1

Prn Rn Jobs in Lexington, SC (NOW HIRING)

PRN Healthcare is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

PRN Healthcare is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Stepdown * Discipline: RN * Start Date: 09/21 ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

PRN Healthcare is seeking a travel nurse RN Cardiac Stepdown for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Stepdown * Discipline: RN * Start Date: 09/14 ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

PRN Healthcare is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Med Surg / Telemetry * Discipline: RN * Start Date ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TotalMed RN is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TotalMed RN is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Columbia ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

PRN Healthcare is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Cardiac Cath Lab * Discipline: RN * Start Date: 09/28 ...

Travel MS/Telemetry RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TotalMed RN is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TotalMed RN is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

Travel MS/Tele RN

Columbia, SC · On-site

$1.6K - $2.2K/wk

TotalMed RN is seeking a travel nurse RN Long Term Acute Care Med Surg / Telemetry for a travel ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

TotalMed RN is seeking a travel nurse RN Cardiac Cath Lab for a travel nursing job in Columbia ... TotalMed specializes in recruiting and placing healthcare professionals in travel, PRN, and ...

Showing results 21-40

Prn Rn information

See Lexington, SC salary details

$16

$31

$46

How much do prn rn jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for prn rn in Lexington, SC is $31.22, according to ZipRecruiter salary data. Most workers in this role earn between $24.90 and $36.01 per hour, depending on experience, location, and employer.

What is a PRN RN?

PRN RNs are registered nurses who work 'pro re nata,' a Latin phrase meaning 'as needed.' These nurses do not have a set schedule but instead fill in shifts when there are staffing shortages or increased patient needs. PRN RNs can work in various healthcare settings, including hospitals, clinics, and nursing homes. This job offers flexibility, but hours and benefits may vary depending on the employer and the frequency of shifts worked.

What are the key skills and qualifications needed to thrive as a PRN RN, and why are they important?

To thrive as a PRN RN, you need a nursing degree, an active RN license, and a solid understanding of clinical procedures and patient care. Familiarity with electronic health records (EHRs), medication administration systems, and common clinical equipment is crucial. Excellent adaptability, communication, and time-management skills help PRN RNs adjust quickly to new settings and work effectively with different teams. These competencies ensure safe, high-quality patient care even in variable or fast-changing environments.

What are some common challenges faced by PRN RNs, and how can they effectively adapt to different units or teams?

PRN (pro re nata, or as-needed) RNs often face the challenge of quickly adapting to various units, patient populations, and workflows since they may float between different departments based on staffing needs. Effective communication, flexibility, and a strong foundational nursing knowledge are crucial for success in this role. Building rapport with permanent staff and familiarizing yourself with each unit’s protocols during orientation can ease transitions and improve patient care. Being proactive in asking questions and seeking clarification helps ensure safe and efficient practice while working in diverse environments.

What is the difference between Prn Rn vs Full-Time Rn?

FeaturePrn RnFull-Time Rn
Work ScheduleAs needed, flexible shiftsScheduled, regular shifts
CertificationsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentHospitals, clinics, home careHospitals, clinics, long-term care
Employer UsageHospitals, staffing agenciesHospitals, healthcare facilities

Prn Rn nurses work on an as-needed basis with flexible hours, ideal for those seeking part-time or supplemental work. Full-Time Rn nurses have scheduled shifts and consistent hours, providing stability and benefits. Both roles require an RN license and are common in similar healthcare settings, but differ mainly in scheduling and employment structure.

Is working PRN registered nurse worth it?

Working as a PRN registered nurse offers flexibility in scheduling and the ability to choose shifts based on availability, which can improve work-life balance. However, PRN positions often have variable hours and may lack benefits like health insurance or paid time off, so their value depends on individual priorities and financial needs.

What does a PRN registered nurse do?

A PRN registered nurse provides healthcare services on an as-needed basis, often working flexible or temporary shifts in hospitals, clinics, or other medical settings. They perform patient assessments, administer medications, and assist with procedures, requiring active RN licensure and relevant clinical skills. PRN nurses typically do not have a fixed schedule and may work multiple facilities or units based on staffing needs.

