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Associate Scientist, Protein Sciences

San Jose, CA · On-site

$115K - $125K/yr

OBT'sOGAP-verify ® platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patienttumors. OGAP is used to identifynovel ...

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How much do membrane protein jobs pay per hour?

As of Jul 28, 2026, the average hourly pay for membrane protein in the United States is $26.43, according to ZipRecruiter salary data. Most workers in this role earn between $18.99 and $31.01 per hour, depending on experience, location, and employer.

What are some common challenges faced by researchers working on membrane protein projects, and how can these be addressed?

Researchers working with membrane proteins often encounter challenges related to protein expression, purification, and structural characterization, as these proteins are typically unstable outside their native lipid environment. Solutions include optimizing expression systems, using detergents or nanodiscs for stabilization, and leveraging advanced methods like cryo-EM for structural studies. Team collaboration with experts in biochemistry, structural biology, and computational modeling can also help overcome technical hurdles and accelerate project progress.

What are membrane proteins?

Membrane proteins are proteins that are part of, or interact with, the biological membranes of cells. They play crucial roles in various cellular processes such as signaling, transport of molecules, and maintaining the structure of the cell. These proteins can be found embedded within the membrane (integral) or attached to the membrane surface (peripheral). Because of their importance in cell function, membrane proteins are often targets for drugs and are studied extensively in biomedical research.

What is the difference between Membrane Protein vs Cell Biologist?

AspectMembrane ProteinCell Biologist
Required CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fields; lab experienceBachelor's or Master's in Cell Biology, Molecular Biology, or related fields; research experience
Work EnvironmentLaboratories focusing on protein isolation, structural analysis, and functional assaysResearch labs studying cell structure, function, and processes
Industry UsagePharmaceutical, biotech, academic researchAcademic, research institutions, biotech

Membrane Protein specialists focus on isolating, characterizing, and understanding proteins embedded in cell membranes, often working with biochemical and structural techniques. Cell Biologists study overall cell functions, including membrane components, but with broader research on cell processes. While both roles require similar educational backgrounds and lab skills, Membrane Protein roles are more specialized in protein analysis, whereas Cell Biologists have a wider focus on cell systems.

What are the key skills and qualifications needed to thrive as a Membrane Protein Scientist, and why are they important?

To thrive as a Membrane Protein Scientist, you need a solid background in biochemistry, molecular biology, and protein chemistry, usually supported by a Ph.D. or relevant research experience. Expertise with techniques like X-ray crystallography, cryo-EM, mass spectrometry, and software for protein modeling is crucial. Strong analytical thinking, attention to detail, and effective communication help you excel in both independent and collaborative research settings. These skills are essential to successfully investigate the structure and function of membrane proteins, which are vital for drug discovery and understanding cellular processes.
More about Membrane Protein jobs
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Membrane Protein jobs near you
Infographic showing various Membrane Protein job openings in the United States as of July 2026, with employment types broken down into 3% As Needed, 77% Full Time, 18% Part Time, and 2% Contract. Highlights an 84% Physical, 1% Hybrid, and 15% Remote job distribution, with an average salary of $54,972 per year, or $26.4 per hour.
Scientist / Membrane Protein Purification

Scientist / Membrane Protein Purification

Pioneer Data Systems Inc

Spring House, PA • On-site

Contractor

Posted 19 days ago

Job description

Position Details: 
Our client, a world-leading Pharmaceutical Company in Spring House, PA is currently looking for a Scientist to join their expanding team.
 
Job Title: Scientist / Membrane Protein Purification
Duration: 12 months contract, extendable up to 24 months 
Location: Spring House, PA
 
Note: 
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
 
Notes:
Role is 100% onsite in Spring House, PA
Bachelor's degree is required
#1 Required skill: Must have processing protein production, purification experience
#2 Required skill: Must have analytical characterization experience
Membrane protein experience, a huge plus
Must have 2-4 years of experience
Will attend group meetings
60%-70% of the role will be lab based work
Will do data capturing
Must have Protein Purification and Production experience
 
Job Description:
Key Responsibilities:
Support membrane protein expression and purification.
Conduct protein production, purification and characterization.
Characterization and quality check of membrane proteins to support biotherapeutics development.
Collaborate effectively in a multi-team environment.
Contribute to both internal and external efforts in membrane protein production.
Qualifications
Education:
Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required.
Experience and Skills:
Required:
Experience with membrane protein expression and optimization, purification, and characterization of proteins
Well-versed with analytical characterization to determine quality, conformation, purity and stability
Knowledge of protein expression construct design and optimization, and expression platforms
Excellent communication skills to collaborate with internal and external partners
Preferred:
Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs
Experience in independently operating AKTA FPLC and analytical HPLC instruments
Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery
Knowledge and experience with CROs for protein production
It’s 40 hour/week full on-site job.