... pharmacokinetics (PK), pharmacodynamics (PD), PK/PD modeling and simulation, PBPK modeling, metabolic profiling, and exposure-response analyses, ensuring robust dose selection, characterization of ...
... pharmacokinetics (PK), pharmacodynamics (PD), PK/PD modeling and simulation, PBPK modeling, metabolic profiling, and exposure-response analyses, ensuring robust dose selection, characterization of ...
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
Clinical Pharmacology faculty and staff are national leaders in pharmacogenetics, institutional leaders in health equity research, and outstanding clinicians, using pharmacology and toxicology to ...
Clinical Pharmacology faculty and staff are national leaders in pharmacogenetics, institutional leaders in health equity research, and outstanding clinicians, using pharmacology and toxicology to ...
Associate Scientific Director, Clinical Pharmacology
$144K - $240K/yr
... Pharmacokinetics, Pharmaceutics or PharmD or other suitable related fields * 5+ years relevant industry experience (clinical pharmacology and/or clinical PK/PD) * Ability to analyze and interpret PK ...
Associate Scientific Director, Clinical Pharmacology
$144K - $240K/yr
... Pharmacokinetics, Pharmaceutics or PharmD or other suitable related fields * 5+ years relevant industry experience (clinical pharmacology and/or clinical PK/PD) * Ability to analyze and interpret PK ...
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
Sr. Scientific Director, Clinical Pharmacology
Indiana, PA · On-site
$150 - $200/hr
Master's in Pharmacokinetics, Pharmaceutical Sciences or closely related discipline AND Master's in Pharmacokinetics, Pharmaceutical Sciences or closely related discipline and 13+ years of relevant ...
Sr. Scientific Director, Clinical Pharmacology
Indiana, PA · On-site
$150 - $200/hr
Master's in Pharmacokinetics, Pharmaceutical Sciences or closely related discipline AND Master's in Pharmacokinetics, Pharmaceutical Sciences or closely related discipline and 13+ years of relevant ...
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
This faculty position in Pharmacokinetics balances local campus interests with program imperatives and the needs of the discipline while maintaining ongoing scholarly activities. The position reports ...
Associate Scientific Director, Clinical Pharmacology
$144K - $240K/yr
... Pharmacokinetics, Pharmaceutics or PharmD or other suitable related fields * 5+ years relevant industry experience (clinical pharmacology and/or clinical PK/PD) * Ability to analyze and interpret PK ...
Associate Scientific Director, Clinical Pharmacology
$144K - $240K/yr
... Pharmacokinetics, Pharmaceutics or PharmD or other suitable related fields * 5+ years relevant industry experience (clinical pharmacology and/or clinical PK/PD) * Ability to analyze and interpret PK ...
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
New
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
New
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
New
Leads Clinical Pharmacology/PK/PD aspects of multiple projects. Responsible for critically evaluating technical and scientific aspects along with Clinical Pharmacology and Pharmacometrics management.
New
Director, Clinical Pharmacology
Waltham, MA · On-site
$130 - $170/hr
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Director, Clinical Pharmacology
Waltham, MA · On-site
$130 - $170/hr
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Clinical Pharmacologist - PK/PD Expert
New York, NY · Remote
$120 - $170/hr
... pharmacokinetics, or a related field, MD , or equivalent. * 20-25 hours/week availability, minimum; 30+ preferred. * Experience supporting pre-market (Phases 1-3) programs as a clinical ...
Posted today
Quick apply
Clinical Pharmacologist - PK/PD Expert
New York, NY · Remote
$120 - $170/hr
... pharmacokinetics, or a related field, MD , or equivalent. * 20-25 hours/week availability, minimum; 30+ preferred. * Experience supporting pre-market (Phases 1-3) programs as a clinical ...
Posted today
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Quick apply
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Quick apply
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Conceive and execute novel scientific research or development in Clinical Pharmacology that achieves projects and Clinical Pharmacology and Pharmacometrics (CPPM) goals. Generate new PK/PD proposals ...
