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Manufacturing Manager Jobs in San Ramon, CA (NOW HIRING)

GeneFab

Sr. Manager/Manager, Manufacturing

Alameda, CA

$140K - $180K/yr

The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...

Grifols

Manufacturing Digital Manager

Clayton, CA

Clayton NC Position Summary The Grifols Therapeutics Manager of Manufacturing Digital Systems, is the GT site functional leader responsible for site-level functional ownership, governance, integrity ...

Kinder's

Manager, Co-Manufacturing

Walnut Creek, CA · On-site

$135K - $155K/yr

As Contract Manufacturing Manager, you will be responsible for managing key relationships with our co-manufacturing partners to support the production of Kinder's premium products. You'll serve as ...

Kinder's

Manager, Co-Manufacturing

Walnut Creek, CA · Hybrid

$135K - $155K/yr

As Contract Manufacturing Manager, you will be responsible for managing key relationships with our co-manufacturing partners to support the production of Kinder's premium products. You'll serve as ...

Kinder's

Manager, Co-Manufacturing

Walnut Creek, CA · Hybrid

$135K - $155K/yr

As Contract Manufacturing Manager, you will be responsible for managing key relationships with our co-manufacturing partners to support the production of Kinder's premium products. You'll serve as ...

Cellares

Supervisor, Manufacturing

South San Francisco, CA · On-site

$90K - $210K/yr

Oversee the hiring, development, and performance management of staff within team * Follow compliance and regulatory requirements and current Good Manufacturing Practices (cGMPs) and understand 'why ...

Mizuho OSI

Supervisor, Manufacturing

Union City, CA

$67K - $92K/yr

The Manufacturing Supervisor manages their team (manufacturing lines, cells, or areas) as an operational team with responsibility for accomplishing company goals and targets in accordance with ...

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Manufacturing Manager information

See San Ramon, CA salary details

$44.1K

$110.9K

$166K

How much do manufacturing manager jobs pay per year?

As of Jul 18, 2026, the average yearly pay for manufacturing manager in San Ramon, CA is $110,856.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,600.00 and $132,400.00 per year, depending on experience, location, and employer.

What are common challenges a Manufacturing Manager faces when implementing process improvements?

Manufacturing Managers often encounter resistance to change from team members who are accustomed to established processes. Additionally, balancing production targets with the need to test and refine new procedures can be challenging. Clear communication, thorough training, and involving staff in problem-solving can help overcome these obstacles and lead to successful implementation of improvements. Managers also need to ensure minimal disruption to quality and output during transitions.

What is the highest salary for a production manager?

The highest salary for a manufacturing manager, including production managers, can exceed $130,000 annually, especially in large corporations or high-cost regions. Senior managers with extensive experience, advanced certifications, and oversight of multiple facilities may earn higher compensation, often supplemented with bonuses and benefits.

What is the role of a manufacturing manager?

A manufacturing manager oversees the production process in a factory or plant, ensuring that manufacturing operations run efficiently, safely, and meet quality standards. They coordinate staff, manage resources, implement production schedules, and optimize workflows, often using tools like ERP systems. Strong leadership, problem-solving skills, and knowledge of safety regulations are essential for this role.

What are the key skills and qualifications needed to thrive as a Manufacturing Manager, and why are they important?

To thrive as a Manufacturing Manager, you need strong leadership abilities, a background in engineering or manufacturing, and experience with production planning and quality control, often supported by a relevant bachelor's degree. Familiarity with ERP systems, Lean Manufacturing principles, and Six Sigma certification are highly valued in this role. Outstanding problem-solving, communication, and team-building skills help drive productivity and foster a positive work environment. These competencies ensure efficient production processes, high-quality output, and the achievement of business objectives in a competitive manufacturing landscape.

What does a Manufacturing Manager do?

A Manufacturing Manager oversees the production process in a manufacturing facility to ensure that products are made efficiently, on time, and meet quality standards. They are responsible for planning and organizing production schedules, managing staff, coordinating maintenance, and implementing safety protocols. Manufacturing Managers also work to optimize processes, reduce costs, and resolve any issues that may arise during production.

How to become a manufacturing manager?

