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Modeling Simulation Analyst Jobs in Lawrence, MA

Vrtx

Modeling & Simulations Director

Boston, MA · Hybrid

$194K - $291K/yr

This role determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. Key Duties ...

New

Vrtx

Modeling & Simulations Associate Director

Boston, MA · Hybrid

$168K - $252K/yr

This role determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. Key Duties ...

Vrtx

Modeling & Simulations Associate Director

Boston, MA · Hybrid

$168K - $252K/yr

This role determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. Key Duties ...

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Modeling Simulation Analyst information

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$40.9K

$106.2K

$151.1K

How much do modeling simulation analyst jobs pay per year?

As of Aug 21, 2026, the average yearly pay for modeling simulation analyst in Lawrence, MA is $106,230.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,400.00 and $135,900.00 per year, depending on experience, location, and employer.

What is a modeling simulation analyst?

Modeling Simulation Analysts are professionals who use mathematical models, simulations, and analytical techniques to study complex systems and predict their behavior. They help organizations make informed decisions by evaluating scenarios, testing hypotheses, and optimizing processes through virtual models. These analysts work in various industries, including defense, healthcare, manufacturing, and transportation, to improve efficiency, reduce costs, and support planning and strategy. Their work often involves collaboration with engineers, scientists, and decision-makers to interpret simulation results and implement solutions.

How does a modeling simulation analyst typically collaborate with cross-functional teams during a project?

Modeling Simulation Analysts frequently work alongside engineers, data scientists, and project managers to develop and refine simulation models. Collaboration often involves gathering system requirements, validating model assumptions with subject matter experts, and presenting simulation results to stakeholders. Clear communication is essential, as analysts must translate complex simulation data into actionable insights for decision-makers. Regular team meetings and iterative feedback are common to ensure the models accurately reflect real-world scenarios and project goals.

What are the key skills and qualifications needed to thrive as a modeling simulation analyst, and why are they important?

To thrive as a Modeling Simulation Analyst, you need a strong background in mathematics, statistics, and computer science, often supported by a relevant degree such as in engineering or applied mathematics. Proficiency in simulation software (e.g., MATLAB, Simulink, Arena), programming languages (such as Python or C++), and familiarity with data analysis tools are typically required. Strong analytical thinking, attention to detail, and effective communication skills set top candidates apart in this role. These abilities are vital for developing accurate models, interpreting complex data, and clearly presenting findings to support strategic decision-making.

What is the difference between Modeling Simulation Analyst vs Data Analyst?

AspectModeling Simulation AnalystData Analyst
Required CredentialsBachelor's or master's in engineering, computer science, or related fields; proficiency in simulation softwareBachelor's in statistics, mathematics, or related fields; proficiency in data analysis tools
Work EnvironmentEngineering labs, simulation centers, or technical departmentsOffice settings, data centers, or business environments
Employer & Industry UsageManufacturing, aerospace, defense, or engineering firmsFinance, healthcare, marketing, or business sectors
Common Search & ComparisonYesYes

The Modeling Simulation Analyst focuses on creating and analyzing simulations to predict system behaviors, often requiring engineering or technical expertise. In contrast, Data Analysts interpret data sets to inform business decisions, typically using statistical tools. While both roles involve data handling, the Modeling Simulation Analyst emphasizes modeling complex systems, whereas Data Analysts focus on data interpretation for strategic insights.

Is modeling a high paying job?

Modeling simulation analysts often earn competitive salaries, especially with experience and advanced skills in programming, data analysis, and simulation tools. Salaries can vary based on industry, location, and level of expertise, but the role generally offers above-average compensation compared to many entry-level positions.

What does a modeling simulation analyst do?

A modeling simulation analyst develops and runs computer models to analyze complex systems and predict outcomes. They use specialized software and data analysis skills to support decision-making in fields like engineering, defense, or manufacturing, often working with large datasets and simulation tools. The role requires strong analytical skills, attention to detail, and knowledge of modeling techniques and programming languages.

What cities near Lawrence, MA are hiring for Modeling Simulation Analyst jobs?

Cities near Lawrence, MA with the most Modeling Simulation Analyst job openings:

Modeling Simulation Analyst jobs near you
Infographic showing various Modeling Simulation Analyst job openings in Lawrence, MA as of August 2026, with employment types broken down into 85% Full Time, 11% Part Time, and 4% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $106,230 per year, or $51.1 per hour.

Modeling & Simulations Director

Vrtx

Boston, MA • Hybrid

$194K - $291K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted yesterday

New

Job description

Job Description

General Summary:

The Modeling & Simulations Associate Director will be responsible for developing and executing M&S strategies and activities in cross functional drug development project teams in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D organization. This role determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making.

Key Duties and Responsibilities:

  • As Modeling & Simulations (M&S) lead in one or more cross functional drug development teams, responsibilities include the development and execution of Modeling & Simulation plans and analyses fully integrated with the overall development plans
  • By using state of the art Modeling & Simulation methodologies strongly contribute to critical decision making like study design, dose selection, probability of success estimation etc.
  • Independently perform mechanism based PKPD and population PK and PKPD-analyses, Clinical trial simulations and other model based analyses on a regular basis
  • Contribute to the continuous improvement in efficiency and effectiveness of our M&S capability by supporting training activities, evaluating and incorporating new M&S tools as appropriate.

Knowledge and Skills:

  • A specialized understanding of biology, pharmacokinetic and quantitative pharmacology (PKPD) principles.
  • Excellent hands-on skills in population PK and PKPD modeling, mechanistic PKPD modeling, Clinical trial simulations, Disease progression modeling, etc.
  • Excellent skills in the use of NonMem, PsN, R, Phoenix, and similar tools
  • Demonstrated strong leadership-, collaborative and influencing skills
  • Excellent, verbal and written communication skills
  • In-depth experience working in clinical development teams and integrating the use of PK/PD modeling and/or modeling of complex biological system

Education and Experience:

  • Master's or PhD, with preference in Pharmaceutical sciences, Pharmacometrics, mathematics, statistics, or other quantitative discipline with an emphasis on Pharmacometrics and PKPD modeling
  • Typically requires the following: PhD and 10 years or Master's Degree and 15 years experience in the application of pharmacometric and other modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies

Pay Range:

$194,400 - $291,600

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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