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Operations Manager Startup Jobs in Massachusetts

Jade Biosciences

$135K - $155K/yr

  • Medical

  • Retirement

Role Overview As a growing startup company, Jade is looking for a hands-on Manager, HR Operations to build scalable processes and partner with our teams to enable Jade's great culture. The Manager, H ...

the 'Quin House

General Manager

Boston, MA · On-site

$105 - $110/hr

Startup/opening of luxury hotel/restaurant experience preferred * Service oriented style with ... Fill in where needed to ensure guest service standards and efficient operations * Continually ...

The 'Quin House

General Manager

Boston, MA · On-site

$105K - $110K/yr

Fill in where needed to ensure guest service standards and efficient operations * Continually ... Startup/opening of luxury hotel/restaurant experience preferred * Service oriented style with ...

envelio

IT Operations & Security Manager

Boston, MA · On-site

$110K - $135K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

About Us envelio Inc. is a fast-growing software startup revolutionizing the utility industry. We ... You'll also oversee IT operations, including device management, identity and access management ...

envelio

IT Operations & Security Manager

Boston, MA · On-site +1

$110K - $135K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

About Us envelio Inc. is a fast-growing software startup revolutionizing the utility industry. We ... You'll also oversee IT operations, including device management, identity and access management ...

Amazon

Program Manager, Quick Commerce Startup Launch

Boston, MA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

... operations, supply chain, and technology teams during the startup phase -Manage critical path ... milestones including permitting, vendor mobilization, equipment installation, and operational ...

BioLabs

Lab Operations Associate

Watertown, MA · On-site

$46K - $70K/yr

... startup companies in their most formative years, while developing your own laboratory operations skills in a cutting-edge biotechnology facility. RESPONSIBILITIES * Assist and support the management ...

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Showing results 21-40

All JobsOperations Startup JobsOperations Manager Startup JobsOperations Manager Startup Jobs in Massachusetts

Operations Manager Startup information

See Massachusetts salary details

$33.9K

$69.3K

$129.4K

How much do operations manager startup jobs pay per year?

As of Aug 16, 2026, the average yearly pay for operations manager startup in Massachusetts is $69,302.00, according to ZipRecruiter salary data. Most workers in this role earn between $44,800.00 and $84,600.00 per year, depending on experience, location, and employer.

What are some common challenges faced by operations managers in a startup environment?

Operations Managers in startups often face rapid changes in priorities, limited resources, and the need to build processes from the ground up. You may find yourself wearing multiple hats, adapting quickly to evolving business requirements, and problem-solving on the fly. Collaboration with founders and cross-functional teams is frequent, requiring strong relationship-building and negotiation skills. Embracing uncertainty and maintaining flexibility are key to thriving in this dynamic and rewarding role.

What is an operations manager startup?

An Operations Manager in a startup oversees daily operations, ensuring efficient processes across different departments. They manage logistics, improve workflows, and implement systems to support scaling. This role requires adaptability, problem-solving, and cross-functional collaboration to streamline operations in a fast-paced environment.

What are the key skills and qualifications needed to thrive as an operations manager startup?

Success as an Operations Manager in a startup requires strong organizational, analytical, and project management skills, often supported by a degree in business or a related field. Familiarity with productivity tools like Asana, Trello, and Google Workspace, as well as experience with ERP or CRM systems, is highly valuable. Outstanding adaptability, leadership, and communication skills help candidates excel in this fast-moving and often ambiguous environment. These abilities are vital to drive operational efficiency, coordinate across departments, and support rapid company growth.

What are popular job titles related to Operations Manager Startup jobs in Massachusetts?

For Operations Manager Startup jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Operations Manager Startup jobs in Massachusetts look for?

The top searched job categories for Operations Manager Startup jobs in Massachusetts are:

What cities in Massachusetts are hiring for Operations Manager Startup jobs?

Cities in Massachusetts with the most Operations Manager Startup job openings:

Operations Manager Startup jobs near you
Infographic showing various Operations Manager Startup job openings in Massachusetts as of August 2026, with employment types broken down into 87% Full Time, 10% Part Time, 1% Temporary, and 2% Contract. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $69,302 per year, or $33.3 per hour.

Manager, HR Operations

Jade Biosciences

On-site, Remote

$135K - $155K/yr

Full-time

Medical, Retirement

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

About Jade Biosciences
Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade's lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade's pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.
Role Overview
As a growing startup company, Jade is looking for a hands-on Manager, HR Operations to build scalable processes and partner with our teams to enable Jade's great culture. The Manager, HR Operations will lead and optimize HR processes, systems, benefits administration, and employee lifecycle operations. This individual will lead the efficient delivery of HR services while ensuring streamlined and compliant processes and amazing employee experiences. The Manager, HR Operations will partner closely with Payroll, Finance, IT, and business leaders to support Jade's teams and growth.
Key Responsibilities
Benefits Administration
  • Oversee administration of health and welfare benefits, retirement plans and leave programs
  • Manage new hire, annual open enrollment and employee benefit communications
  • Partner with brokers and vendors to ensure effective program administration
  • Monitor benefits compliance, audits, and reporting requirements
  • Support benefits strategy by analyzing utilization, trends, and costs

Payroll & Employee Lifecycle Support
  • Collaborate with Payroll to ensure accurate employee data and timely processing
  • Oversee onboarding, offboarding, employee status changes, and record management
  • Manage HR documentation and personnel file administration
  • Ensure seamless end-to-end employee experiences

HR Operations
  • Lead the day-to-day administration and execution of HR operations
  • Develop, implement, and streamline HR processes, policies, and procedures
  • Manage HR operational projects and initiatives from planning through implementation
  • Ensure compliance with federal, state, and provincial employment laws and regulations in the US and Canada
  • Maintain HR policies, procedures, and employee records in accordance with legal requirements
  • Stay informed of employment law changes and recommend process updates as needed
  • Partner with Legal and Finance on compliance-related initiatives

HR Systems and Data Management
  • Lead the administration of HR systems and ensure the accuracy, integrity, and security of employee data
  • Manage system configurations, workflows, security roles, reporting, and integrations
  • Lead HR systems enhancements and implementation projects
  • Develop dashboards and reports to support decision making
  • Partner with Payroll and IT to ensure seamless system functionality

Qualifications
  • Bachelor's degree and 5-8 years of HR experience with 3+ years of progressive benefits, HR systems, and compliance experience required
  • Experience in startup, high-growth organizations required, biotechnology experience preferred
  • Experience administering benefits, HR systems and HR processes in a fast paced, growing organization
  • Experience supporting US multi-state employee populations required, experience supporting Canadian employees preferred
  • Strong knowledge of HR operations, benefits administration, and employment law
  • Advanced HR systems and technology expertise including experience with HRIS platforms such as Paylocity
  • Strong analytical and project management skills
  • Strong attention to detail and commitment to data accuracy
  • Ability to manage multiple priorities, competing deadlines and meet those deadlines
  • Strong communication skills

This is a remote role; periodic travel to team and company events is required.
The anticipated salary range for candidates for this role is $135,000 - $155,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.
As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.
Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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