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Principal Project Manager Jobs in Oregon (NOW HIRING)

West Yost

Principal Engineer - Treatment

Lake Oswego, OR · Hybrid

$140K - $180K/yr

Principal Engineer - Treatment The Principal Engineer in Treatment Group is responsible for ... This includes business development and proposal writing along with managing and engaging in project ...

West Yost

Principal Engineer - Treatment

Lake Oswego, OR · Hybrid

$140K - $180K/yr

Principal Engineer - Treatment The Principal Engineer in Treatment Group is responsible for ... This includes business development and proposal writing along with managing and engaging in project ...

Baylor Scott & White Health

$62.52/hr

The Project Manager will collaborate closely with physician investigators, research coordinators ... Experience working with physicians, principal investigators, research coordinators, and healthcare ...

Integrus

Office Manager & Billing Specialist

Portland, OR · On-site

$60K - $75K/yr

You'll work closely with Principals, Project Managers, consultants, clients, and employees across the firm while helping to create a welcoming workplace and ensuring our financial and administrative ...

New

Integrus

Office Manager & Billing Specialist

Portland, OR · On-site

$60K - $75K/yr

You'll work closely with Principals, Project Managers, consultants, clients, and employees across the firm while helping to create a welcoming workplace and ensuring our financial and administrative ...

Populous

Project Architect

Portland, OR · On-site

$89K - $110K/yr

Maintain a collaborative professional working relationship with the Project Leadership Team (Project Designer, Project Manager, and Principal in Charge). * Act as an intermediary between the client ...

Populous

Project Architect

Portland, OR · Hybrid

$89K - $110K/yr

Maintain a collaborative professional working relationship with the Project Leadership Team (Project Designer, Project Manager, and Principal in Charge). * Act as an intermediary between the client ...

GFT.

$147K - $175K/yr

GFT is seeking experienced Principal Substation Engineers (Electrical Engineers) to join our ... May act in th capacity of project manager, client manager or capture/proposal manager. * Build ...

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Showing results 41-60

All JobsPrincipal Project JobsPrincipal Project Manager JobsPrincipal Project Manager Jobs in Oregon

Principal Project Manager information

See Oregon salary details

$47.6K

$111K

$179.2K

How much do principal project manager jobs pay per year?

As of Aug 9, 2026, the average yearly pay for principal project manager in Oregon is $111,042.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,800.00 and $135,900.00 per year, depending on experience, location, and employer.

What is the difference between Principal Project Manager vs Senior Project Manager?

AspectPrincipal Project ManagerSenior Project Manager
CredentialsPMI PMP, PgMP, or equivalent; extensive experiencePMP or similar; significant project management experience
Work EnvironmentStrategic leadership, cross-departmental projectsManaging complex projects, team oversight
Employer & Industry UsageLarge corporations, consulting firms, tech companiesVaried industries, mid to large organizations

The Principal Project Manager typically holds higher-level certifications and leads strategic initiatives across departments, whereas the Senior Project Manager focuses on managing complex projects and teams within specific domains. Both roles require extensive project management experience, but the Principal often has broader responsibilities and influence.

What are the key skills and qualifications needed to thrive as a principal project manager, and why are they important?

To thrive as a Principal Project Manager, you need advanced project management expertise, strategic planning abilities, and a track record of leading large, complex projects, often backed by a bachelor's or master's degree and PMP or similar certification. Familiarity with project management tools like Microsoft Project, Jira, or Primavera, as well as experience with budget and resource management systems, is essential. Outstanding leadership, stakeholder communication, and problem-solving skills set top performers apart in this role. These competencies ensure effective project delivery, risk mitigation, and alignment with organizational goals on high-stakes initiatives.

Is a principal project manager a high position?

A principal project manager is a senior-level role responsible for overseeing large or complex projects, often involving strategic planning and leadership. It is considered a high position within project management, typically requiring extensive experience, certifications like PMP, and strong leadership skills.

What is a principal project manager?

Principal Project Managers are senior professionals responsible for overseeing large, complex projects or multiple project teams within an organization. They provide strategic direction, manage key stakeholders, and ensure successful project delivery within scope, time, and budget constraints. In addition to managing projects, they mentor junior project managers, establish best practices, and contribute to organizational goals through leadership and expertise.

How does a principal project manager typically collaborate with cross-functional teams to ensure project success?