What are the most commonly searched types of Prn Rn jobs in Lexington, SC?

The most popular types of Prn Rn jobs in Lexington, SC are:

What job categories do people searching Prn Rn jobs in Lexington, SC look for?

The top searched job categories for Prn Rn jobs in Lexington, SC are:

What cities near Lexington, SC are hiring for Prn Rn jobs?

Cities near Lexington, SC with the most Prn Rn job openings:

Infographic showing various Prn Rn job openings in Lexington, SC as of September 2026, with employment types broken down into 7% As Needed, 29% Full Time, 57% Part Time, and 7% Contract. Highlights an 100% In-person job distribution, with an average salary of $64,937 per year, or $31.2 per hour.

Hospice Registered Nurse (RN) - PRN

Columbia, SC

$38 - $41.30/hr

Per diem

Retirement

Re-posted 7 days ago


Job description

It’s been said that people will forget what you say and what you do, but never how you make them feel. Hospice nurses are special in that they bring not only strong clinical skills but also a heartfelt commitment to ensuring that patients and their families receive comfort, understanding, and unwavering support during one of life's most meaningful transitions. We are seeking a compassionate and experienced Hospice Registered Nurse (RN) who is dedicated to leading with empathy, clinical excellence, and a deep respect for patient dignity. In this vital role, you will deliver exceptional, patient-centered end-of-life care that honors everyone's journey.

Guided by our mission to honor God through the enrichment of human life, Interim HealthCare has been a trusted leader in home health and hospice services across South Carolina since 1979 and is proud to be recognized as a 9x Top Workplace. We believe exceptional care begins with supported nurses, and we foster an environment where clinicians are respected, empowered, and equipped to do meaningful work—if you’re ready to make a lasting difference in patients’ lives, we invite you to join our team.

Why You’ll Love Working with Interim 

As a PRN Hospice Registered Nurse (RN) with Interim, you’ll enjoy:

  • Competitive compensation ranging from $38.00 - $41.30 per hour DOE, plus mileage reimbursement
  • Flexible scheduling that supports true worklife balance and autonomy
  • Dedicated 1:1 patient care, allowing you to focus on quality care, not volume
  • 401(k) with employer match to help you plan confidently for the future
  • Support for your growth and well-being, including free CEUs, tuition assistance, and fitness reimbursement

What You’ll Do 

As a PRN Hospice Registered Nurse (RN), you will:

  • Perform nursing assessments during scheduled, as-needed, or on-call visits to evaluate the patient’s physical condition, symptoms, and immediate care needs.
  • Assess changes in the patient’s condition and promptly communicates significant findings to the RN Case Manager, physician, and/or appropriate members of the interdisciplinary group (IDG).
  • Provide nursing care in accordance with the established plan of care and assists with implementing updates or interventions based on changes in the patient’s condition.
  • Administer medications and treatments as prescribed by the physician and in accordance with hospice policies and nursing standards of practice.
  • Provide interventions to support effective pain and symptom management and evaluates the patient’s response to treatment.
  • Educate patients, families, and caregivers regarding medications, symptom management, comfort measures, disease progression, and when to contact the hospice team for additional support.
  • Coordinate with the RN Case Manager and other IDG members to ensure continuity of care and appropriate follow-up after PRN visits.
  • Respond to changes in patient condition, symptom-management needs, and other urgent clinical concerns within the scope of the PRN assignment.
  • Complete timely and accurate documentation of assessments, interventions, patient/family education, changes in condition, and communication with the hospice care team.
  • Provide compassionate, patient-centered end-of-life care that promotes comfort, dignity, and support for patients and their families.

What You’ll Need 

  • Graduate of an accredited Registered Nurse (RN) program 
  • Active South Carolina RN license or Compact License 
  • Minimum one year of nursing experience 
  • Hospice experience preferred 

Apply Today 

If you are a PRN Hospice Registered Nurse (RN) looking for a rewarding Hospice opportunity in Columbia, SC, we encourage you to apply and join a compassionate, patient focused team.  

Interim HealthCare is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. 

#IHC