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Per Diem Rn Jobs in Beaufort, SC (NOW HIRING)

PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in ... or per diem shift. This is all driven by the simple idea that better care for our healthcare ...

PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in ... or per diem shift. This is all driven by the simple idea that better care for our healthcare ...

PRN Healthcare is seeking a travel nurse RN PCU - Progressive Care Unit for a travel nursing job in ... or per diem shift. This is all driven by the simple idea that better care for our healthcare ...

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Per Diem Rn information

See Beaufort, SC salary details

$5

$37

$70

How much do per diem rn jobs pay per hour?

As of Aug 6, 2026, the average hourly pay for per diem rn in Beaufort, SC is $37.86, according to ZipRecruiter salary data. Most workers in this role earn between $27.16 and $52.31 per hour, depending on experience, location, and employer.

How does scheduling typically work for a per diem RN, and what level of flexibility can I expect?

As a Per Diem RN, you have the flexibility to choose your shifts based on your availability, which makes this role ideal for those seeking work-life balance or supplemental income. Scheduling is often managed through online portals or direct communication with nurse managers, and you may be asked to fill shifts on short notice to cover staff shortages or peak periods. While you have control over your schedule, keep in mind that the most shifts are often available during weekends, holidays, or less desirable hours. Building strong relationships with staffing coordinators and being open to various shifts can help you secure more consistent work.

What is a per diem RN?

A Per Diem RN is a registered nurse who works on an as-needed basis rather than having a set, full-time schedule. These nurses fill staffing gaps, cover for absences, or help during busy periods at hospitals, clinics, or other healthcare facilities. Per diem RNs often have flexibility in choosing their shifts, but they may not receive the same benefits as full-time staff. This role is ideal for nurses seeking variety and work-life balance.

What is the difference between Per Diem Rn vs Staff Nurse?

AspectPer Diem RnStaff Nurse
CredentialsRegistered Nurse (RN) licenseRegistered Nurse (RN) license
Work EnvironmentVaries daily, short-term assignments, flexible schedulingFull-time or part-time hospital or clinic settings, consistent schedule
Employment TypePer diem, as-needed basisPermanent or temporary staff position
UsageSupplemental staffing, fill-in shiftsPrimary nursing staff in healthcare facilities

Per Diem Rns are registered nurses working on a flexible, as-needed basis, often filling in for staff shortages or covering shifts temporarily. Staff Nurses typically hold full-time or part-time positions with consistent schedules in healthcare facilities. The main difference lies in employment type and scheduling flexibility, with Per Diem Rns offering more adaptability compared to the steady employment of Staff Nurses.

What skills and qualifications are needed to thrive as a per diem RN?

To thrive as a Per Diem RN, you need a valid RN license, strong clinical assessment abilities, and experience across various healthcare settings. Familiarity with electronic health record (EHR) systems and up-to-date certifications such as BLS and ACLS are typically required. Flexibility, strong communication, and the ability to quickly adapt to different teams and environments are standout soft skills. These competencies are vital for delivering safe, effective care while efficiently integrating into new units with minimal orientation.
What are the most commonly searched types of Rn jobs in Beaufort, SC? The most popular types of Rn jobs in Beaufort, SC are:
What cities near Beaufort, SC are hiring for Per Diem Rn jobs? Cities near Beaufort, SC with the most Per Diem Rn job openings:
Infographic showing various Per Diem Rn job openings in Beaufort, SC as of August 2026, with employment types broken down into 2% As Needed, 58% Full Time, 16% Part Time, and 24% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $78,742 per year, or $37.9 per hour.

HIRING: Per Diem Infusion Nurse / Registered Nurse / RN

BrightStar Care

Bluffton, SC

Part-time, Per diem

Posted 5 days ago


Job description

Registered Nurse / Infusion Nurse (RN)
Bluffton, Hilton Head and Beuafort, South Carolina & Savannah, GA | Flexible Scheduling | Immediate Opportunities


Overview

We are actively seeking a dedicated and highly skilled Infusion Nurse / Registered Nurse (RN) to join our dynamic healthcare team. This immediate hiring opportunity offers a chance to work in a fast-paced, patient-centered environment where your expertise in IV therapy, vascular access, and comprehensive nursing care will make a meaningful difference.

The ideal candidate will possess a strong background as an oncology RN or home health RN with IV experience, with open availability to serve clients in the Bluffton and Savannah areas.


Responsibilities of a Registered Nurse / Infusion Nurse
  • Administer IV infusions, medications, and therapies accurately while adhering to aseptic techniques and safety protocols.
  • Perform and maintain vascular access, including IV insertion and care management.
  • Conduct thorough patient assessments, including vital signs, physical examinations, and physiological evaluations to determine appropriate care plans.
  • Monitor patients’ responses to treatments, managing acute pain and providing timely interventions as necessary.
  • Collaborate with multidisciplinary teams to develop individualized care plans for diverse patient populations, including those in hospice, oncology, memory care, or behavioral health settings.
  • Educate patients and their families on treatment procedures, medication administration, and post-care instructions to promote understanding and adherence.

Qualifications of a Registered Nurse / Infusion Nurse
  • Registered Nurse (RN) license in the state of practice (South Carolina or Georgia)
  • Minimum of 1 year of clinical nursing experience (home health RN with IV experience preferred)
  • Experience in IV therapy and vascular access required
  • Background as an oncology RN is a strong plus
  • Current CPR/BLS certification
  • Current TB test (Negative or Non Reactive)
  • Reliable transportation and a valid driver’s license
  • Experience working with diverse patient populations across various settings including emergency room, medical-surgical units, outpatient clinics, or home care environments
  • Proficiency in advanced nursing procedures such as IV insertion, medication administration via injection, and ventilator management

Job Type

Per Diem | Contract | Part-Time | PRN


Why Join BrightStar Care as a Registered Nurse / Infusion Nurse
  • Flexible scheduling – choose the shifts that fit your life
  • Competitive pay
  • Supportive, collaborative team environment
  • Meaningful, relationship-focused work

Ready to Make a Difference?

If you’re passionate about exceptional in-home care and want a role that truly fits your lifestyle, we’d love to hear from you.


BrightStar Care logo

About BrightStar Care

Sourced by ZipRecruiter

At BrightStar Care, we believe that caring is more than just a job- it's a way of life. That's why our caregivers mean so much more to the people, families, and organizations they serve. BrightStar Care nurses, therapists, CNAs, and caregivers deliver professional and compassionate care in the comfort and familiarity of home. We are proud to provide a range of home care services to meet your loved one's unique needs. From companionship, bathing, and hygiene assistance to in-home infusions and medication management, our professional care staff is available 24/7 to help when you need it most.

Industry

Outpatient health care, health care and social assistance, fitness and sports centers and home health care services

Company size

10,000+ Employees

Headquarters location

Gurnee, IL, US