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Medical Safety Director Jobs (NOW HIRING)

Vrtx

Patient Safety Medical Director

Boston, MA · Hybrid

$276K - $414K/yr

The Senior Medical Director, Patient Safety, Disease Area Safety Head (DASH) will lead all safety and benefit-risk related activities for products within the role's Disease-area and/or Franchise ...

Peyton Resource Group

Safety Director

San Antonio, TX · On-site

$90K - $110K/yr

The Safety Director will regularly visit job sites and facilities throughout Texas while ensuring ... Comprehensive medical, dental, and vision insurance. Company-paid life insurance and short- and ...

Construction Execs

Safety Director

Carrollton, GA

$95K - $110K/yr

The Safety Director will collaborate closely with the Safety Manager and will also take on ... Benefits: * Comprehensive Medical, Dental, and Vision Insurance * 401(k) Retirement Plan with ...

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Medical Safety Director information

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How much do medical safety director jobs pay per year?

As of Sep 5, 2026, the average yearly pay for medical safety director in the United States is $162,390.00, according to ZipRecruiter salary data. Most workers in this role earn between $100,000.00 and $207,000.00 per year, depending on experience, location, and employer.

What does a medical safety director do?

A Medical Safety Director is responsible for overseeing the safety of pharmaceutical products or medical devices throughout their lifecycle. They lead teams that monitor, assess, and manage risks related to patient safety, ensuring compliance with regulatory requirements. Their duties often include reviewing safety data, reporting adverse events, and implementing risk management strategies. Medical Safety Directors work closely with regulatory agencies, clinical teams, and other departments to protect patient well-being and improve product safety.

What are the key skills and qualifications needed to thrive as a medical safety director, and why are they important?

To thrive as a Medical Safety Director, you need extensive knowledge of pharmacovigilance, regulatory requirements, and clinical risk assessment, typically supported by a degree in medicine, pharmacy, or life sciences. Familiarity with safety databases (like Argus or ArisGlobal), signal detection tools, and relevant certifications (such as RAC or CCRA) is highly valued. Excellent leadership, analytical thinking, and effective communication are crucial soft skills for guiding teams and interacting with regulatory authorities. These competencies ensure patient safety, regulatory compliance, and successful management of medical product risks in the healthcare industry.

What are some common challenges faced by a medical safety director, and how can they be managed effectively?

Medical Safety Directors often navigate challenges such as rapidly evolving regulatory requirements, managing cross-functional safety teams, and responding to urgent safety signals. Effective management involves staying updated on global pharmacovigilance regulations, fostering strong communication across clinical, regulatory, and research teams, and implementing robust risk assessment processes. Proactive collaboration and continuous training are key to ensuring timely and accurate safety data reporting, which helps mitigate risks and maintain compliance.

What is the difference between Medical Safety Director vs Medical Safety Specialist?

AspectMedical Safety DirectorMedical Safety Specialist
CredentialsMedical degree, safety certifications, experience in drug safetyRelated certifications, such as pharmacovigilance training, with less managerial experience
Work EnvironmentOversees safety programs, manages teams, collaborates with regulatory agenciesSupports safety data collection, conducts analysis, assists in safety reporting
Employer & Industry UsagePharmaceutical companies, biotech firms, healthcare organizationsPharmaceutical companies, contract research organizations, healthcare settings

The Medical Safety Director typically holds a leadership role, overseeing safety strategies and teams, while the Medical Safety Specialist focuses on data analysis and safety reporting. Both roles require relevant safety certifications and industry experience, but the director has broader responsibilities and managerial duties.

Do medical safety directors get paid more?

Medical Safety Directors typically earn higher salaries compared to other safety or compliance roles due to their specialized expertise, leadership responsibilities, and often advanced certifications such as RAC or CSP. Their compensation varies based on experience, industry, and organization size, but they generally receive higher pay reflecting their critical role in ensuring patient and staff safety in healthcare settings.

How much does a Medical Safety Director make in the US?

A Medical Safety Director in the US typically earns between $150,000 and $200,000 annually, depending on experience, location, and the size of the organization. They often hold advanced certifications and have extensive knowledge of pharmacovigilance, risk management, and regulatory compliance.
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Medical Safety Director jobs near you
Infographic showing various Medical Safety Director job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 15% Part Time, and 6% Contract. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $162,390 per year, or $78.1 per hour.

Associate Medical Director, Medical Safety

Scorpion Therapeutics

California, MD • On-site

$150 - $230/hr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 6 days ago

Job description

Responsibilities:
  • Implement global safety strategy and monitor overall safety profile for investigational and marketed products throughout lifecycle.
  • Generate pre- and post-marketing safety deliverables (signal detection, benefit-risk evaluation, risk management).
  • Interface cross-functionally and with external Regulatory Authorities.
  • Manage safety assessment activities: review aggregate safety analyses/scientific literature, prepare safety reports, and communicate changes in product risk profile.
  • Provide Medical Safety/PV inputs to clinical development, investigator-sponsored programs, compassionate use, and disease monitoring programs; liaise with study and safety stakeholders (Clinical Sciences/Operations, Medical Affairs, Biometrics, Regulatory Affairs, CROs, DMCs).
  • Support global launch activities with PV/medical safety inputs.
  • Prepare/review safety sections for clinical, regulatory, and scientific documents (protocols, consent forms, CRFs, statistical plans, clinical study reports/synopses, integrated safety summaries, NDA/BLA, MAA, CTD submissions, regulatory responses, IRB/EC requests, briefing books, manuscripts).
  • Maintain Company Core Safety Information (CCSI) implementation across RSI/labeling; review relevant literature for signals.
  • Conduct signal detection, evaluation, validation, and communicate safety assessments.
  • Chair Safety Management Team (SMT); oversee preparation/review of aggregate safety reports (PSUR/PBRER, PADER, DSUR, IND Annual Reports, 6-month SUSAR line listings).
  • Contribute to Risk Management Plans (RMPs); guide MedDRA/WHODrug coding.
  • Ensure compliance with PV regulations/guidelines and support audits/inspections.
  • Represent PV in cross-functional forums; contribute to PV KPIs; stay current on PV guidance.
Required:
  • MD (or equivalent); medical licensure in at least one state preferred.
  • Minimum 3 years Drug Safety/Pharmacovigilance or 3+ years clinical development.
Required Skills/Abilities:
  • Working knowledge of global PV regulatory environment and Good Pharmacovigilance Practices (GVP).
  • Working knowledge of safety databases (e.g., ARISg/ARGUS) and electronic data capture.
  • MedDRA training and coding dictionary knowledge.
  • Ability to manage multiple deadlines; strong written/oral communication and cross-functional teamwork.
  • Computer literacy (Regulatory databases, Excel, PowerPoint, Word); some travel possible.
Benefits (US candidates):
  • medical/dental/vision insurance, 401(k), flexible paid vacation; discretionary bonus/incentive and potential equity grants.
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