Conceive and execute novel scientific research or development in Clinical Pharmacology that achieves projects and Clinical Pharmacology and Pharmacometrics (CPPM) goals. Generate new PK/PD proposals ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Quick apply
Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development ...
Pharmacokinetics information
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$24.76 - $31.84
3% of jobs
$31.84 - $38.92
4% of jobs
$38.92 - $46
9% of jobs
$46 - $53.08
5% of jobs
$54.30 is the 25th percentile. Wages below this are outliers.
$53.08 - $60.16
17% of jobs
The median wage is $63.26 / hr.
$60.16 - $67.24
25% of jobs
$71.78 is the 75th percentile. Wages above this are outliers.
$67.24 - $74.32
17% of jobs
$74.32 - $81.40
9% of jobs
$81.40 - $88.48
6% of jobs
$88.48 - $95.56
2% of jobs
$95.56 - $102.64
1% of jobs
$24
$64
$102
How much do pharmacokinetics jobs pay per hour?
What is pharmacokinetics?
A pharmacokinetics job involves studying how drugs are absorbed, distributed, metabolized, and excreted in the body. Professionals in this field analyze drug concentration data to optimize dosing, improve drug formulations, and ensure safety and efficacy. They work in pharmaceutical companies, regulatory agencies, or research institutions, collaborating with pharmacologists and clinicians. Key responsibilities include designing pharmacokinetic studies, interpreting data, and contributing to drug development and regulatory submissions.
What does someone working in pharmacokinetics do?
Professionals in Pharmacokinetics are responsible for designing and analyzing studies to understand how drugs are absorbed, distributed, metabolized, and excreted in the body. Their daily activities often include data collection and interpretation, building pharmacokinetic models, preparing reports, and presenting findings to research teams or regulatory authorities. Collaboration with clinical researchers, toxicologists, and regulatory staff is common to ensure comprehensive drug development and approval processes. The role is both analytical and collaborative, offering opportunities to contribute meaningfully to new therapies while developing specialized expertise in a dynamic and innovative field.
What skills and qualifications are needed for pharmacokinetics?
To thrive in Pharmacokinetics, a strong background in pharmaceutical sciences, biology, or chemistry—typically at the graduate level—is essential, along with expertise in ADME (Absorption, Distribution, Metabolism, and Excretion) processes. Proficiency with specialized software such as WinNonlin, Phoenix, NONMEM, or similar pharmacokinetic modeling tools, as well as familiarity with regulatory guidelines, is highly valued. Strong analytical thinking, attention to detail, clear communication, and the ability to collaborate effectively with cross-disciplinary teams help set candidates apart. These skills are crucial for ensuring accurate data analysis, successful drug development, and regulatory compliance in the pharmaceutical industry.
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Full-time
Re-posted 12 days ago
Job description
Cytokineticsis a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
At Cytokinetics, each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious, compassionate, and collaborative individuals who are driven to make a positive impact.
Cytokinetics is seeking a Head of Clinical Pharmacology to provide strategic leadership for clinical pharmacology and model-informed drug development across our portfolio. Reporting to the Chief Medical Officer, this individual will lead the development and execution of integrated clinical pharmacology strategies from First-in-Human through registration and lifecycle management.
The Head of Clinical Pharmacology will serve as the subject matter expert for clinical pharmacology, pharmacokinetics (PK), pharmacodynamics (PD), PK/PD modeling and simulation, PBPK modeling, metabolic profiling, and exposure-response analyses, ensuring robust dose selection, characterization of drug-drug interaction profiles, , and regulatory alignment. This role requires deep expertise in translational science, pharmacometrics, and global regulatory requirement in late-stage development.
Key Responsibilities
Study Design & Execution
Design and provide oversight for Phase I and early Phase II studies, including adaptive dose escalation strategies.
