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Process Chemist Jobs (NOW HIRING)

ARL

Data Processing Chemist

Oklahoma City, OK · On-site

$23 - $26/hr

Process detailed Chromatography data for QMS compliance, reporting and correcting any errors or ... Associate Degree in Chemistry or related Science Field- or equivalent Diploma with 1 year of ...

ChampionX

Senior Chemist/ Engineer

Sugar Land, TX

Collaborate with process chemists and engineering teams to translate lab-scale chemistry into scalable and reproducible processes * Assess process engineering requirements for incoming blend and ...

ChampionX

Senior Chemist/ Engineer

Sugar Land, TX · On-site

Collaborate with process chemists and engineering teams to translate lab-scale chemistry into scalable and reproducible processes * Assess process engineering requirements for incoming blend and ...

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How much do process chemist jobs pay per year?

As of Aug 18, 2026, the average yearly pay for process chemist in the United States is $84,782.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,000.00 and $105,000.00 per year, depending on experience, location, and employer.

What is a process chemist?

Process chemists are specialized scientists who develop, scale up, and optimize chemical processes for manufacturing products, such as pharmaceuticals, agrochemicals, and specialty chemicals. They work to ensure that these processes are efficient, cost-effective, and safe for large-scale production. Process chemists collaborate closely with chemical engineers and production teams to transition laboratory methods to industrial-scale operations, while also addressing environmental and regulatory requirements.

What are the key skills and qualifications needed to thrive as a process chemist, and why are they important?

To thrive as a Process Chemist, you need a solid background in chemistry or chemical engineering, typically with a bachelor's or master's degree in a related field. Proficiency with laboratory instruments, process simulation software, and familiarity with safety and regulatory standards are commonly required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help distinguish successful candidates. These competencies ensure safe, efficient process development and scale-up, which are critical for producing high-quality chemical products.

What are some common challenges faced by process chemists when transferring a chemical process from the lab to full-scale manufacturing?

Process Chemists often encounter challenges when scaling up a reaction from the laboratory to production scale, such as maintaining product quality, ensuring safety, and optimizing yields. Variables like mixing, temperature control, and raw material variability can behave differently at larger volumes, requiring careful adjustment and troubleshooting. Close collaboration with chemical engineers, safety specialists, and production staff is essential to address these issues and ensure a smooth, efficient, and compliant manufacturing process.

What is the difference between Process Chemist vs Analytical Chemist?

AspectProcess ChemistAnalytical Chemist
CredentialsBachelor's or Master's in Chemistry or Chemical EngineeringBachelor's or Master's in Chemistry or related field
Work EnvironmentManufacturing plants, production facilitiesLaboratories, research settings
Industry UsagePharmaceuticals, chemicals, manufacturingPharmaceuticals, environmental testing, quality control
Job FocusOptimizing production processes, scale-up, process improvementsAnalyzing samples, testing, method development

While both roles require a chemistry background, a Process Chemist focuses on manufacturing processes and scaling production, whereas an Analytical Chemist specializes in testing and analyzing samples to ensure quality and compliance. The roles often overlap in industries like pharmaceuticals and chemicals but differ in daily tasks and focus areas.

How much do process chemists make in the US?

Process chemists in the US typically earn a median annual salary of around $70,000 to $90,000, with experienced professionals and those working in specialized industries earning higher. Salaries can vary based on education, experience, location, and the complexity of processes they manage.
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What cities are hiring for Process Chemist jobs?

Cities with the most Process Chemist job openings:

What states have the most Process Chemist jobs?

States with the most job openings for Process Chemist jobs include:

What are popular job titles related to Process Chemist jobs?

For Process Chemist jobs, the most frequently searched job titles are:

Process Chemist jobs near you
Infographic showing various Process Chemist job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 16% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $84,782 per year, or $40.8 per hour.

Senior Scientist / Principal Scientist - Process Chemistry

Treeline Biosciences

San Diego, CA • On-site

Full-time

This job post has expired today. Applications are no longer accepted.

