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Pbmc Isolation Jobs (NOW HIRING)

PREDICTA BIOSCIENCES INC

R&D Scientist

Cambridge, MA

Develop and optimize sample processing workflows (whole blood, bone marrow, PBMC isolation) that feed both flow cytometry and NGS/single-cell pipelines * Use FACS to identify rare cell populations ...

Mount Sinai Hospital

Postdoctoral Fellow-MSH

Manhattan, NY · On-site

$53K - $73K/yr

Mice handling, intraperitonial injection, Tissue processing, bone marrow extraction to derive dendritic cells, T-Cell isolation from PBMC by using MACS. Requirements: We are looking for candidates ...

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Pbmc Isolation information

What are the key skills and qualifications needed to thrive as a PBMC isolation specialist, and why are they important?

To thrive as a PBMC Isolation Specialist, you need a solid background in cell biology, laboratory techniques, and typically a bachelor's degree in a life science field. Proficiency with equipment such as centrifuges, pipettes, biosafety cabinets, and familiarity with protocols like Ficoll-Paque density gradient centrifugation is essential. Attention to detail, strong organizational skills, and the ability to follow precise protocols are vital soft skills in this role. These competencies ensure the reliability and reproducibility of isolated peripheral blood mononuclear cells, which are critical for downstream research and clinical applications.

What is the difference between Pbmc Isolation vs Flow Cytometry Technician?

AspectPbmc IsolationFlow Cytometry Technician
Required CredentialsLaboratory technician certification, biology or related degreeLaboratory certification, biology or related degree
Work EnvironmentResearch labs, clinical labsResearch labs, clinical labs
Industry UsageImmunology, hematology, researchImmunology, cell analysis, research

Pbmc Isolation involves extracting peripheral blood mononuclear cells from blood samples, focusing on cell separation techniques. Flow Cytometry Technicians operate instruments to analyze and sort cells, often using cells isolated via Pbmc Isolation. Both roles require similar educational backgrounds and are used in research and clinical settings, but they focus on different steps in cell analysis workflows.

What are some common challenges faced during PBMC isolation and how can they be addressed?

One common challenge in PBMC isolation is maintaining cell viability and yield, especially when working with samples that have been stored or transported. Proper sample handling, prompt processing, and using standardized protocols help minimize cell loss and contamination. Additionally, working in a sterile environment and carefully following centrifugation steps can ensure high-quality results. Collaborating with laboratory staff and adhering to quality control measures are also essential for consistent success in this role.

What is PBMC isolation?

PBMC isolation is the process of separating peripheral blood mononuclear cells (PBMCs) from whole blood. PBMCs include lymphocytes (such as T cells, B cells, and NK cells) and monocytes, which are important for immune research and clinical studies. The isolation is typically performed using density gradient centrifugation, allowing researchers to study immune responses, conduct cell therapies, and perform various laboratory analyses. Proper PBMC isolation is critical for ensuring cell viability and purity in downstream applications.
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Pbmc Isolation jobs near you
Infographic showing various Pbmc Isolation job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 77% Full Time, 11% Part Time, and 9% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution.

