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Prn Rn Jobs in Temecula, CA (NOW HIRING)

CA Registered Nurse License - Required * American Heart Association BLS Provider - Required ... Assess patient needs for PRN medications and respond accordingly. * Document assessments. Evaluate ...

Acute Dialysis RN

Menifee, CA · On-site

$2.0K - $2.5K/wk

... Registered Nurse License - Required 4. American Heart Association BLS Provider - Required 5. ... Assess patient needs for PRN medications and respond accordingly. 4. Document assessments. Evaluate ...

LVN - PRN

Temecula, CA · On-site

$30 - $40/hr

This position is primarily responsible for providing planned and highly skilled nursing care under the supervision of a RN. This position is also responsible for providing continuous patient ...

LVN - PRN

Temecula, CA · On-site

$30 - $40/hr

This position is primarily responsible for providing planned and highly skilled nursing care under the supervision of a RN. This position is also responsible for providing continuous patient ...

LVN - PRN

Temecula, CA · On-site

$30 - $40/hr

This position is primarily responsible for providing planned and highly skilled nursing care under the supervision of a RN. This position is also responsible for providing continuous patient ...

Valid state Registered Nurse license. * Valid BLS certification Experience * Two years of nursing experience in a hospital. * 1 to 2 years supervisory/leadership experience

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Prn Rn information

See Temecula, CA salary details

$19

$36

$53

How much do prn rn jobs pay per hour?

As of Aug 26, 2026, the average hourly pay for prn rn in Temecula, CA is $36.24, according to ZipRecruiter salary data. Most workers in this role earn between $28.89 and $41.78 per hour, depending on experience, location, and employer.

What is a PRN RN?

PRN RNs are registered nurses who work 'pro re nata,' a Latin phrase meaning 'as needed.' These nurses do not have a set schedule but instead fill in shifts when there are staffing shortages or increased patient needs. PRN RNs can work in various healthcare settings, including hospitals, clinics, and nursing homes. This job offers flexibility, but hours and benefits may vary depending on the employer and the frequency of shifts worked.

What are the key skills and qualifications needed to thrive as a PRN RN, and why are they important?

To thrive as a PRN RN, you need a nursing degree, an active RN license, and a solid understanding of clinical procedures and patient care. Familiarity with electronic health records (EHRs), medication administration systems, and common clinical equipment is crucial. Excellent adaptability, communication, and time-management skills help PRN RNs adjust quickly to new settings and work effectively with different teams. These competencies ensure safe, high-quality patient care even in variable or fast-changing environments.

What are some common challenges faced by PRN RNs, and how can they effectively adapt to different units or teams?

PRN (pro re nata, or as-needed) RNs often face the challenge of quickly adapting to various units, patient populations, and workflows since they may float between different departments based on staffing needs. Effective communication, flexibility, and a strong foundational nursing knowledge are crucial for success in this role. Building rapport with permanent staff and familiarizing yourself with each unit’s protocols during orientation can ease transitions and improve patient care. Being proactive in asking questions and seeking clarification helps ensure safe and efficient practice while working in diverse environments.

What is the difference between Prn Rn vs Full-Time Rn?

FeaturePrn RnFull-Time Rn
Work ScheduleAs needed, flexible shiftsScheduled, regular shifts
CertificationsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentHospitals, clinics, home careHospitals, clinics, long-term care
Employer UsageHospitals, staffing agenciesHospitals, healthcare facilities

Prn Rn nurses work on an as-needed basis with flexible hours, ideal for those seeking part-time or supplemental work. Full-Time Rn nurses have scheduled shifts and consistent hours, providing stability and benefits. Both roles require an RN license and are common in similar healthcare settings, but differ mainly in scheduling and employment structure.

Is working PRN registered nurse worth it?

Working as a PRN registered nurse offers flexibility in scheduling and the ability to choose shifts based on availability, which can improve work-life balance. However, PRN positions often have variable hours and may lack benefits like health insurance or paid time off, so their value depends on individual priorities and financial needs.

What does a PRN registered nurse do?

A PRN registered nurse provides healthcare services on an as-needed basis, often working flexible or temporary shifts in hospitals, clinics, or other medical settings. They perform patient assessments, administer medications, and assist with procedures, requiring active RN licensure and relevant clinical skills. PRN nurses typically do not have a fixed schedule and may work multiple facilities or units based on staffing needs.

What are the most commonly searched types of Prn Rn jobs in Temecula, CA?

The most popular types of Prn Rn jobs in Temecula, CA are:

What cities near Temecula, CA are hiring for Prn Rn jobs?

Cities near Temecula, CA with the most Prn Rn job openings:

Infographic showing various Prn Rn job openings in Temecula, CA as of August 2026, with employment types broken down into 3% As Needed, 55% Full Time, 15% Part Time, and 27% Contract. Highlights an 98% Physical, and 2% Remote job distribution, with an average salary of $75,372 per year, or $36.2 per hour.