Job description

Treeline Biosciences, a clinical-stage biotechnology company advancing precision medicines, is seeking an experienced small molecule process chemist to drive the development, scale-up, and commercial readiness of our small molecule, clinical-stage portfolio. This role centers around close collaboration with the medicinal chemistry team within the discovery portfolio. Additionally, the role is critical to ensuring clinical supply and commercial readiness for identified programs and ensuring that drug substance manufacturing processes meet quality, regulatory, safety, scalability, and scalability expectations.
About the Position
Senior Scientist / Principal Scientist - Process Chemistry (Discovery Process Research)
Position Overview
We are seeking an experienced synthetic chemist to join our Process Chemistry (Discovery Process Research) team supporting drug discovery programs. This role focuses on route invention, reaction development, and scalable synthesis of key intermediates and drug candidates.
The scientist will lead from the bench within our project-based research and development organization, designing and executing synthetic strategies that enable discovery programs. The successful candidate will collaborate with cross-functional teams, including Medicinal Chemistry, DMPK, Toxicology, Drug Product, and Analytical Sciences to develop practical routes that support SAR exploration and deliver material for biological and early toxicology studies. The role emphasizes modern synthetic methodologies, efficient route design, and early scalability assessment.
Scientific Impact
  • Enable drug discovery through innovative synthetic strategy. Develop creative and efficient routes that accelerate SAR exploration, enable rapid evaluation of new chemical matter, and deliver material for early toxicology studies.
  • Solve complex synthetic challenges. Apply modern synthetic methodologies to access structurally complex molecules and support emerging therapeutic modalities.
  • Translate discovery chemistry into scalable processes. Design practical routes that support both rapid compound synthesis and early-stage scale-up.
  • Advance cross-disciplinary drug discovery. Partner closely with discovery scientists to translate synthetic innovation into therapeutic progress.

Responsibilities
  • Collaborate with medicinal chemistry partners to support candidate selection and developability assessments. Advise and assist with sourcing scaffolds and intermediates as appropriate.
  • Design and execute route scouting and synthetic strategies for drug candidates and key intermediates.
  • Design and optimize chemical transformations and scalable synthetic routes to enable efficient and robust processes for discovery and early development programs.
  • Enable rapid compound synthesis and methodologies to support SAR campaigns and discovery timelines.
  • Apply modern synthetic technologies to address complex synthetic challenges.
  • Support multi-gram to kilogram-scale synthesis for biological and toxicology studies.
  • Manage external partners and cultivate strong, collaborative relationships to support program objectives.
  • Contribute to early CMC understanding, including impurity identification and process considerations.
  • Communicate results through technical reports, documentation, and presentations.
  • May be involved with preparations for the first GMP synthesis of a clincial candidate for Phase 1 trials.
  • Ability to travel up to 10% to support program needs, including on-site support at manufacturing plants and partner collaboration.

Qualifications
  • Ph.D. in Organic Chemistry or related discipline with 3-8+ years of relevant industry or postdoctoral experience; M.S. with 6-10+ years of industry experience also considered.
  • Strong expertise in synthetic organic chemistry, reaction development, and route design.
  • Experience with complex molecule synthesis and route optimization.
  • Familiarity with scale-up considerations and impurity control in chemical processes.
  • Ability to work effectively within cross-functional discovery teams.
  • Experience working with and managing external CDMO partners.
  • Strong written and verbal communication skills.
  • Strong project leadership skills with the ability to manage complex timelines, multiple stakeholders, and evolving program priorities.
  • Strong communication and collaboration skills with a proven ability to work cross-functionally in a fast-paced, science-driven environment.
  • High level of personal integrity, commitment to excellence and to our patients

Desired Experience
  • Experience with modern synthetic methodologies and technologies (e.g., catalysis, flow chemistry, photochemistry, high-throughput experimentation, as well as other techniques).
  • Experience enabling synthesis of structurally complex drug candidates or emerging modalities.
  • Demonstrated creative problem solving in synthetic chemistry.

This position is classified as exempt. The anticipated annual base salary range for candidates who will work in San Diego is $166,380 to $189,533. The final base salary offered to the successful candidate will be dependent upon several factors that may include but are not limited to the type and length of experience within the job, and other factors. Treeline Biosciences is a multi-state employer, and this salary range may not reflect positions that work in other cities or states.
Recruitment fraud statement
Please be aware of recruitment fraud and related job scams, where scammers present themselves as recruiters but are seeking to steal money or personal information. Keep the following in mind to protect yourself:
  • Treeline Biosciences will never ask for money from you as part of our recruitment process. Do not provide bank details or pay somebody for the promise of a job at Treeline.
  • We do not conduct interviews through RingCentral, Skype or Telegram.
  • Our job openings are first posted to treeline.bio/careers. If you locate a listing for a Treeline job on another site, please ensure it is also posted on our careers website.
  • You can find more information about job scams at consumer.ftc.gov/articles/job-scams.
  • To report job scams, head to ReportFraud.ftc.gov.

Notice to Search Firms/Third-Party Recruitment Agencies (Recruiters)
The Human Resources team manages the recruitment and employment process for Treeline Biosciences. To protect the interests of all parties involved, Treeline Biosciences will only accept resumes from a recruiter if an executed search agreement directed to the particular position or positions is in place at the start of the recruitment effort. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.

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