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Pairwise Jobs (NOW HIRING)

Data & ML Engineer

$117K - $140K/yr

Implement probabilistic matching, including blocking, candidate generation, pairwise scoring, clustering, and threshold policy * Build deduplication and known-record suppression * Establish ...

Data & ML Engineer

$117K - $140K/yr

Implement probabilistic matching, including blocking, candidate generation, pairwise scoring, clustering, and threshold policy * Build deduplication and known-record suppression * Establish ...

Design and implement posttraining pipelines that combine techniques such as supervised finetuning on curated demonstrations, preference modeling and pairwise ranking, and RLbased alignment approaches ...

Partner with product, research, and engineering teams to implement evaluation metrics (e.g., win rate, inter-annotator agreement, and pairwise preference scoring) Client Partnership & Communication

Design and implement post-training pipelines that combine techniques such as supervised fine-tuning on curated demonstrations, preference modeling and pairwise ranking, and RL-based alignment ...

Showing results 41-60

Pairwise information

See salary details

$35K

$75.6K

$108.5K

How much do pairwise jobs pay per year?

As of Sep 2, 2026, the average yearly pay for pairwise in the United States is $75,617.00, according to ZipRecruiter salary data. Most workers in this role earn between $66,500.00 and $85,000.00 per year, depending on experience, location, and employer.

What are Pairwise jobs?

Pairwise is a biotechnology company specializing in gene editing and agricultural innovation, primarily focusing on developing new varieties of fruits and vegetables. Jobs at Pairwise typically involve roles in research and development, laboratory operations, bioinformatics, regulatory affairs, and business operations. Employees work on advancing CRISPR and other gene-editing technologies to create healthier and more sustainable food options. The company offers opportunities for scientists, engineers, and professionals passionate about applying science to real-world food challenges.

What are the key skills and qualifications needed to thrive as a plant geneticist at Pairwise, and why are they important?

To thrive as a Plant Geneticist at Pairwise, you need a strong background in plant biology, genetics, and molecular biology, typically supported by an advanced degree in a related field. Familiarity with gene editing technologies like CRISPR, genomic data analysis tools, and laboratory information management systems is essential. Strong problem-solving skills, collaboration, and effective communication set top performers apart in this innovative environment. These skills are crucial for advancing research, fostering teamwork, and driving successful development of new plant varieties.

What are some typical challenges faced when working as a scientist at Pairwise, and how does the team support overcoming them?

Scientists at Pairwise often work on groundbreaking projects involving gene editing and plant biology, which can present challenges such as troubleshooting complex experiments and adapting to rapidly evolving technologies. Collaboration is highly encouraged, with team members regularly sharing insights and resources to solve problems together. The company fosters a supportive environment with cross-functional teams, mentorship opportunities, and access to state-of-the-art tools, helping individuals grow their skills while addressing scientific hurdles.

What is the difference between Pairwise vs Data Analyst?

AspectPairwiseData Analyst
Required CredentialsTypically a background in mathematics, statistics, or computer scienceBachelor's degree in data science, statistics, or related field
Work EnvironmentOften in tech, finance, or research settings focusing on algorithm developmentBusiness, marketing, or finance sectors analyzing data for insights
Employer & Industry UsageUsed in machine learning, AI, and software development companiesCommon in corporate, healthcare, and government agencies
Search & Comparison IntentPeople looking for technical roles involving pairwise data comparisons or algorithmsIndividuals seeking roles in data analysis, reporting, and visualization

Pairwise roles focus on algorithms and comparisons between data points, often requiring programming and statistical skills. Data Analysts interpret data to inform business decisions. While both work with data, Pairwise is more technical and algorithm-driven, whereas Data Analysts focus on insights and reporting.

What does Pairwise do?

Pairwise is a company that develops software tools for the pharmaceutical industry, focusing on optimizing drug combination therapies and analyzing biological data. Employees in related roles often work with data analysis, bioinformatics, and programming skills to support research and development efforts.
More about Pairwise jobs

What cities are hiring for Pairwise jobs?

Cities with the most Pairwise job openings:

What states have the most Pairwise jobs?

States with the most job openings for Pairwise jobs include:

Infographic showing various Pairwise job openings in the United States as of August 2026, with employment types broken down into 89% Full Time, 3% Part Time, 3% Temporary, and 5% Contract. Highlights an 54% Physical, and 46% Remote job distribution, with an average salary of $75,617 per year, or $36.4 per hour.

$117K - $140K/yr

Full-time

Medical, Dental, Vision, PTO

Posted 27 days ago


Job description

ABOUT DEFCON AI

RESILIENCE IN THE FACE OF DISRUPTION. DEFCON AI is an insights company that leverages artificial intelligence, mathematical optimization, data analytics, and software engineering for resilient optimization of complex systems.
In today's dynamically changing world, DEFCON AI's technology aligns outcomes with operational goals, better decision making, and empowers customers to anticipate assess, and mitigate the impacts of disruptions.

About the Role 

As a Data & ML Engineer you will build the data and model layer behind an AI-enabled decision-support system operating inside an accredited environment. That work covers ingestion from many source systems, resolution of incoming records against a shared data model, relevance scoring, and generation of explanations a user can act on and defend.

Three characteristics make this a substantial technical challenge. The incoming data is predominantly low-signal, which means a model can report strong overall accuracy while failing on the cases that matter most. Every output must remain traceable to the underlying sources, because a person downstream is accountable for the result. Record matching is probabilistic rather than exact, so false matches and missed matches both carry meaningful cost.

