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Prn Rn Jobs in Greenville, SC (NOW HIRING)

Simpsonville Post Acute

RN, PRN

Simpsonville, SC · On-site

$33 - $35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

PACS

RN, PRN

Simpsonville, SC · On-site

$33 - $35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

Pacs

RN, PRN

Simpsonville, SC · On-site

$35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

PACS Inc

RN, PRN

Simpsonville, SC · On-site

$33 - $35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

PACS Inc

RN, PRN

Easley, SC · On-site

$34 - $40/hr

Registered Nurse (RN) - PRN $34-$40/hour Easley, SC About Us Powdersville Post Acute is a 60-bed skilled nursing and rehabilitation facility located in Easley, SC, just minutes from downtown ...

PACS

RN, PRN

Easley, SC · On-site

$34 - $40/hr

Registered Nurse (RN) - PRN $34-$40/hour Easley, SC About Us Powdersville Post Acute is a 60-bed skilled nursing and rehabilitation facility located in Easley, SC, just minutes from downtown ...

Pacs

RN, PRN

Powdersville, SC · On-site

$40/hr

Registered Nurse (RN) - PRN $34-$40/hour Easley, SC About Us Powdersville Post Acute is a 60-bed skilled nursing and rehabilitation facility located in Easley, SC, just minutes from downtown ...

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Showing results 21-40

All JobsPrn Rn JobsPrn Rn Jobs in Greenville, SC

Prn Rn information

See Greenville, SC salary details

$18

$34

$50

How much do prn rn jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for prn rn in Greenville, SC is $34.30, according to ZipRecruiter salary data. Most workers in this role earn between $27.36 and $39.57 per hour, depending on experience, location, and employer.

What is a PRN RN?

PRN RNs are registered nurses who work 'pro re nata,' a Latin phrase meaning 'as needed.' These nurses do not have a set schedule but instead fill in shifts when there are staffing shortages or increased patient needs. PRN RNs can work in various healthcare settings, including hospitals, clinics, and nursing homes. This job offers flexibility, but hours and benefits may vary depending on the employer and the frequency of shifts worked.

What are the key skills and qualifications needed to thrive as a PRN RN, and why are they important?

To thrive as a PRN RN, you need a nursing degree, an active RN license, and a solid understanding of clinical procedures and patient care. Familiarity with electronic health records (EHRs), medication administration systems, and common clinical equipment is crucial. Excellent adaptability, communication, and time-management skills help PRN RNs adjust quickly to new settings and work effectively with different teams. These competencies ensure safe, high-quality patient care even in variable or fast-changing environments.

What are some common challenges faced by PRN RNs, and how can they effectively adapt to different units or teams?

PRN (pro re nata, or as-needed) RNs often face the challenge of quickly adapting to various units, patient populations, and workflows since they may float between different departments based on staffing needs. Effective communication, flexibility, and a strong foundational nursing knowledge are crucial for success in this role. Building rapport with permanent staff and familiarizing yourself with each unit’s protocols during orientation can ease transitions and improve patient care. Being proactive in asking questions and seeking clarification helps ensure safe and efficient practice while working in diverse environments.

What is the difference between Prn Rn vs Full-Time Rn?

FeaturePrn RnFull-Time Rn
Work ScheduleAs needed, flexible shiftsScheduled, regular shifts
CertificationsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentHospitals, clinics, home careHospitals, clinics, long-term care
Employer UsageHospitals, staffing agenciesHospitals, healthcare facilities

Prn Rn nurses work on an as-needed basis with flexible hours, ideal for those seeking part-time or supplemental work. Full-Time Rn nurses have scheduled shifts and consistent hours, providing stability and benefits. Both roles require an RN license and are common in similar healthcare settings, but differ mainly in scheduling and employment structure.

Is working PRN registered nurse worth it?

Working as a PRN registered nurse offers flexibility in scheduling and the ability to choose shifts based on availability, which can improve work-life balance. However, PRN positions often have variable hours and may lack benefits like health insurance or paid time off, so their value depends on individual priorities and financial needs.

What does a PRN registered nurse do?

A PRN registered nurse provides healthcare services on an as-needed basis, often working flexible or temporary shifts in hospitals, clinics, or other medical settings. They perform patient assessments, administer medications, and assist with procedures, requiring active RN licensure and relevant clinical skills. PRN nurses typically do not have a fixed schedule and may work multiple facilities or units based on staffing needs.

What are the most commonly searched types of Prn Rn jobs in Greenville, SC?

The most popular types of Prn Rn jobs in Greenville, SC are:

What are popular job titles related to Prn Rn jobs in Greenville, SC?

For Prn Rn jobs in Greenville, SC, the most frequently searched job titles are:

What job categories do people searching Prn Rn jobs in Greenville, SC look for?

The top searched job categories for Prn Rn jobs in Greenville, SC are:

What cities near Greenville, SC are hiring for Prn Rn jobs?

Cities near Greenville, SC with the most Prn Rn job openings:

Prn Rn jobs near you
Infographic showing various Prn Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 29% As Needed, 42% Full Time, and 29% Part Time. Highlights an 100% In-person job distribution, with an average salary of $71,335 per year, or $34.3 per hour.

Registered Nurse (RN) - PRN Tier 2 - Vascular and Stroke Care

Spartanburg Regional Medical Center

Spartanburg, SC • On-site

Per diem

Re-posted 20 days ago

Key responsibilities

  • Provide inpatient nursing care to patients in accordance with organizational policies and clinical standards.