Ensure PK sampling strategies and bioanalytical plans.
Collaborate with Clinical Operations and Biostatistics to ensure high-quality data collection and analysis.
Interpret emerging safety, PK, and PD data to guide dose escalation and program advancement.
Lead dose selection rationale for FIH, Phase II, and Phase III trials.
Clinical Pharmacology Strategy
Develop and implement comprehensive clinical pharmacology strategies spanning FIH, SAD/MAD, food effect, drug-drug interaction (DDI), QT assessment, renal/hepatic impairment, intrinsic/extrinsic factor studies, and special populations.
Lead model-informed drug development (MIDD) approaches, integrating nonclinical, translational, and clinical data to support rational dose selection and optimization.
Oversee population PK analyses, exposure-response modeling, covariate analyses, simulations, and scenario planning to inform development decisions.
Drive quantitative dose justification for Phase III trials and regulatory submissions.
Regulatory Leadership
Author and oversee clinical pharmacology sections of INDs, IBs, briefing documents, NDA/MAA submissions, and responses to regulatory queries.
Lead clinical pharmacology preparation for FDA, EMA, and other global health authority interactions.
Provide strategic input into labeling language related to dosing, special populations, and DDIs.
Maintain current knowledge of evolving regulatory guidance, including FDA MIDD initiatives and ICH guidelines.
Team Leadership and Management
Build and manage internal Clinical Pharmacology capabilities.
Oversee external vendors and consultants.
Mentor and develop scientific staff.
Cross-Functional & Translational Integration
Partner closely with Translational Medicine, Nonclinical Development, and DMPK to ensure seamless integration of exposure-response relationships and biomarker strategy.
Collaborate with clinical research, drug safety, and biometrics on protocol development and data analyses.
Partner with CMC on formulation and bioavailability strategy.
Provide quantitative input into benefit-risk assessment and target product profile refinement.
Serve as a core member of cross-functional program teams and governance committees.
External Collaboration & Scientific Leadership
Oversee pharmacometric and bioanalytical CROs and consultants.
Contribute to scientific publications and external presentations as appropriate.
Represent Cytokinetics externally as a clinical pharmacology expert when required.
Minimum Requirements:
PhD in Clinical Pharmacology, Pharmacometrics, Pharmaceutical Sciences, or related quantitative discipline; or MD, MD/PhD, or PharmD with extensive clinical pharmacology expertise.
10+ years of progressive industry experience in pharmaceutical or biotechnology drug development.
Pharmacometrics experience preferred; Demonstrated expertise in PK/PD modeling, population PK, exposure-response analysis, and simulation methodologies.
Proven experience supporting dose selection and justification for pivotal trials and regulatory submissions.
Direct experience contributing to or leading clinical pharmacology components of NDA/MAA filings strongly preferred.
Experience interacting with FDA, PMDA, and EMA regarding clinical pharmacology strategy.
Strong understanding of ICH, GCP, and global regulatory frameworks.
Experience in cardiovascular, neuromuscular, or related therapeutic areas is a plus.
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Pay Range:
In the U.S., the hiring pay range for fully qualified candidates is $290,430.00 - $357,000.00 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.
Please review ourGeneral Data Protection Regulation (GDPR) policyPRIOR to applying.
Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do - all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.
Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.
Here are some ways to check for authenticity:
We do not conduct job interviews through non-standard text messaging applications
We will never request personal information such as banking details until after an official offer has been accepted and verified
We will never request that you purchase equipment or other items when interviewing or hiring
If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly attalentacquisition@cytokinetics.com
Please visit our website at:www.cytokinetics.com
Cytokinetics is an Equal Opportunity Employer
About CYTOKINETICS
Sourced by ZipRecruiter
Industry
Biotechnology research and development
Company size
51 - 200 Employees
Headquarters location
South San Francisco, CA, US
Year founded
1998