A Principal Project Manager works closely with diverse teams—such as engineering, finance, marketing, and operations—to align project objectives and timelines. They facilitate regular meetings, establish clear communication channels, and proactively resolve conflicts or bottlenecks. By leveraging their leadership and organizational skills, they ensure that all stakeholders are informed, engaged, and contributing toward common goals. This collaborative approach is essential for navigating complex projects and delivering successful outcomes.
What are popular job titles related to Principal Project Manager jobs in Oregon? For Principal Project Manager jobs in Oregon, the most frequently searched job titles are:
What job categories do people searching Principal Project Manager jobs in Oregon look for? The top searched job categories for Principal Project Manager jobs in Oregon are:
What cities in Oregon are hiring for Principal Project Manager jobs? Cities in Oregon with the most Principal Project Manager job openings:
Principal Project Manager jobs near you
Infographic showing various Principal Project Manager job openings in Oregon as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $111,042 per year, or $53.4 per hour.

Principal Technical Sub-Project Manager (Drug Product Filling & Compounding Equipment)

Genentech, Inc.

Hillsboro, OR • On-site

$109K - $204K/yr

Full-time

Re-posted 24 days ago

Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

11th of 86 rated pharmaceutical

Job description

This role is an integral part of our Equipment Engineering team, dedicated to delivering cutting-edge solutions for drug product filling and compounding systems that ensure safe, efficient, and compliant pharmaceutical manufacturing. As a member of this team, you will collaborate with global stakeholders, equipment manufacturers, and multidisciplinary project teams to drive the successful delivery of capital projects. With a focus on innovation, quality, and operational excellence, you will contribute to advancing Roche's mission of providing life-changing medicines to patients worldwide.
The Opportunity
As a Principal Technical Sub-Project Manager (Drug Product Filling & Compounding Equipment), you will lead and manage the technical execution of drug product filling and compounding equipment sub-projects, driving collaboration across global teams and ensuring compliance with industry standards. You will be accountable for delivering innovative, high-quality solutions that support the manufacturing of Roche's life-saving medicines. Additionally, you will:
  • Independently plan, design, and implement mechanical and process engineering projects, ensuring full compliance with Roche Guidelines, Global Standards, and Health Authority Requirements.
  • Manage the approved sub-project budget and schedule, define priorities, and provide regular updates on progress, risks, mitigation strategies, and escalations.
  • Serve as the primary interface with equipment manufacturers, managing technical specifications, design reviews, performance validation, and compliance requirements.
  • Lead and coordinate Factory Acceptance Tests (FATs), Site Acceptance Tests (SATs), commissioning, and qualification activities to ensure operational readiness of equipment.
  • Direct and manage external engineering firms, service providers, and contractors to ensure timely and quality-compliant project execution.
  • Guide overall project scope, including options analysis, project planning, detailed scheduling, and resource allocation.
  • Mentor and coach less experienced engineers, fostering technical growth and professional development across the team.

Who You Are
  • You possess a Bachelor's Degree in Mechanical Engineering, Chemical Engineering, or a related discipline with 8+ of experience, or a Master's Degree with 6+ years of experience in pharmaceutical/biopharmaceutical filling and compounding equipment; an MS in Engineering and/or an MBA is preferred.
  • You possess extensive years of experience in international management of capital projects related to drug product filling and compounding equipment, with typical project budgets ranging from 15 to 50m CHF.
  • You possess 8+ years of specific operational experience with filling and compounding systems and equipment, including aseptic filling, lyophilization, vial/syringe filling, and aseptic compounding systems.
  • You have proven experience collaborating with equipment manufacturers, leading FAT/SAT efforts, and managing equipment commissioning and qualification activities.
  • You possess significant knowledge with regulatory compliance (FDA, EMA) and GMP requirements for filling and compounding operations, with demonstrated success in delivering complex projects in pharmaceutical manufacturing environments.
  • Significant travel (50% +) assignment requiring weekly commuting and/ or temporary remote assignment as required to meet the business need (including on-site presence during FAT/SAT activities). International project assignment of 1 to 3 years as required to meet the business need.

The expected salary range for this position based on the primary location of Oregon is $109,900 - $204,100. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed in this link.
This is an on-site position; no remote options are available at this time.
Relocation benefits are not approved for this posting.
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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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About Genentech

Sourced by ZipRecruiter

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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