ZipRecruiter

Log In

1

Modeling Simulation Analyst Jobs in Boston, MA (NOW HIRING)

Vrtx

Executive Director, Modeling & Simulations

Boston, MA · Hybrid

$268K - $402K/yr

... analysis, clinical trial design and simulation, mathematical disease models, mechanistic modeling and analyses of multidimensional data This role will have final approval on providing direction and ...

STR

Lead Modeling and Simulation Engineer

Woburn, MA

$157K - $224K/yr

As a Lead Modeling and Simulation (M&S) Engineer, you will lead teams working a portfolio of ... Work with RF sensor engineering teams to develop system models, conduct performance analyses, and ...

STR

Lead Modeling and Simulation Engineer

Woburn, MA · On-site

$157K - $224K/yr

As a Lead Modeling and Simulation (M&S) Engineer, you will lead teams working a portfolio of ... Work with RF sensor engineering teams to develop system models, conduct performance analyses, and ...

STR

Lead Modeling and Simulation Engineer

Woburn, MA

$157K - $224K/yr

As a Lead Modeling and Simulation (M&S) Engineer, you will lead teams working a portfolio of ... Work with RF sensor engineering teams to develop system models, conduct performance analyses, and ...

STR

Principal Defense Systems Analyst

Woburn, MA

$220K - $260K/yr

The Systems Autonomy, Analysis, and Modeling (SAAM) Group within the Sensors Division uses modeling and simulation to create and analyze system architectures and designs and their mission impact. We ...

STR

Principal Defense Systems Analyst

Woburn, MA · On-site

$220K - $260K/yr

The Systems Autonomy, Analysis, and Modeling (SAAM) Group within the Sensors Division uses modeling and simulation to create and analyze system architectures and designs and their mission impact. We ...

STR

Principal Defense Systems Analyst

Boston, MA

$220K - $260K/yr

The Systems Autonomy, Analysis, and Modeling (SAAM) Group within the Sensors Division uses modeling and simulation to create and analyze system architectures and designs and their mission impact. We ...

next page

Showing results 1-20

All JobsModeling Simulation Analyst JobsModeling Simulation Analyst Jobs in Boston, MA

Modeling Simulation Analyst information

See Boston, MA salary details

$42.4K

$110K

$156.4K

How much do modeling simulation analyst jobs pay per year?

As of Jul 18, 2026, the average yearly pay for modeling simulation analyst in Boston, MA is $110,004.00, according to ZipRecruiter salary data. Most workers in this role earn between $85,300.00 and $140,700.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Modeling Simulation Analyst, and why are they important?

To thrive as a Modeling Simulation Analyst, you need a strong background in mathematics, statistics, and computer science, often supported by a relevant degree such as in engineering or applied mathematics. Proficiency in simulation software (e.g., MATLAB, Simulink, Arena), programming languages (such as Python or C++), and familiarity with data analysis tools are typically required. Strong analytical thinking, attention to detail, and effective communication skills set top candidates apart in this role. These abilities are vital for developing accurate models, interpreting complex data, and clearly presenting findings to support strategic decision-making.

How does a Modeling Simulation Analyst typically collaborate with cross-functional teams during a project?

Modeling Simulation Analysts frequently work alongside engineers, data scientists, and project managers to develop and refine simulation models. Collaboration often involves gathering system requirements, validating model assumptions with subject matter experts, and presenting simulation results to stakeholders. Clear communication is essential, as analysts must translate complex simulation data into actionable insights for decision-makers. Regular team meetings and iterative feedback are common to ensure the models accurately reflect real-world scenarios and project goals.

What are Modeling Simulation Analysts?

Modeling Simulation Analysts are professionals who use mathematical models, simulations, and analytical techniques to study complex systems and predict their behavior. They help organizations make informed decisions by evaluating scenarios, testing hypotheses, and optimizing processes through virtual models. These analysts work in various industries, including defense, healthcare, manufacturing, and transportation, to improve efficiency, reduce costs, and support planning and strategy. Their work often involves collaboration with engineers, scientists, and decision-makers to interpret simulation results and implement solutions.

What is the difference between Modeling Simulation Analyst vs Data Analyst?

AspectModeling Simulation AnalystData Analyst
Required CredentialsBachelor's or master's in engineering, computer science, or related fields; proficiency in simulation softwareBachelor's in statistics, mathematics, or related fields; proficiency in data analysis tools
Work EnvironmentEngineering labs, simulation centers, or technical departmentsOffice settings, data centers, or business environments
Employer & Industry UsageManufacturing, aerospace, defense, or engineering firmsFinance, healthcare, marketing, or business sectors
Common Search & ComparisonYesYes

The Modeling Simulation Analyst focuses on creating and analyzing simulations to predict system behaviors, often requiring engineering or technical expertise. In contrast, Data Analysts interpret data sets to inform business decisions, typically using statistical tools. While both roles involve data handling, the Modeling Simulation Analyst emphasizes modeling complex systems, whereas Data Analysts focus on data interpretation for strategic insights.

What are popular job titles related to Modeling Simulation Analyst jobs in Boston, MA? For Modeling Simulation Analyst jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Modeling Simulation Analyst jobs in Boston, MA look for? The top searched job categories for Modeling Simulation Analyst jobs in Boston, MA are:
What cities near Boston, MA are hiring for Modeling Simulation Analyst jobs? Cities near Boston, MA with the most Modeling Simulation Analyst job openings:
Modeling Simulation Analyst jobs near you

Executive Director, Modeling & Simulations

Vrtx

Boston, MA • Hybrid

$268K - $402K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 26 days ago

Job description

Job Description

General Summary:

The Executive Director, Modeling & Simulations (M&S) manages strategic, scientific and operational aspects of M&S within the Early Clinical Development Department at Vertex. The incumbent is responsible for the implementation of modeling and simulation strategy at Vertex; including but not limited to traditional PK/PD, population PK, exposure-response, model-based meta-analysis, clinical trial design and simulation, mathematical disease models, mechanistic modeling and analyses of multidimensional data This role will have final approval on providing direction and guidance for M&S plans across programs.

Key Duties and Responsibilities:

  • Leading and developing the Modeling & Simulation team
  • Champion the use of modeling and simulation to impact decision making in clinical and exploratory development
  • Manage a group of senior leaders comprised of Senior Directors and Director level employees
  • Provide expert input for internal review of all documents internal and external related to modeling and simulation or M&S derived outputs
  • Represent programs in external partnerships and advisory boards
  • Oversee and contribute to regulatory and safety documents
  • Represent modeling and simulation during face-to-face regulatory interactions
  • Provide management and career development to associate program leads
  • Assist in recruitment and hiring for the M&S group.

Knowledge and Skills:

  • Demonstrated ability to lead teams and manage people
  • Experience designing clinical pharmacology and pharmacometrics components of filing packages and associated clinical studies
  • Regulatory agency interactions including written responses and IND packages
  • End of Phase 2 and NDA/MAA regulatory experience
  • Support of drug development programs in all Phases including life-cycle management
  • Strong experience leading cross-functional teams
  • Academic or clinical post doctoral training with significant publication history
  • Superior communication skills
  • Proactive problem solver and demonstrated ability to work in a matrix environment

Education and Experience:

  • Master's or PhD in Pharmaceutical sciences, Pharmacometrics, mathematics, statistics, or other quantitative discipline with an emphasis on Pharmacometrics and PKPD modeling
  • Typically requires the following: PhD with 20 years or Master's Degree with 25 years' experience in the application of pharmacometric and other modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies
  • Strong management experience

#LI-KM4

Pay Range:

$268,000 - $402,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Apply