To become a manufacturing manager, candidates typically need a bachelor's degree in engineering, manufacturing, or a related field, along with several years of experience in manufacturing or production roles. Developing skills in leadership, process improvement, and familiarity with manufacturing software or tools like ERP systems is also important. Some positions may require professional certifications such as Six Sigma or Lean Manufacturing.

What is the highest paying job in manufacturing?

The highest paying roles in manufacturing are often executive positions such as Vice President of Manufacturing or Plant Director, which can earn six-figure salaries. These roles typically require extensive experience, leadership skills, and knowledge of production processes and supply chain management.

What Does a Manufacturing Manager Do?

The job duties of a manufacturing manager include working to oversee the production process for a company in a manufacturing facility. Your responsibilities may involve managing the use of equipment and employee operations. You may be in charge of a single department or oversee the entire operation in a production plant. You are typically responsible for setting up the equipment, managing the workflow for a production project, and ensuring efficiency during the process. You are also responsible for supervising staff and delegating to production floor managers when necessary.

More about Manufacturing Manager jobs
What are the most commonly searched types of Manufacturing jobs in San Ramon, CA? The most popular types of Manufacturing jobs in San Ramon, CA are:
What are popular job titles related to Manufacturing Manager jobs in San Ramon, CA? For Manufacturing Manager jobs in San Ramon, CA, the most frequently searched job titles are:
What job categories do people searching Manufacturing Manager jobs in San Ramon, CA look for? The top searched job categories for Manufacturing Manager jobs in San Ramon, CA are:
What cities near San Ramon, CA are hiring for Manufacturing Manager jobs? Cities near San Ramon, CA with the most Manufacturing Manager job openings:
Manufacturing Manager jobs near you
Infographic showing various Manufacturing Manager job openings in San Ramon, CA as of July 2026, with employment types broken down into 85% Full Time, 13% Part Time, 1% Temporary, and 1% Contract. Highlights an 86% Physical, 1% Hybrid, and 13% Remote job distribution, with an average salary of $110,856 per year, or $53.3 per hour.

Sr. Manager/Manager, Manufacturing

GeneFab

Alameda, CA • On-site

Full-time

Re-posted 17 days ago

Job description

GeneFab is seeking an experienced and highly motivated Sr. Manager/Manager, Manufacturing to lead and oversee cGMP manufacturing operations for our Cell and Gene Therapy CDMO. This position carries direct responsibility for managing day-to-day manufacturing activities, building and developing a high-performing operations team, and ensuring the delivery of safe, high-quality cell and gene therapy products in support of client clinical programs. The ideal candidate brings deep hands-on experience in cGMP biologics or advanced therapy manufacturing, a strong quality mindset, and a proven ability to lead teams in a fast-paced, multi-product environment.
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process Development to ensure manufacturing readiness, GMP compliance, and continuous improvement across all client programs. This individual will be expected to operate with strong ownership and accountability, driving both team performance and operational excellence while maintaining the highest standards of patient safety and product quality.
This is a hands-on operational role requiring significant on-the-floor presence and direct Gemba of manufacturing areas during processing runs.
Key Responsibilities:
The Sr. Manager/Manager, Manufacturing is expected to maintain a strong operational presence in the manufacturing suites and support areas, actively observing and engaging in daily GMP operations. Key responsibilities include:
  • Lead and manage daily cGMP manufacturing operations across cell and gene therapy programs, ensuring all activities are executed in compliance with approved batch records, SOPs, and applicable regulatory requirements.
  • Build, develop, and retain a high-performing manufacturing team; hire, onboard, mentor, and conduct performance reviews for manufacturing specialists, senior associates, and supervisors.
  • Champion a culture of quality, patient safety, and operational excellence across all manufacturing activities, ensuring team members always understand and uphold cGMP standards.
  • Partner with MSAT to plan and execute Engineering Runs and Technology Transfer Runs for new client programs introduced to the site, supporting smooth transitions from process development to GMP manufacturing.
  • Collaborate with Quality Assurance to ensure on-time closure of deviations, CAPAs, and change controls; serve as manufacturing owner for investigations and provide thorough, technically sound root cause analyses.
  • Review and approve GMP-controlled documents including standard operating procedures, master batch records, material specifications, training materials, and validation protocols and reports.
  • Develop and maintain a comprehensive training program for cGMP operations and manufacturing systems, ensuring all staff achieve and sustain the competency level required for multi-product clinical manufacturing.
  • Manage manufacturing scheduling, ensuring people, facility, equipment, materials, and documentation are aligned and available to support program timelines and site capacity requirements.
  • Oversee and provide direct on-the-floor operational support during all manufacturing runs and processing activities; maintain regular Gemba walks through manufacturing suites and support areas to observe operations firsthand, identify improvement opportunities, and ensure compliance with procedures and cGMP practices.
  • Drive continuous improvement initiatives aimed at increasing right-first-time performance, reducing operational cycle times, and improving overall manufacturing efficiency.
  • Develop, track, and report departmental KPIs; present operational performance updates and contribute to the development of annual department goals and budgets.
  • Support capacity planning for clinical and commercial manufacturing campaigns; proactively identify and escalate resourcing or scheduling risks that could impact client program delivery.
  • Build and maintain effective cross-functional partnerships with Quality, Supply Chain, MSAT, EHS, Facilities and Engineering, and client teams to ensure alignment and seamless execution across all operational activities.
  • Support regulatory inspection readiness activities including internal audits, mock inspections, and preparation of manufacturing areas and documentation for FDA, EMA, or other agency inspections.

