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Next Generation Sequencing Scientist Jobs (NOW HIRING)

Aequor

Bioinformatics Scientist

Tucson, AZ · On-site

$45 - $63/hr

Job Title : Bioinformatics Scientist Location : Tucson, AZ 85755 (hybrid) Duration : 36 months ... hands-on familiarity with next-generation sequencing (NGS) laboratory processes. * You are ...

GeneDx, Inc

Senior Clinical Scientist

Gaithersburg, MD · On-site

... next generation sequencing panels. To learn more about GeneDx, please visit our website at www ... Senior Clinical Scientist Whole Exome Sequencing Program (WES) GeneDx, Inc Gaithersburg, MD MD/PhD ...

Tempus

Molecular Technologist I-III

Triangle, VA · On-site

Perform next-generation sequencing, including nucleic acid extraction, DNA/RNA quantification and ... MS in medical technology, clinical laboratory science, chemical, physical or biological science and ...

Tempus

Molecular Technologist I-III

Triangle, VA · On-site

Perform next-generation sequencing, including nucleic acid extraction, DNA/RNA quantification and ... MS in medical technology, clinical laboratory science, chemical, physical or biological science and ...

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How much do next generation sequencing scientist jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for next generation sequencing scientist in the United States is $38.64, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $50.00 per hour, depending on experience, location, and employer.

What is a next generation sequencing scientist?

A Next Generation Sequencing (NGS) Scientist is responsible for designing, optimizing, and executing NGS experiments to analyze genetic material. They work with DNA and RNA sequencing technologies to generate and interpret high-throughput sequencing data. Their role includes sample preparation, library construction, sequencing, and bioinformatics analysis. NGS Scientists often collaborate with researchers, clinicians, and biologists to apply sequencing data in fields such as medicine, agriculture, and biotechnology. Strong knowledge of molecular biology, data analysis, and sequencing platforms like Illumina or PacBio is essential for this role.

What does a next generation sequencing scientist do?

A Next Generation Sequencing Scientist is responsible for designing and executing sequencing experiments, preparing libraries, running NGS instruments, and conducting data quality control and analysis. Daily tasks often include troubleshooting protocols, optimizing workflows, and interpreting complex genomic data using bioinformatics tools. They also collaborate closely with other scientists, bioinformaticians, and laboratory staff to achieve project goals and may contribute to presentations, reports, or publications based on their findings. This role offers the opportunity to work on a range of projects, from clinical diagnostics to cutting-edge research in genetics and biotechnology.

What are the key skills and qualifications needed to thrive as a next generation sequencing scientist?

A Next Generation Sequencing (NGS) Scientist typically requires strong expertise in molecular biology, genomics, data analysis, and a relevant advanced degree such as a PhD or MS in a life science field. Experience with NGS platforms (like Illumina, PacBio, or Oxford Nanopore), bioinformatics tools, and laboratory automation systems is highly valuable. Strong problem-solving skills, effective teamwork, and clear scientific communication make candidates stand out. These skills are essential for delivering accurate genomic analyses, driving research progress, and ensuring high-quality results in a fast-paced, collaborative laboratory setting.

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Next Generation Sequencing Scientist jobs near you
Infographic showing various Next Generation Sequencing Scientist job openings in the United States as of August 2026, with employment types broken down into 50% Full Time, and 50% Contract. Highlights an 100% In-person job distribution, with an average salary of $80,367 per year, or $38.6 per hour.

Senior Scientist, Antibody Repertoire Sequencing & Discovery

AbbVie

Worcester, MA • On-site

$109K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 19 days ago

AbbVie rating

8.7

Company rating: 8.7 out of 10

Based on 103 frontline employees who took The Breakroom Quiz

14th of 86 rated pharmaceutical

Job description

Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
The Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated Senior Scientist to join the Molecular Core team at AbbVie Bioresearch Center (ABC). The ABC site in Worcester, MA, offers a unique setting where Biotherapeutics discovery, development and manufacturing coexist in one location. The Molecular Core partners with multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative approaches for antibody discovery including in vivo technologies, custom immunization strategies, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets.
As a member of the in vivo antibody discovery group, you will be responsible for optimizing and expanding antibody repertoire sequencing capabilities in antibody discovery, as well as developing innovative methods to help maintain AbbVie's industry-leading standards. The successful candidate will generate original technical ideas and research strategies for antibody repertoire sequencing (RepSeq) and analysis. They will have technical expertise in generating and applying RepSeq data to therapeutic antibody discovery including computational proficiency enabling highly effective collaboration with computational scientists. This is an exciting opportunity to help drive antibody discovery programs within a multidisciplinary research group in a dynamic, fast-paced environment.
Responsibilities:
  • Act as scientific and technical expert in antibody repertoire sequencing (RepSeq/AIRR-Seq/BCR-Seq) for therapeutic antibody discovery and hit expansion - Bulk sequencing, 10X, and other commercial and proprietary platforms.
  • Collaborate with computational scientists to optimize repertoire analysis and open new avenues for antibody discovery through repertoire guided machine learning and generative design
  • Generate, document, and archive repertoire data with appropriate context and metadata to support broader team access and future utilization.
  • Analyze and interpret results, placing data in proper scientific context through review of relevant literature, and present findings at team meetings.
  • Regularly present data, communicate effectively, and coordinate work within a highly matrixed project team environment.
  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced, multidisciplinary environment.
  • Exhibit a can-do attitude and strong interpersonal and communication skills when working across multiple functional teams.

Qualifications
  • BS, MS, or PhD in immunology, molecular biology, biochemistry, bioinformatics or a related field with typically 0-4+ (PhD), 8-10+ (MS), or 10-12+ (BS) years of relevant experience
  • Extensive scientific expertise in immunoglobulin genetics and antibody biology; specifically, the candidate should be well versed in antibody diversity generation (germline genes / V(D)J recombination / somatic hypermutation), affinity maturation, and B cell biology.
  • Extensive technical expertise in the isolation and molecular biology of antibody variable region genes for Next-generation Sequencing (NGS) and the capture of RepSeq/AIRR-Seq/BCR-Seq) data; both for single-chain and paired heavy- and light-chain recovery
  • Understanding of NGS technologies and platforms - Illumina (NextSeq, MiSeq) and PacBio
  • Understanding and proficiency in molecular biology techniques (e.g. PCR, primer design, molecular cloning, Gibson Assembly, plasmid design)
  • Ability to improve and streamline existing processes
  • Strong attention to quality and details when exercising organizational, documentation and communication skills
  • Proven flexibility to deal with changing timelines and shifting work priorities
  • Competency with software programs, including antibody analysis (PipeBio), DNA analysis (Geneious, Sequencher) and MS Office (Excel, PowerPoint, Word)
  • Fluency in computational science and familiarity with the application of predictive AI/ML tools and protein language models (PLMs) for antibody discovery

Desirable:
  • Experience in non-human and non-murine immunogenetics
  • Prior experience with bioinformatics and computational analysis of large DNA and protein data sets is highly desired
  • Experience with repertoire sequencing from in vitro antibody discovery libraries
  • Experience with mammalian cell culture, aseptic technique, and transient transfection
  • Experience in immunoassays using techniques like ELISA and flow cytometry

Position will be filled at level commensurate with extent of education, experience, and accomplishment - Senior Scientist I or Senior Scientist II
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive program.
  • This job may be eligible to participate in our long-term incentive program.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html

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About AbbVie

Sourced by ZipRecruiter

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

North Chicago, IL, US

Year founded

2013

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