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Process Chemist Jobs in Madison, WI (NOW HIRING)

Chemist

Madison, WI

$24 - $26/hr

Laboratory Chemist We are seeking a Laboratory Chemist to join a growing bioanalytical laboratory ... Prepare and process biological samples, including blood, urine, and plasma. * Perform laboratory ...

As an Associate Analytical Chemist, you will be part of the Laboratory Support team supporting food ... Receive and process samples, including labeling and storage management * Work with dry ice and ...

Associate ChemistLaunch Your Career in Analytical Chemistry Join a leading food and dietary ... We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing ...

The role of the Senior R&D Chemist plays a critical part in radiochemical process development and ensuring regulatory and safety compliance. The base salary range for this position is $75,000 - $120 ...

Senior R&D Chemist

Janesville, WI ยท On-site

$75K - $120K/yr

The role of the Senior R&D Chemist plays a critical part in radiochemical process development and ensuring regulatory and safety compliance. The base salary range for this position is $75,000 - $120 ...

Senior R&D Chemist

Janesville, WI ยท On-site

$75K - $120K/yr

The role of the Senior R&D Chemist plays a critical part in radiochemical process development and ensuring regulatory and safety compliance. The base salary range for this position is $75,000 - $120 ...

S. chemistry, biochemistry, biology or related life science field (ask if candidate has taken ... We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing ...

Laboratory Chemist We are seeking a Laboratory Chemist to join a growing bioanalytical laboratory ... Prepare and process biological samples, including blood, urine, and plasma. * Perform laboratory ...

R&D Chemist

Janesville, WI ยท On-site

$60K - $65K/yr

Description SHINE Technologies is seeking an Entry Level R&D Chemist to develop and implement activities and experiments related to radiochemical separation techniques and processes to support the ...

New

R&D Chemist

Janesville, WI ยท On-site

$60K - $65K/yr

SHINE Technologies is seeking an Entry Level R&D Chemist to develop and implement activities and experiments related to radiochemical separation techniques and processes to support the ...

Posted today

QC Laboratory ChemistAbout the Role Launch your chemistry career in a hands-on laboratory ... We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing ...

Associate Analytical Chemist

Madison, WI ยท On-site

$24.50 - $32.25/hr

Eurofins Food Chemistry Madison is growing and we're looking for amazing team members to join us ... As part of any recruitment process, the company collects and processes personal data relating to ...

Associate Analytical Chemist

Madison, WI ยท On-site

$24.50 - $32.25/hr

Eurofins Food Chemistry Madison is growing and we're looking for amazing team members to join us ... As part of any recruitment process, the company collects and processes personal data relating to ...

Associate Analytical Chemist

Madison, WI ยท On-site

$24.50 - $32.25/hr

Eurofins Food Chemistry Madison is growing and we're looking for amazing team members to join us ... As part of any recruitment process, the company collects and processes personal data relating to ...

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Showing results 1-20

Process Chemist information

See Madison, WI salary details

$41.3K

$85.4K

$132K

How much do process chemist jobs pay per year?

As of Aug 12, 2026, the average yearly pay for process chemist in Madison, WI is $85,429.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,400.00 and $105,800.00 per year, depending on experience, location, and employer.

What is a process chemist?

Process chemists are specialized scientists who develop, scale up, and optimize chemical processes for manufacturing products, such as pharmaceuticals, agrochemicals, and specialty chemicals. They work to ensure that these processes are efficient, cost-effective, and safe for large-scale production. Process chemists collaborate closely with chemical engineers and production teams to transition laboratory methods to industrial-scale operations, while also addressing environmental and regulatory requirements.

What is the difference between Process Chemist vs Analytical Chemist?

AspectProcess ChemistAnalytical Chemist
CredentialsBachelor's or Master's in Chemistry or Chemical EngineeringBachelor's or Master's in Chemistry or related field
Work EnvironmentManufacturing plants, production facilitiesLaboratories, research settings
Industry UsagePharmaceuticals, chemicals, manufacturingPharmaceuticals, environmental testing, quality control
Job FocusOptimizing production processes, scale-up, process improvementsAnalyzing samples, testing, method development

While both roles require a chemistry background, a Process Chemist focuses on manufacturing processes and scaling production, whereas an Analytical Chemist specializes in testing and analyzing samples to ensure quality and compliance. The roles often overlap in industries like pharmaceuticals and chemicals but differ in daily tasks and focus areas.