You will not be starting from an empty repository. We operate an established platform for source custody, extraction, and retrieval, and its architect is a member of this team, so existing design decisions are documented and accessible. Your work will focus on new capability rather than maintenance: record matching, calibrated scoring, and grounded generation, hardened for the target environment. We build with current tooling and expect the same, including the use of AI assistance in our own engineering practice.

This is a fully remote role with occasional travel (up to 25%) to DEFCON AI HQ, customer sites, and vendor facilities as required.

Key Responsibilities 

The technical work falls into four areas. Deep expertise in all four is not expected, so please indicate where your depth lies when you apply. The engineering standards that follow apply to everyone on the team.

Data Modeling and Record Matching

  • Design and maintain the graph of entities, records, and the typed relationships between them
  • Implement probabilistic matching, including blocking, candidate generation, pairwise scoring, clustering, and threshold policy
  • Build deduplication and known-record suppression
  • Establish provenance so that every node and edge traces to the source that asserted it
  • Produce interface and data-flow design documentation detailed enough to serve as an implementation reference for other engineers

Scoring and Calibration

  • Develop relevance and priority models over large, imperfect record sets
  • Own calibration and threshold design, establishing what a score means rather than only how it ranks
  • Design abstention policy that routes uncertain and high-risk cases to a person rather than returning a confident answer
  • Perform feature engineering, establish baselines before introducing complex models, and conduct error analysis that accounts for the differing cost of false positives and false negatives

Retrieval and Generation

  • Implement embeddings, vector storage, and retrieval across a large provenance-tracked evidence base
  • Integrate language models through an approved managed service, and maintain a self-hosted or open-weight alternative within the same boundary
  • Design prompts and output schemas
  • Bind generated text to cited source records, and treat "insufficient evidence" as a valid system response rather than forcing a conclusion
  • Own model packaging, serving, versioning, and rollback

Pipelines and Source Handling

  • Build secure ingestion, transformation, validation, and publishing across structured, semi-structured, and unstructured sources
  • Implement quality checks, schema validation, lineage capture, and audit logging
  • Establish source drift detection so that degradation is surfaced rather than carried into the analysis
  • Generate statistically representative synthetic data so that development can proceed ahead of live data access

Engineering Standards

  • Work to the data model and standards set by the Data Lead, who approves designs and owns them through customer review
  • Document assumptions, caveats, transformation logic, and known limitations, since deliverables are formally reviewed
  • Instrument telemetry so that measurement does not require manual reconstruction
  • Maintain the audit trail covering recommendations, human overrides, and model versions
  • Submit model and pipeline changes through a gated release process rather than deploying in place

Required Qualifications

  • 5+ years of experience in data engineering, data architecture, applied machine learning, ML engineering, or production analytics engineering
  • Strong Python and SQL, with demonstrated experience working with large, imperfect operational data
  • Experience delivering systems for sustained operational use rather than exploratory analysis alone
  • Routine use of AI-assisted development, with informed judgment about where it adds value and where its output requires verification
  • Ability to explain a technical decision to a stakeholder who must defend that decision without understanding its internals
  • US Citizenship Required
  • Active US Secret clearance. The work is performed in a controlled government cloud environment and requires a favorable investigation and CAC eligibility from the start
  • Elevated personnel security requirements apply to portions of this work and are discussed during screening
  • Willingness to travel up to 25% to customer sites, DEFCON AI HQ, and vendor facilities as required

Preferred Qualifications

  • Clearance: active Top Secret
  • Matching: direct experience applying probabilistic matching to inconsistent identity data, including names, dates, addresses, and identifiers, and familiarity with the failure modes of each. Record linkage, master data management, or identity management. Graph data modeling. PostgreSQL and pgvector or comparable. Graph algorithms applied in production
  • Modeling: model calibration and threshold design. Cost-sensitive learning where error types carry unequal consequences. scikit-learn, XGBoost, PyTorch
  • Retrieval and generation: retrieval-augmented generation in production. Prompt and output-schema design. Establishing that generated output remains grounded in its sources, and testing to confirm it. Self-hosted or open-weight model operation. Fine-tuning, adapters, or custom embeddings
  • Pipelines: AWS Glue, Airflow, dbt, Spark, Kafka, or NiFi. Unstructured and semi-structured document ingestion. Synthetic or representative test data generation
  • Environment: federal DevSecOps, RMF, ATO, or DoW cloud environments. Hardened base images. Experience advancing a pipeline from development through accreditation and deployment
  • Domain: sensitive federal or defense data, and work performed under privacy or comparable handling constraints
  • Responsible AI: documentation, model cards, fairness testing, and model monitoring. NIST AI RMF or comparable practice

What Success Looks Like

  • A data model that the rest of the team builds on without needing to redesign it
  • Matching decisions that can be explained and defended to a non-technical reviewer
  • Models whose miss rate is characterized, not only their overall accuracy
  • Generated explanations that assert no more than the sources support, with the citation path intact
  • Pipelines that surface problems early and trace them to a specific source
  • Consistent development progress, including during periods when live data is not yet available

What We Offer: 

  • A fully remote, results-based environment
  • Competitive salary, bonus, and equity package
  • 100% employer paid, comprehensive health insurance including medical, dental, and vision for you and your family
  • Unlimited PTO, with your manager's approval
  • Flexible work environment where you manage your work day
  • 14 weeks of fully-paid parental leave

Salary Range: $150,000-$200,000. This represents the typical salary range for this position based on experience, skills, and other factors.