Plant Kinetics Jobs in Indiana (NOW HIRING)

We are seeking passionate and agile chemists to join the PTE team and help bring the Lilly Medicine Foundry’s vision to life.

• Facilitate the transfer of chemical processes from development laboratories to pilot plant operations (including kilo-scale or pilot-scale production), enabling successful transition to early-phase cGMP manufacturing of kilogram quantities of API required for clinical trial supply.
• Operate and troubleshoot kilo-scale equipment including multi‑purpose reactors, filtration systems, drying equipment (including AFD and tray dryer).
• Apply chemical engineering principles (heat/mass transfer, reaction kinetics, thermodynamics, fluid dynamics) to scale‑up calculations and equipment sizing.
• Develop and apply appropriate cake filtration models to predict filtration rate, cake resistance, and deliquoring performance, and design and execute filtration wash studies.
• Apply appropriate modeling or semi‑empirical approaches to predict and control particle size distribution (PSD) during crystallization.
• Actively involved in receiving chemical process from early phase process research and development labs and evaluating the safety of the incoming procedures in collaboration with the chemist and safety group.
• Document: author, review technical documents, including SOPs, batch records, campaign summary reports, and deviation reports.
• Perform and document Definitive Lab Trials of crystallization step to confirm plant readiness.
• Perform familiarization reactions to ensure plant readiness of process steps with focus on crystallization and filtration at the Lilly Medicine Foundry.
• Order and stage process‑related GMP consumables and equipment parts for kilolab runs.
• Be efficient with summarizing and presenting experimental results and challenges.
• Analyze data to make fact‑based decisions.
• Maintain a well‑organized and detailed lab notebook to enable the preparation of technical packages/technical transfers and accurate replication in receiving labs.
• Process improvement: apply scientific knowledge to identify areas for improvement and implement new technologies or procedures.
• Contribute to process troubleshooting and investigations by supporting process deviations, quality events, and non‑conformances.
• Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.

• BS or MS in Chemical Engineering or a closely related discipline.
• 8+ years of industry experience in pharmaceutical process development, pilot plant operations, or chemical manufacturing.
• Qualified applicants must be authorized to work in the United States on a full‑time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.

• Deep technical interest and understanding in the field of Chemical Engineering.
• Direct hands‑on experience with operating kilo‑scale or pilot‑scale chemical processing equipment.
• Experience with DeltaV, Dynochem, Aspen, and/or electronic lab notebooks.
• Experience with crystallization development including polymorph control, nucleation/growth kinetics, seeding strategies, and PSD control.
• Expertise in filtration modeling and ability to fit model parameters from lab data and apply to pilot equipment sizing and optimization.
• Highly motivated, able to learn rapidly, and demonstrates strong attention to detail.
• Good understanding of FDA guidelines and cGMP requirements.
• Ability to prioritize multiple activities and manage ambiguity.
• Demonstrated ability to drive projects and accept change.
• Excellent written and verbal communication skills for technical report writing, presentations, and effective collaboration across teams.
• Proven ability to analyze data, perform root cause analysis, and resolve complex technical challenges.
• Ability to work cross‑functionally across disciplines and levels with process chemists, analytical chemists, chemical technicians, safety and quality representatives.

• Initial location at Parkwood West, Indianapolis.
• Permanent location at the new Lilly Medicines Foundry in Lebanon, Indiana.
• Limited domestic and international travel (< 5%) may be required for this role.
• Role requires ability to work in manufacturing and laboratory environments.
• May be required to provide support outside of normal working hours including nights or weekends.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form https://careers.lilly.com/us/en/workplace-accommodation for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 – $171,600. Full‑time equivalent employees will also be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company‑sponsored 401(k) pension, vacation benefits, eligibility for medical, dental, vision and prescription drug benefits, flexible benefits such as healthcare and/or dependent day care flexible spending accounts, life insurance and death benefits, certain time off and leave of absence benefits, and well‑being benefits such as employee assistance program, fitness benefits and employee clubs and activities. Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.