What are the key skills and qualifications needed to thrive as a process chemist, and why are they important?

To thrive as a Process Chemist, you need a solid background in chemistry or chemical engineering, typically with a bachelor's or master's degree in a related field. Proficiency with laboratory instruments, process simulation software, and familiarity with safety and regulatory standards are commonly required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills help distinguish successful candidates. These competencies ensure safe, efficient process development and scale-up, which are critical for producing high-quality chemical products.

How much do process chemists make in the US?

Process chemists in the US typically earn a median annual salary of around $70,000 to $90,000, with experienced professionals and those working in specialized industries earning higher. Salaries can vary based on education, experience, location, and the complexity of processes they manage.

What are some common challenges faced by process chemists when transferring a chemical process from the lab to full-scale manufacturing?

Process Chemists often encounter challenges when scaling up a reaction from the laboratory to production scale, such as maintaining product quality, ensuring safety, and optimizing yields. Variables like mixing, temperature control, and raw material variability can behave differently at larger volumes, requiring careful adjustment and troubleshooting. Close collaboration with chemical engineers, safety specialists, and production staff is essential to address these issues and ensure a smooth, efficient, and compliant manufacturing process.
Infographic showing various Process Chemist job openings in Madison, WI as of August 2026, with employment types broken down into 1% As Needed, 72% Full Time, 23% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $85,429 per year, or $41.1 per hour.

Scientist III, Process Chemistry (Antibody-siRNA Conjugates)

Arrowhead Pharmaceuticals

Madison, WI โ€ข On-site

$110K - $125K/yr

Full-time

Re-posted 16 days ago


Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead Pharmaceuticals is seeking a motivated Scientist III to join our Process Chemistry team, focused on the development and scale-up of conjugated RNAi therapeutics. This role centers on process development for antibody-siRNA conjugates (AOCs/ARCs), a key expansion of Arrowhead's TRiM platform into targeted extrahepatic delivery. The successful candidate will span the full development continuum - taking discovery-stage conjugation protocols, optimizing them for robustness and reproducibility, and developing them into GMP, kilogram-scale manufacturing processes. This is a hands-on role at the bench combined with oversight of external CRO/CDMO partners.
Responsibilities
  • Optimize discovery-stage conjugation protocols for antibody-siRNA conjugates, improving yield, reproducibility, and product quality to enable scale-up.
  • Develop GMP-ready, kilogram-scale conjugation processes, including site-specific and stochastic conjugation strategies, linker chemistry, and payload attachment.
  • Work hands-on in the laboratory to design, execute, and optimize conjugation reactions, purification (chromatography, TFF/UF-DF), and analytical control strategies.
  • Oversee and direct CROs/CDMOs executing process development and manufacturing activities, including setting technical direction, reviewing data, and ensuring timelines and quality standards are met.
  • Characterize conjugates for DAR/siRNA-to-antibody ratio, aggregation, charge heterogeneity, and stability using relevant analytical methods (e.g., HIC, SEC, IEX, LC-MS, AEX).
  • Lead technology transfer to internal and external manufacturing partners, authoring process descriptions, batch records, and development reports.
  • Troubleshoot process and analytical challenges; design experiments to define process parameters, ranges, and robustness for kilogram-scale operation.
  • Collaborate cross-functionally with discovery chemistry, linker/conjugation chemistry, analytical development, and CMC teams

Requirements
  • PhD in Organic Chemistry, Bioconjugate Chemistry, Chemical Engineering, or a related field; or a Bachelor's/Master's degree with commensurate hands-on industry experience.
  • Demonstrated hands-on experience in siRNA conjugation development is required.
  • Working knowledge of oligonucleotide and/or antibody chemistry, linker design, and bioconjugation methods.
  • Familiarity with purification and analytical characterization of conjugates.
  • Strong problem-solving, documentation, and communication skills.

Preferred
  • Experience with antibody-oligonucleotide conjugates (AOCs) or antibody-drug conjugates (ADCs).
  • Experience developing and scaling processes to GMP/kilogram scale and managing CRO/CDMO relationships.
  • Knowledge of site-specific conjugation technologies (e.g., engineered cysteines, enzymatic/click chemistry).
  • Experience with tech transfer and CMC/GMP environments.

Wisconsin pay range
$110,000-$125,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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