PRN/Per-Diem Research Nurse (LVN)

Escondido, CA • On-site

Headlands Research
Scientific Research and Development Services • 51 - 200 employees

$35 - $40/hr

Per diem

Re-posted 23 days ago


Job description

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.
OVERVIEW / POSITION DESCRIPTION
The AMCR Institute is a cutting-edge research institute specializing in the execution of Phase I-IV diabetes device and biopharmaceutical trials. Eligible subjects are offered the latest treatment options carried out under the strict guidelines from the Food and Drug Administration (FDA). Research subjects (Volunteers) become the most critical link in a chain of research and testing to develop breakthrough treatments for a broad range of health problems including Type 1 and Type 2 Diabetes. At all times the safety and confidentiality are guarded with the utmost concern.
As a member of AMCR Institute, you will contribute to the development of novel therapies and supportive technology for people with diabetes and be part of the discovery of new treatments.
The Clinical Research Nurse (RN) is a licensed clinical professional working with and under the direction of the Principal Investigator, Assistant Director, Lead Research Nurse, and in close conjunction with the Clinical Project Manager on early or late phase clinical trials related to the treatment of diabetes. The Clinical Research Nurse is an integral member of the clinical trial team and assumes responsibility and accountability for the direct research care of a group of research subjects during a designated time frame. The Clinical Research Nurse is responsible for assuring compliance with the Federal and State regulations relating to research and the study protocol requirements.
MATERIALS AND EQUIPMENT DIRECTLY USED
  1. Phlebotomy and IV supplies including infusion pumps
  2. Office equipment such as personal computer, printer and copier, telephone, fax
  3. Diabetes-related medical devices (e.g. glucometer, insulin delivery devices, etc.)

INTERRELATIONSHIPS
Physicians, Nurse Practitioners, Physician Assistants, Nurses, Research Staff, Research Subjects, and Clinical Office and Administrative Staff
DUTIES AND RESPONSIBILITIES
Research / Regulatory:
  1. Contributes to data collection by adhering to "Good Documentation Practices"
  2. Documents in detail the data obtained following AMCR Institute's Standard Operating Procedure (SOP).
  3. Competently recognizes signs and symptoms of Hypoglycemia, Hyperglycemia, and Ketosis and alerts the lead coordinator and clinician.
  4. Working knowledge of research protocol to understand the science behind the study.
  5. Assists research staff in specimen processing: spinning, pipetting, and analyzing using the YSI glucose instrument.
  6. Discharge research subject upon completion of in-clinic visit following the "Glycemic Discharge Protocol for AMCR Institute".

Clinical:
  1. Conducts a centered research subject assessment focusing on safety and venous access placement.
  2. Using aseptic technique, identifies the largest accessible vein and starts intravenous placement (IV) on adults and pediatric research subjects. Number of IV lines depending on the research design. May place two (2) IV lines on the same arm and/or another line on the opposite arm.
  3. Using aseptic technique, changes IV bags PRN and adjust infusion pumps flow rate.
  4. Employs strategies in maintaining subject's safety: monitoring heating pad temperature, awareness of blood glucose levels, phlebitis.
  5. Administers research drugs and/or medications as ordered by a clinician.
  6. Using aseptic technique, assists research staff in blood drawing using a 3-way stopcock method.
  7. Assists research staff with performing vital signs and EKG tracings.
  8. Provides the tools and necessary support to subjects in learning their diabetes management responsibilities in accordance with the protocol.
  9. Provides nursing support to staff regarding diabetes issues as needed.
  10. Organizes and prioritizes workload to effectively accomplish goals.

Communication
  1. Communicates clearly and effectively with clinicians, nursing and research staff, and research subjects.
  2. Check-in and report with the Lead Research Coordinator and/or RN at the start and end of each shift and provide a complete outgoing report.
  3. Sign / initial / and date all documents that were worked on during shift prior to leaving.

SCHEDULE
Shift availability varies depending upon the type and number of active research protocols being executed. Shift may range from 4 to 12 hours. Some flexibility may be possible depending upon the protocol. RNs are strongly encouraged to attend monthly meetings led by the Lead Research Nurse. These meetings may include protocol and skills training, updates, and other topics as needed.
California Pay Range
$35-$40 USD
Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver's license information, etc) via email or messenger tools, or for a financial deposit of any kind.
Headlands Research is an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, age, sex, national origin, disability status, genetic information, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
Need Assistance?
Headlands Research is committed to providing access and reasonable accommodation in its employment for individuals with disabilities. To request disability accommodation in the application process, contact recruiting@headlandsresearch.com for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.