Sr. Laboratory Specialist, Cell Lab

Sampled

Piscataway, NJ • On-site

Full-time

Posted 20 days ago

Job description

COMPANY OVERVIEW:
Sampled is a fully integrated laboratory and biorepository with industry-leading storage, sample management, multi-omics, cellular services, and custom clinical kitting. Founded in 1999 as RUCDR at Rutgers University, Sampled operates facilities in the US and UK and is CAP accredited and CLIA licensed. Sampled is committed to providing the highest quality sample storage, processing, and analysis services that enable researchers to make new discoveries and advance human health. When combined with state-of-the-art biobanking facilities, these capabilities provide comprehensive scientific solutions that speed time to quality data.
POSITION SUMMARY:
We are excited to announce the opening of a Senior Laboratory Specialist position in our Cellular Services Group.
The Senior Specialist plays a key role in supporting cell banking and cell culture operations by performing the initiation, expansion, maintenance, characterization, and cryopreservation of induced pluripotent stem cells (iPSCs), fibroblasts, lymphoblastoid cell lines (LCLs), peripheral blood mononuclear cells (PBMCs), and other adherent and suspension cell cultures. This position supports both internally and externally generated cell lines and ensures all laboratory activities are conducted in accordance with established SOPs, quality standards, and aseptic techniques.
Reporting to the Cell Lab Supervisor, the Senior Specialist is responsible for validating incoming samples, processing PBMCs from whole blood, monitoring cell culture health, maintaining accurate laboratory documentation, and supporting high-quality cell banking services. The role also performs routine quality control activities, including alkaline phosphatase (AP) staining, cell counting and viability assessments using the Countess Cell Counter, and cell characterization utilizing the Thermo Fisher Attune Flow Cytometer (FACS). Proficiency in the use of EVOS brightfield and fluorescence microscopy is required to evaluate cell morphology, confluency, and marker expression.
In addition, the Senior Specialist supports product distribution activities by preparing Certificates of Analysis (COAs), shipment manifests, and order documentation for iPSC distribution requests through the Jira ticketing system. The position also contributes to inventory management, reagent and supply tracking, equipment monitoring, daily equipment log maintenance, and overall compliance with laboratory quality and operational requirements. Strong communication skills, attention to detail, and a commitment to maintaining the highest standards of laboratory excellence are essential for success in this role.
Candidates must be located in the New Jersey area and able to work onsite at Sampled's Headquarters in Piscataway.
RESPONSIBILITIES:
  • Perform routine laboratory procedures as required to meet daily lab operation expectations, including whole blood and cell cultures for establishment of transformed lymphocyte cell lines and DNA extractions for genetic studies.
  • Maintain accurate records in the Laboratory Information Management System (LIMS) to ensure sample identity data and sample processing data.
  • Perform quality control and assurance checks as samples are processed, resolve sample discrepancy problems in coordination with laboratory staff, directors and cell services staff.
  • Provide professional level laboratory technical support involving the application of scientific research methods and techniques, as directed by the Laboratory management team.
  • Follow quality control policies and procedures on all aspects of laboratory operations.
  • Take personal responsibility to deliver client services to a consistently high standard.
  • Follow Standard Operating Procedures and adhere to all safety and company policies.
  • Be effective team player, with behaviors reflecting Sampled Core Values: We strive to Delight our Clients, We pursue Excellence in every interaction, process and outcome, We Collaborate to create the best results for our clients and for each other, We are One Team, We Communicate proactively, transparently, and consistently.
  • Perform related responsibilities as needed.

POSITION REQUIREMENTS:
  • Requires a Bachelors or Masters degree in a Life Sciences field, for example Biology, Molecular Biology or Biochemistry.
  • Minimum 2 years' post qualification experience in all aspects of blood processing and cell culture, including iPSCs, PBMC isolation, viability testing, LCL conversion, passaging and cryopreservation.
  • Must be able to read and understand technical documents, and follow Standard Operating Procedures (SOPs)
  • Experienced in Good Laboratory Practice (GLP) and Good Documentation Practice (GDP), with a commitment to laboratory excellence in all activities. Experienced in working with a quality driven system.
  • Must have strong organizational skills, with the ability to conduct and organize laboratory-based business enterprise efficiently and expeditiously whilst maintaining a high level of accuracy and attention to detail. Able to manage multiple tasks.
  • Experienced using laboratory information management systems (LIMS), LabVantage preferred.
  • Able to operate scientific instruments, with good manual dexterity.
  • Excellent verbal and written communication skills.
  • Strong attention to detail.
  • Strong mathematics and analytical skills.
  • Team player with good interpersonal skills.
  • This position will require occasional, sometimes significant, work on weekend and holidays due to the inherent demands of cell processing and culture.
  • Time management skills and ability to work well under pressure.
  • Strong organization skills, with attention to priorities, effectively meeting deadlines and responding in a timely manner.

Salary range $60,000 to $80,000. Salary level will be reflective of qualifications, skills and experience.
Sampled is an Equal Opportunity Employer (M/F/Disabled/Veteran)
Initial closing date for applications: Monday, July 27th 2026

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