... Nextflow, Snakemake) and applying sound data organization and metadata practices • Demonstrated ability to champion cross-functional efforts in close collaboration with experimental scientists ...
... Nextflow, Snakemake) and applying sound data organization and metadata practices • Demonstrated ability to champion cross-functional efforts in close collaboration with experimental scientists ...
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required.Sequencing Data:
Quick apply
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required.Sequencing Data:
Senior Scientist I, Data Science (Cambridge)
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well‑documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices. * Demonstrated ability to champion ...
Senior Scientist I, Data Science (Cambridge)
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well‑documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices. * Demonstrated ability to champion ...
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Bioinformatics Scientist
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required. * Sequencing Data:
Senior Scientist I, Data Science (Cambridge)
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well‑documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices. * Demonstrated ability to champion ...
Senior Scientist I, Data Science (Cambridge)
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well‑documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices. * Demonstrated ability to champion ...
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required.Sequencing Data:
Quick apply
Bioinformatics Scientist
Boston, MA · On-site
$170K - $190K/yr
Significant, hands-on experience with Nextflow and Docker is critical for pipeline development. Proficiency with standard bioinformatics tooling (Python, Linux, Git) is required.Sequencing Data:
Senior Scientist I, Data Science
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices * Demonstrated ability to champion cross ...
Senior Scientist I, Data Science
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices * Demonstrated ability to champion cross ...
Senior Bioinformatics Scientist
Boston, MA · On-site
$140 - $200/hr
Nextflow or Snakemake), containers, and version control. * Experience applying state-of-the-art large language models (LLMs) to bioinformatics projects. * Excellent organizational and documentation ...
Senior Bioinformatics Scientist
Boston, MA · On-site
$140 - $200/hr
Nextflow or Snakemake), containers, and version control. * Experience applying state-of-the-art large language models (LLMs) to bioinformatics projects. * Excellent organizational and documentation ...
Senior Bioinformatics Scientist
Boston, MA · On-site
$150 - $210/hr
Nextflow or Snakemake), containers, and version control. * Experience applying state‑of‑the‑art large language models (LLMs) to bioinformatics projects. * Excellent organizational and ...
Senior Bioinformatics Scientist
Boston, MA · On-site
$150 - $210/hr
Nextflow or Snakemake), containers, and version control. * Experience applying state‑of‑the‑art large language models (LLMs) to bioinformatics projects. * Excellent organizational and ...
Senior Scientist I, Data Science
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices * Demonstrated ability to champion cross ...
Senior Scientist I, Data Science
Cambridge, MA · On-site
$130K - $170K/yr
Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices * Demonstrated ability to champion cross ...
Bioinformatics Leader
Boston, MA · On-site
$200K - $229K/yr
Deep, hands-on proficiency in bioinformatics tools and programming languages (e.g., Python, R, Nextflow, Snakemake) and experience with cloud-based compute environments * Domain expertise in at least ...
Bioinformatics Leader
Boston, MA · On-site
$200K - $229K/yr
Deep, hands-on proficiency in bioinformatics tools and programming languages (e.g., Python, R, Nextflow, Snakemake) and experience with cloud-based compute environments * Domain expertise in at least ...
Associate Director, Translational Data Science, Hematology R&D
Medical
Dental
Vision
Retirement
PTO
Proficiency with scalable and cloud-based analytics (e.g., AWS, GCP, or Azure), workflow orchestration (e.g., Nextflow, Snakemake, Airflow), and containerization (Docker). * Familiarity with data ...
New
Associate Director, Translational Data Science, Hematology R&D
Medical
Dental
Vision
Retirement
PTO
Proficiency with scalable and cloud-based analytics (e.g., AWS, GCP, or Azure), workflow orchestration (e.g., Nextflow, Snakemake, Airflow), and containerization (Docker). * Familiarity with data ...
New
Principal Software Engineer - GATK
Cambridge, MA · On-site
$150K - $210K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Experience writing, testing, and deploying bioinformatics workflows in WDL or NextFlow. * Deep working knowledge of genomics/bioinformatics: sequencing data and core file formats (BAM/CRAM/VCF/BCF ...
Principal Software Engineer - GATK
Cambridge, MA · On-site
$150K - $210K/yr
Medical
Dental
Vision
Life
Retirement
PTO
Experience writing, testing, and deploying bioinformatics workflows in WDL or NextFlow. * Deep working knowledge of genomics/bioinformatics: sequencing data and core file formats (BAM/CRAM/VCF/BCF ...
Familiarity with Git-based development, Agile practices, bioinformatics workflow tools such as Cromwell or Nextflow, and AI-assisted coding tools is preferred, along with a strong interest in ...
Familiarity with Git-based development, Agile practices, bioinformatics workflow tools such as Cromwell or Nextflow, and AI-assisted coding tools is preferred, along with a strong interest in ...
Associate Director, Translational Data Science, Hematology R&D
Waltham, MA · On-site
Medical
Dental
Vision
Retirement
PTO
Proficiency with scalable and cloud-based analytics (e.g., AWS, GCP, or Azure), workflow orchestration (e.g., Nextflow, Snakemake, Airflow), and containerization (Docker). * Familiarity with data ...
New
Associate Director, Translational Data Science, Hematology R&D
Waltham, MA · On-site
Medical
Dental
Vision
Retirement
PTO
Proficiency with scalable and cloud-based analytics (e.g., AWS, GCP, or Azure), workflow orchestration (e.g., Nextflow, Snakemake, Airflow), and containerization (Docker). * Familiarity with data ...
New
Bioinformatics Software Engineer
Boston, MA · On-site
$112K - $132K/yr
Familiarity with Git-based development, Agile practices, bioinformatics workflow tools such as Cromwell or Nextflow, and AI-assisted coding tools is preferred, along with a strong interest in ...