Supervisory Responsibilities:
  • Hire, mentor, and develop exceptional manufacturing talent at all levels, from entry-level associates to senior supervisors.
  • Conduct regular performance reviews and identify opportunities for career growth, skills development, and advancement.
  • Foster a culture of collaboration, cross-functional inclusion, execution excellence, and effective communication to build a high-performing manufacturing team.
  • Provide clear direction, coaching, and accountability to direct reports; resolve team conflicts and performance issues in a timely and constructive manner.

Qualifications:
  • Bachelor's degree in a relevant science or engineering discipline required; advanced degree (M.S. or Ph.D.) preferred.
  • Minimum of 6 years of relevant work experience within a pharmaceutical, biotechnology, or similarly regulated industry, including at least 5 years of direct hands-on experience in cGMP biologics or cell and gene therapy manufacturing.
  • Minimum of 3 years of experience in a supervisory or management role with direct people leadership responsibility.
  • Experience in cell and gene therapy manufacturing (autologous or allogeneic cell therapy, lentiviral or AAV viral vector production) is strongly preferred; CDMO experience is a significant plus.
  • Strong technical writing capability with demonstrated experience authoring, reviewing, approving, and training staff on SOPs, batch records, change controls, deviations, and CAPAs.
  • Thorough knowledge of cGMP regulations and regulatory guidelines including 21 CFR Parts 210/211/600/610 and EU GMP, with a demonstrated track record of maintaining compliance in a regulated manufacturing environment.
  • Proven leadership ability to make sound decisions under pressure, manage competing priorities, and drive accountability across a manufacturing team in a dynamic, multi-program environment.
  • Strong interpersonal and communication skills with the ability to build effective relationships across functions and engage and influence team members in a matrixed organization.
  • Proficient in MS Office applications; familiarity with electronic batch record (EBR), manufacturing execution system (MES), and quality management system (QMS) platforms preferred.

Compensation:
  • Compensation range for Manager: 140-160K
  • Compensation range for Sr. Manager: 160-180K

$140,000 - $180,000 a year
About GeneFab
GeneFab is a contract manufacturing and synthetic biology biofoundry focused on cell and gene therapies. GeneFab was formed in 2023 with a vision to combine industry leading expertise in synthetic biology with advanced cGMP capabilities in order to accelerate the development and commercialization of genetic medicines. GeneFab offers its customers an extensive technology platform and know-how that spans early stage product design, technical development, and cGMP compliant production. GeneFab's technology platform includes bioinformatic-guided discovery of cell type promoters, directed evolution of small molecule-regulated gene switches, and the engineering of highly sensitive kill switches for enhanced safety and control of cellular therapies.
We are committed to an inclusive and diverse GeneFab. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse GeneFab team. We welcome people of different backgrounds, experiences, abilities, and perspectives and are an equal opportunity employer.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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