collaborate online with teams and may work for tech companies, research organizations, or as independent contractors.
What are the most commonly searched types of Prompt Engineering jobs in Boston, MA? The most popular types of Prompt Engineering jobs in Boston, MA are:
What are popular job titles related to Remote Prompt Engineering jobs in Boston, MA? For Remote Prompt Engineering jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Remote Prompt Engineering jobs in Boston, MA look for? The top searched job categories for Remote Prompt Engineering jobs in Boston, MA are:
What cities near Boston, MA are hiring for Remote Prompt Engineering jobs? Cities near Boston, MA with the most Remote Prompt Engineering job openings:
Infographic showing various Remote Prompt Engineering job openings in Boston, MA as of June 2026, with employment types broken down into 94% Full Time, and 6% Part Time. Highlights an 35% In-person, and 65% Remote job distribution, with an average salary of $74,701 per year, or $35.9 per hour.
Principal Software Engineer

Principal Software Engineer

eClinical Solutions

Mansfield, MA • On-site, Remote

$142K - $191K/yr

Other

Posted 8 days ago


Job description

About eClinical Solutions

eClinical Solutions is transforming clinical development with elluminate, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle-accelerating innovation that ultimately improves patient outcomes.

Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.

You will make an impact: 

As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform-while influencing architecture, engineering standards, and technical direction.

This role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities-including AI-assisted and agentic workflows-into production-grade systems.

Your day to day: 

  • Design, develop, test, and deploy scalable, secure, and highly interactive web applications
  • Own and evolve core platform modules, from concept through release and support
  • Influence application and system architecture with a focus on performance, reliability, security, and maintainability
  • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions
  • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
  • Provide technical mentorship and guidance to other engineers on the team
  • Diagnoses and resolves complex production issues across distributed systems
  • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
  • Contribute to technical documentation including design specs, acceptance criteria, and release notes

AI & Modern Engineering Focus

We're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:

  • Integrating LLMs and AI services into .NET- and Python-based systems
  • Designing and implementing AI-assisted workflows, copilots, or intelligent automation features
  • Working with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)
  • Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
  • Collaborating with data and platform teams to operationalize AI-not just prototype it

Deep ML expertise is not required-we're looking for strong engineers who understand how to apply AI capabilities in real products.

Take the first step toward your dream career.  Here is what we are looking for in this role. 

 Qualifications:

  • Bachelor's or Master's degree in Computer Science or equivalent practical experience 
  • 10+ years in software design and development using the Microsoft technology stack preferred 
  • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)
  • Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)
  • Solid understanding of software design principles, patterns, and best practices
  • Experience across the full Software Development Lifecycle (Agile preferred)
  • Proven ability to work independently while collaborating effectively in a fast-paced environment
  • Excellent communication, documentation, and technical leadership skills

AI & Platform Experience

  • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
  • Experience using Python and/or .NET alongside AI/LLM workflows
  • Familiarity with agent-based or workflow-driven AI architectures is a strong plus
  • Understanding of secure and responsible AI usage in enterprise systems

Nice to Have

  • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
  • Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
  • Secure development experience, including awareness of common vulnerabilities and mitigations
  • Experience with clinical trial data, life sciences, or regulated SaaS environments
  • Experience building data visualizations or analytics-driven user experiences

Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!

eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/

eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!

We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.

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