Bioinformatics Software Engineer
Boston, MA · On-site
$112K - $132K/yr
Familiarity with Git-based development, Agile practices, bioinformatics workflow tools such as Cromwell or Nextflow, and AI-assisted coding tools is preferred, along with a strong interest in ...
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Full-time
Re-posted 18 days ago
Job description
Job Summary:
Sail Biomedicines is building a new class of fully programmable medicines by integrating circular RNA (eRNA™), targeted nanoparticle delivery, and advanced computational approaches. The Senior Scientist I will operate at the interface of platform and program, applying data-driven approaches to analyze preclinical datasets and support therapeutic development efforts.
Responsibilities:
• Perform in-depth analysis of preclinical and platform datasets, including immunophenotyping, functional assays, and multi-omics data to support both therapeutic programs and platform development
• Integrate and interpret data across studies and contexts to generate biological insights that inform CAR activity, persistence, immune dynamics and platform-level understanding of our therapeutics
• Collaborate closely with immunology and platform teams to inform experimental design and interpret results
• Work resourcefully with internal/external datasets to contextualize findings and strengthen conclusions
• Apply statistical and systems modeling to develop deeper understanding of product and platform attributes and performance.
• Apply and promote best practices in data structuring, annotation, and metadata usage to enable reliable, scalable and reusable downstream analysis across programs and platform efforts
• Develop and maintain reproducible analysis workflows, with clear documentation and version control (Git) and contribute to a well-organized data environment by following FAIR-aligned practices in day-to-day work
• Communicate findings clearly with collaborators through visualizations, presentations, and written summaries
Qualifications:
Required:
• Ph.D. in Computational Biology, Bioinformatics, Systems Biology, Biophysics or related field
• 3+ years of experience analyzing multifaceted biological datasets in biotech, pharma, or academia
• Firsthand experience working in CAR-T or RNA therapeutics.
• Demonstrated experience applying modeling (statistical, system) to biological data.
• Strong expertise in high-dimensional data analysis (e.g., RNA-seq, single-cell, in vivo studies) with the ability to transform raw data to refined downstream biological interpretations
• Proficiency in Python and/or R, with strong data analysis and visualization skills and a firm grasp of modern statistics (mixed models, Bayesian methods, etc.)
• Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices
• Demonstrated ability to champion cross-functional efforts in close collaboration with experimental scientists, taking ownership and driving insights even in areas outside your core subject matter expertise
Preferred:
• Computational design of Antibody/VHH/scFv/CAR proteins
• Experience in immunology, cell therapy, or CAR biology, particularly in vivo systems
• Experience integrating complex datasets and cross-study meta-analysis
• Exposure to cloud-based or collaborative data environments
• Track record of impactful scientific contributions (publications or program support)
Company:
Sail Biomedicines is a flagship pioneering company that is developing tomorrow's medicines today using life's language. Founded in 2023, the company is headquartered in Somerville, USA, with a team of 51-200 employees. The company is currently Growth Stage.
Sail Biomedicines is building a new class of fully programmable medicines by integrating circular RNA (eRNA™), targeted nanoparticle delivery, and advanced computational approaches. The Senior Scientist I will operate at the interface of platform and program, applying data-driven approaches to analyze preclinical datasets and support therapeutic development efforts.
Responsibilities:
• Perform in-depth analysis of preclinical and platform datasets, including immunophenotyping, functional assays, and multi-omics data to support both therapeutic programs and platform development
• Integrate and interpret data across studies and contexts to generate biological insights that inform CAR activity, persistence, immune dynamics and platform-level understanding of our therapeutics
• Collaborate closely with immunology and platform teams to inform experimental design and interpret results
• Work resourcefully with internal/external datasets to contextualize findings and strengthen conclusions
• Apply statistical and systems modeling to develop deeper understanding of product and platform attributes and performance.
• Apply and promote best practices in data structuring, annotation, and metadata usage to enable reliable, scalable and reusable downstream analysis across programs and platform efforts
• Develop and maintain reproducible analysis workflows, with clear documentation and version control (Git) and contribute to a well-organized data environment by following FAIR-aligned practices in day-to-day work
• Communicate findings clearly with collaborators through visualizations, presentations, and written summaries
Qualifications:
Required:
• Ph.D. in Computational Biology, Bioinformatics, Systems Biology, Biophysics or related field
• 3+ years of experience analyzing multifaceted biological datasets in biotech, pharma, or academia
• Firsthand experience working in CAR-T or RNA therapeutics.
• Demonstrated experience applying modeling (statistical, system) to biological data.
• Strong expertise in high-dimensional data analysis (e.g., RNA-seq, single-cell, in vivo studies) with the ability to transform raw data to refined downstream biological interpretations
• Proficiency in Python and/or R, with strong data analysis and visualization skills and a firm grasp of modern statistics (mixed models, Bayesian methods, etc.)
• Experience building reproducible and well-documented analysis workflows (Nextflow, Snakemake) and applying sound data organization and metadata practices
• Demonstrated ability to champion cross-functional efforts in close collaboration with experimental scientists, taking ownership and driving insights even in areas outside your core subject matter expertise
Preferred:
• Computational design of Antibody/VHH/scFv/CAR proteins
• Experience in immunology, cell therapy, or CAR biology, particularly in vivo systems
• Experience integrating complex datasets and cross-study meta-analysis
• Exposure to cloud-based or collaborative data environments
• Track record of impactful scientific contributions (publications or program support)
Company:
Sail Biomedicines is a flagship pioneering company that is developing tomorrow's medicines today using life's language. Founded in 2023, the company is headquartered in Somerville, USA, with a team of 51-200 employees. The company is currently Growth Stage.