  • Document all aspects of patient care and monitor patient progress using electronic health records.

  • Collaborate with patients, families, and healthcare team members to develop, implement, and evaluate individualized care plans.

Spartanburg Regional Healthcare System rating

6.7

Company rating: 6.7 out of 10

Based on 117 frontline employees who took The Breakroom Quiz

534th of 898 rated healthcare providers

Job description

Job Requirements
Unit Summary
Welcome to 5 Main, a 32-bed acute care unit for med/surg/tele patients. Our patient-focused approach and monitored beds create a nurturing environment for extensive learning and skill development.
On 5 Main, teamwork is at the heart of our success. At the helm of 5 Main, you'll find our Nurse Manager, a seasoned nurse with over 20 years of experience, all of it on this very unit. With a diverse background in various leadership roles, she's not just a fantastic leader but also an exceptional teacher with a wealth of clinical knowledge. Our Assistant Nurse Manager, with a decade of experience on 5 Main, is equally dedicated and supportive. Their active presence on the unit fosters strong teamwork, and they delight in organizing teambuilding activities and contests, both within and outside of work.
Our long-tenured team embodies hard work, support, compassion, and excellence in clinical skills. We cherish the opportunity to partner with patients and their families, making a positive impact on their care journey. If you're seeking a rewarding opportunity to make a difference, we invite you to apply now!
Position Summary
The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's involvement in the communities we serve.
The Tier 2 PRN RN commits to 3 weekend or night shifts every 6 weeks and a minimum of 32 hours per pay period.
Minimum Requirements
Education
  • Graduate of an approved / accredited School of Nursing

Experience
  • Novice to expert nurse

License/Registration/Certifications
  • Current RN licensure in the State of South Carolina or Compact State
  • BLS - may secure certification post-hire.

Preferred Requirements
Preferred Education
  • N/A

Preferred Experience
  • One Year of Recent RN experience within the past 5 years

Preferred License/Registration/Certifications
  • N/A

Core Job Responsibilities
  • Basic computer skills
  • Demonstrates competency utilizing electronic health record.
  • Documents all aspects of patient care by following established charting procedure to show the patient's progress or any change in the patient's condition.
  • Adheres to system required standards of behavior.
  • Adheres to proper chain of command.
  • Meets continuing education requirements, demonstrates knowledge of and ensures compliance with clinical expectations of regulatory agency requirements (DNV, DHEC, CMS)
  • Effectively communicates with patients, families, providers, and hospital associates.
  • Knowledgeable in use of and response to Facility Alert, Medical Alert, Medical Emergency Systems
  • Develops, implements, evaluates, and revises plan of care based on physical, psychosocial, spiritual, and educational needs of the patient/family.
  • Provides a safe patient care environment.
  • Collaborates with patient, families, and other members of the health care team to determine patient priorities, treatments.
  • Coordinates, provides, and directs patient teaching activities.
  • Initiates and facilitates interdisciplinary collaboration to enhance outcome.
  • Seeks necessary assistance in completing nursing interventions to assure positive patient outcomes.
  • Responsible for demonstrating competencies for new equipment, procedures, and annual competency validation.
  • Provides clinical guidance to students and ancillary staff.
  • Successfully completes hospital and unit-based orientation programs and annual competencies.
  • Formulates a plan for personal professional growth.
  • Recommends the need to develop or revise policies and procedures.
  • Serves on unit-based committees and as assigned.
  • Prioritizes nursing interventions for an assigned group of patients.
  • Critically assesses assigned patients' medical history, admitting diagnosis and physician's orders, obtains nursing history, performs physical assessment, evaluates diagnostic data, and interviews patient and family to determine patient needs.
  • Ability to properly assess and prioritize multiple patients according to the severity of illness, injury, and/or needs.
  • Able to assess, critically think, and provide quality patient care inherent to the fast-paced, dynamic environment.
  • Professionally interact and communicate with patients from all age groups, diverse backgrounds, and varying educational levels. Also, must be able to communicate and treat patients that may be confused, irrational, agitated, and/or uncooperative.
  • Utilizes Nursing standards and protocols to manage and stabilize emergencies until provider responds.
  • Demonstrates knowledge of professional nursing practice and theory
  • Assures continuity of care through effective decision making resulting in quality patient care
  • Remains committed to unit, department, and division goals.
  • Support patient experience initiatives
  • Participates in purposeful rounding, bedside shift reports, and huddles.
  • Demonstrates knowledge and ensures compliance with clinical expectations regarding regulatory agency requirements (DNV, DHEC, CMS)
  • Demonstrates appropriate standards of care, clinical pathways, and milestones to drive the plan of care.
  • Complies with current policies and procedures.
  • Other Duties as assigned.

What Spartanburg Regional Healthcare System employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

Spartanburg Regional Healthcare System logo

About Spartanburg Regional Healthcare System

Sourced by ZipRecruiter

Spartanburg Regional Healthcare System is a leader in the healthcare industry, located in Spartanburg, SC, US. As a comprehensive health system, it offers services encompassing everything from wellness, prevention, and care coordination to specific medical treatments for a wide range of diseases and health issues. Spartanburg Regional Healthcare System was founded in 1921 and has since developed a reputation for excellence and innovative care, growing to include six hospitals, 100 medical offices, 8,000 associates and more than 900 medical staff.

Industry

Recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Spartanburg, SC, US

Year founded

1921

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