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$80.7K

$103.5K

How much do molecular cloning jobs pay per year?

As of Aug 12, 2026, the average yearly pay for molecular cloning in the United States is $80,687.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,000.00 and $98,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in molecular cloning?

Success in Molecular Cloning requires a deep understanding of molecular biology techniques, DNA manipulation, and gene expression, typically supported by a relevant degree in biology, biochemistry, or a related field. Familiarity with laboratory equipment such as PCR machines, gel electrophoresis apparatus, and software for sequence analysis is essential, along with adherence to biosafety protocols. Effective troubleshooting abilities, attention to detail, and strong teamwork and communication skills are important soft skills in this role. These skills ensure the accurate construction and analysis of recombinant DNA, driving successful project outcomes in research and biotechnology settings.

What does someone working in molecular cloning do?

Professionals in molecular cloning generally spend their days designing and executing experiments to construct, amplify, and analyze recombinant DNA, often using techniques like PCR, restriction enzyme digestion, and DNA ligation. They routinely prepare reagents, maintain detailed laboratory records, and analyze experimental data to verify successful cloning. Collaboration is common, as molecular cloning specialists often work closely with research scientists, laboratory technicians, and bioinformaticians to achieve shared research goals. Additionally, maintaining a sterile and organized lab environment is critical to ensure the integrity of experiments and reproducibility of results.

What is molecular cloning?

A Molecular Cloning job involves the process of assembling recombinant DNA molecules and directing their replication within host organisms. Scientists in this role use techniques such as PCR, restriction enzyme digestion, and ligation to insert genetic material into vectors like plasmids. These constructs are then introduced into bacterial, yeast, or mammalian cells to study gene function, produce proteins, or develop genetically modified organisms. Molecular cloning is widely used in research labs, biotechnology, and pharmaceutical industries to advance genetic engineering, drug discovery, and synthetic biology.

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What cities are hiring for Molecular Cloning jobs? Cities with the most Molecular Cloning job openings:
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Molecular Cloning jobs near you
Infographic showing various Molecular Cloning job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 66% Full Time, 31% Part Time, and 2% Contract. Highlights an 67% Physical, 1% Hybrid, and 32% Remote job distribution, with an average salary of $80,687 per year, or $38.8 per hour.

Associate Scientist, Display Technologies

BigHat Biosciences

San Mateo, CA

$120K - $135K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 3 days ago

Job description

The role: BigHat Biosciences is seeking a curious and motivated Associate Scientist to join the Display Technologies team. This individual will contribute to BigHat's antibody discovery and engineering efforts and help generate high-quality data to improve BigHat's machine learning models using display technologies, working closely with senior scientists and cross-functional teams.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate. 
  • Support R&D projects advancing display technologies at BigHat that expands BigHat's antibody discovery capabilities and feed its ML models.
  • Lead in the construction and QC of phage and yeast display libraries across diverse antibody formats (VHH, scFv, Fab) using standard molecular biology techniques (PCR, molecular cloning, electroporation).
  • Execute phage and yeast display selections using naive and affinity and stability maturation libraries to discover and engineer antibodies with desired therapeutic properties.
  • Express, purify, and characterize display-derived molecules using assays including ELISA, flow cytometry, BLI/SPR, CE-SDS, and others.
  • Analyze selection results and contribute to discussions on next steps and future experimental design.
  • Collaborate with BigHat's Data Science and Machine Learning teams to inform library design and interpret selection data for model training.
  • Present experimental plans and results during regular meetings with manager and science teams.
  • Maintain thorough records using LIMS and electronic notebooks.
  • BS or MS in Biochemistry, Molecular Biology, Bioengineering, or a related field.
  • 4+ years of hands-on laboratory experience (academic or industry); relevant internship or research experience welcome.
  • Familiarity with general molecular biology techniques (PCR, molecular cloning, gel electrophoresis).
  • Exposure to antibody biology, display technologies (phage or yeast), and protein expression.
  • Demonstrated ability to follow protocols carefully, troubleshoot experiments, and maintain detailed lab records.
  • Effective time management and clear written and verbal communication skills.
  • Collaborative, team-oriented mindset with an eagerness to learn in a fast-paced startup environment.
  • Nice-to-haves include experience with flow cytometry, ELISA, or other binding assays, and familiarity with NGS or automation platforms.
The salary estimated for this position is $120,000 - $135,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match 
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

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