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Preclinical Cro Jobs (NOW HIRING)

Perform an inventory review for incoming CRO clinical study files; receive, index, and file preclinical study records; responsible for offsite archival of documents; participate in periodic file room ...

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$44K

$103.2K

$239.5K

How much do preclinical cro jobs pay per year?

As of Jul 14, 2026, the average yearly pay for preclinical cro in the United States is $103,249.00, according to ZipRecruiter salary data. Most workers in this role earn between $56,000.00 and $200,000.00 per year, depending on experience, location, and employer.

What are the typical career advancement opportunities for someone working in a Preclinical CRO role?

Professionals in Preclinical CRO roles can advance their careers by moving into senior scientist, project management, or team leadership positions, often taking on greater responsibility for study design and client management. With experience, it's also common to specialize in specific therapeutic areas or regulatory submission processes, or to progress to roles overseeing entire departments or business units. Many CROs offer ongoing training and development, enabling professionals to stay current with industry trends and broaden their expertise. Advancement often depends on demonstrated leadership, technical excellence, and a strong track record in delivering high-quality, compliant results. This environment rewards proactive learning and collaboration, providing ample opportunities for long-term career growth.

What is a Preclinical CRO job?

A Preclinical CRO (Contract Research Organization) job involves supporting pharmaceutical and biotechnology companies in conducting preclinical research before human trials. Professionals in this role assist with study design, laboratory testing, regulatory compliance, and data analysis to evaluate the safety and efficacy of drug candidates. They work with scientists and researchers to conduct in vitro and in vivo studies, ensuring high-quality results that meet regulatory standards. Preclinical CRO employees may specialize in toxicology, pharmacokinetics, bioanalysis, or other key areas that contribute to drug development.

What are the key skills and qualifications needed to thrive in the Preclinical Cro position, and why are they important?

To thrive as a Preclinical CRO (Contract Research Organization) professional, you need a solid background in life sciences or pharmacology, experience in laboratory research, and a strong understanding of regulatory compliance in drug development. Expertise with laboratory information management systems (LIMS), data analysis tools, and familiarity with GLP (Good Laboratory Practice) certification are typically important. Strong attention to detail, project management skills, and effective communication are valuable soft skills for success in this role. These competencies ensure accurate preclinical study execution, compliance with regulatory standards, and effective collaboration within multidisciplinary teams.

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Preclinical Safety Profiling Expert, Principal Scientist

Novartis Farmacéutica

Cambridge, MA • Hybrid

$119K - $222K/yr

Full-time

Medical, Life, Retirement

This job post has expired today. Applications are no longer accepted.


Job description

Cambridge, MA – Principal Scientist I / II – Hybrid

Position within the Novartis Biomedical Research Translational Medicine Unit. The Preclinical Safety (PCS) department provides world‑class preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state‑of‑the‑art regulatory compliance.

As a Preclinical Safety Profiling (PSP) Expert, you will join our global PCS team to help unleash the power of early safety screening and profiling approaches for advancing translational safety assessment and to drive drug discovery and development. You will bring your curious, innovative, and collaborative mindset to leverage a wealth of non‑clinical safety‑related data generated within our department and deploy state‑of‑the‑art laboratory science and data exploration methods to accelerate the advancement of innovative medicines.

Key Responsibilities
  • Design and execute the early safety screening & profiling strategies associated with secondary pharmacology and cardiovascular safety, in collaboration with internal and external stakeholders.
  • Serve as the primary interface between PCS and our CRO partners.
  • Manage internal relationships with PSP subject matter experts and the outsourcing resource group; further develop data internalization processes and manage outsourcing budget.
  • Effectively communicate with stakeholders, including experimental design, data quality, timeline requirements and flowchart planning.
  • Understand and execute agreed business strategy defined by local and global Preclinical Safety Profiling requirements, ensuring appropriate coordination of projects.
  • Participate in cross‑functional early safety screening & profiling collaborations with Novartis Biomedical Research partners to support the early derisking of compounds, drug targets, and therapeutic modalities.
  • Deliver clear and concise presentations for audiences with different expertise.
  • Collaborate with cross‑functional partners to provide scientific and strategic input to support the early derisking of compounds, drug targets, and therapeutic modalities.
  • Ensure quality and compliance of data generation, analyses and resultant reports.
Essential Requirements
  • Advanced Degree or Bachelor's in Pharmacology, Toxicology, or a related field.
  • 5+ years of relevant experience in pharmacology or toxicology.
  • Understanding of hazard identification and risk assessment associated with drug ADME, off‑target mitigation and cardiovascular safety.
  • Familiarity with early drug discovery processes.
  • Experience with data integrity and quality assurance practices.
  • Ability to articulate solutions and recommendations to business users, present analytical content concisely and influence outcomes of predictive safety profiling contributions.
  • Collaborative skills with internal stakeholders, external partners, and cross‑functional teams to solve critical business problems, propose operational efficiencies and innovative approaches.
  • Familiarity with visualization tools to increase efficiency and quality of data communication and interpretation.

This is a dual level posting. The final level & title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.

Compensation and Benefits
  • Salary ranges: Principal Scientist I: $114,100–$211,900 per year; Principal Scientist II: $119,700–$222,300 per year.
  • Performance‑based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
  • US‑based eligible employees receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and additional benefits.
  • Generous time‑off package including vacation, personal days, holidays and other leaves.

Payroll and benefits details will be discussed during the interview process.

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